Inhibition of Bcl-6 Expression Ameliorates Asthmatic Characteristics in Mice

Repressing #Bcl6 in an asthmatic mouse model disrupts #Tfhcell differentiation and B-cell responses, reduces #IgE levels in #serum and BALF & alleviates #AirwayInflammation, and highlights Bcl-6–Tfh signaling as a potential therapeutic target in #asthma.

Read: doi.org/10.1007/s115...

This study identifies #BCL6 suppression as a promising strategy to reduce #Tfhcell differentiation, attenuate #IgE secretion, and mitigate #AirwayInflammation, thereby highlighting its therapeutic potential in #Asthma. #medsky

Read more: link.springer.com/article/10.1...