Congratulations to our #UTeachDallas program ~ stem education minor graduates! They are ready for their next adventure ~ several are starting to teach for the rest of the year and several are going on to medical/graduate school. spotlighting them over the next few days.
#utdgrad #utdscience

Congratulations to UTD SME - UTeach Dallas Dept Annual Award Winners! Wesley Tyree, Graduate Student Award; Marissa Distin, Undergraduate Student Award; and Haley Bilbray, BS '14 MS '20, Alumni Award! We are so very proud of them all.
#awardwinners #stemeducation #utdscience

"First day of Fall" with Earth Diagram

Earth Orbit dagrams and explanations with definitions or equinox and solstice for December, March, June and September

Happy First Day of Fall Comets! Today is the Autumnal Equinox, when the day and night are of equal length. Equinox occurs twice a year in Earth's orbit, once in the spring and once in the fall. 🌞🌎💫

#STEMeducation #UTDSME #uteachdallas #utdscience #autumnalequinox

First day of fall with Earth diagram

Earth orbit diagrams with definitions of Equinox and Solstice for December, March, June and September

Happy First Day of Fall Comets! Today is the Autumnal Equinox, when the day and night are of equal length. Equinox occurs twice a year in Earth's orbit, once in the spring and once in the fall. 🌞🌎💫

#STEMeducation #UTDSME #uteachdallas #utdscience #autumnalequinox

WOW! Naturally Inquisitive, Science Unplugged: Live Experiments and Fun!
Wednesday 3-4:30!
Stop by the SME/UTeach Dallas booth for UV beads & math fun. FO atrium #utd #utdscience #utdsme #utdwelcome

Congrats to our MAT grads! We celebrated that Andy, Cristina & Walli have completed their Masters in Arts of Teaching in Science or Math Education this summer. We will miss our fab TAs! Cristina & Andy are completing their #UTeachDallas teaching certif in Dec.
#utdsme #utdscience

On 07/24 #UTDSME-#UTeachDallas hosted STEM-tastic Day, PD for teachers to learn about topics such as Zebrafish, Astro, Physics, CS, & the integration of art by visiting the new Crow Museum on campus!
Great to have our #UTDalumni back as presenters & attendees.
#utdscience #stemeducation

On 07/24 #UTDSME-#UTeachDallas hosted STEM-tastic Day, PD for teachers to learn about topics such as Zebrafish, Astro, Physics, CS, & the integration of art by visiting the new Crow Museum on campus!
Great to have our #UTDalumni back as presenters & attendees.
#utdscience #stemeducation

teachers in a CS workshop

more teachers in a CS workshop

#UTeachDallas hosted the final #WeTeach_CS PD Workshop of summer for our cohort led by Mr Lalani & Ms Gregory & we teamed up w #SMU's cohort. Designed to prepare Ts for the Tx #computerscience certif exam by creatively teaching them CS #utdsme #utd #utdscience #stemeducation

teachers in a PD workshop

more teachers in a PD workshop

#UTeachDallas hosted the final #WeTeach_CS PD Workshop of summer for our cohort led by Mr Lalani & Ms Gregory & we teamed up w #SMU's cohort. Designed to prepare Ts for the Tx #computerscience certif exam by creatively teaching them CS #utdsme #utd #utdscience #stemeducation

Collage of pictures of students at UTeach Dallas orientation table

collage of pictures of students at UTeach Dallas orientation table

Summer Orientations are going strong!! #UTeachDallas will have the largest incoming Step 1 classes ever this fall with 7 sections of S1. We are beyond excited for this next semester and the program. Welcome class of '29 !

#utdallas #utdorientation #utdscience #uteachnation

Happy Independence Day! 🇺🇸

Learn about the chemistry and math involved in fireworks!

#uteachdallas #fourthofjuly🇺🇸 #utdallas #utdsme #utdscience

Happy Independence Day! 🇺🇸

Learn about the chemistry and math involved in fireworks!

#uteachdallas #fourthofjuly🇺🇸 #utdallas #utdsme #utdscience

SME - UTeach Dallas Professors Gregory, Hennessy, and Lalani are in Indiana sharing their Computer Science skills with a week of Intro to Programming for K-5 and 6-12.
#CSPD #utdscience #utdsme #uteachdallas #csta #cstaindiana

SME - UTeach Dallas Professors Gregory, Hennessy, and Lalani are in Indiana sharing their Computer Science skills with a week of Intro to Programming for K-5 and 6-12.
#CSPD #utdscience #utdsme #uteachdallas #csta #cstaindiana

Join us for a fun day of hands-on learning at UTD
*Thurs July 24 9am-3pm
* K-12 Math/Science/CS teachers!
* $30 fee covers all sessions, lunch, & parking.
* CPE certificate
REGISTRATION at QR code
#ProfessionalDevelopment #stemeducation #utdscience #utdsme #uteachdallas

Congrats to our #UTeachDallas Class of '25! These students earned their STEM Education Minor & Teaching Certificate with their major. We start our Graduate Spotlights with these #utdbiology Kathryn Ditzler, Khanh Hoang, & Jonathan Islas.
#utdgrad #utdscience #stemed #dallasisd

We celebrated our #UTeachDallas S25 Apprentice Teacher grads (-2 clinical teaching in Houston). Very proud of them for completing their #STEMEducation minor & teaching certif w/ their STEM degree!🎉👏
#preserviceteacher #UTeachnation #UTeachalumni #utdscience

Our @CharlesButtFdn Scholars have earned the #Scholarship for Aspiring Teachers. Aman Rahman is our next #ScholarSpotlight. He is a #utdChemistry major & #UTeachDallas #STEMEducation Minor in Chemistry 7-12 along with his degree.
#CBFFriday #preserviceteacher #utdscience 1/2

female student holding a scholarship certificate

Our Charles Butt Scholars have earned the Scholarship for Aspiring Teachers. Jahnavi Yadlapati. Jahnavi is a Data Science major who is pursuing her #UTeachDallas #STEMEducation Minor in Math 7-12 along with her degree.
1/2
#CBFFriday #scholarship #preserviceteacher #cbuttfoundation #utdscience

Tonight our PBI students joined our Apprentice Teacher class to quiz them on all they really need to know on the ins & outs of AT semester. Lots of good questions & discussion.

#preserviceteacher #stemeducation #utdscience #uteachnation

Founded in 1988, 3/14 became known as Pi Day to celebrate the mathematical constant π (pi) because the numbers 3, 1 and 4 are the first significant digits of π which corresponds to the date 3/14.
How will you celebrate Pi Day?

#piday #utdscience #uteachdallas #utdsme #STEMeducation

Founded in 1988, 3/14 became known as Pi Day to celebrate the mathematical constant π (pi) because the numbers 3, 1 and 4 are the first significant digits of π which corresponds to the date 3/14.
How will you celebrate Pi Day?

#piday #utdscience #uteachdallas #utdsme #STEMeducation

Congratulations to Mohammad Saleh! Awarded Pearce HS, Richardson ISD, Red Apple ~ Outstanding First Year Teacher of the Year!
We are so proud of you! #uteachdallasalumni #utdsmematalumni #utdscience #instarisd

Congratulations to Mohammad Saleh! Awarded Pearce HS, Richardson ISD, Red Apple ~ Outstanding First Year Teacher of the Year!
We are so proud of you! #uteachdallasalumni #utdsmematalumni #utdscience #instarisd

Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition Poly(ADP-ribose) polymerase1 (PARP1) plays a vital role in DNA repair, and its inhibition in cancer cells may cause cell apoptosis. In this study, we investigated the effects of a PARP1 variant, V762A, which is strongly associated with several cancers in humans, on the inhibition of PARP1 by three FDA-approved inhibitors: niraparib, rucaparib, and talazoparib. Specifically, we compared the inhibition of the mutant to that of wild-type (WT) PARP1. Additionally, we investigated how the mutation influences the binding of these inhibitors to PARP1. Our work suggests that while mutant PARP1 exhibits only minor differences in residual fluctuations, backbone deviations, and residue motion correlations compared to the WT under niraparib and rucaparib inhibitions, it shows significant and distinct differences in these features when inhibited by talazoparib. Among the three inhibitions, talazoparib inhibition uniquely lowers the average residue fluctuations in the mutant than the WT including lower fluctuations of mutant’s N- and C-terminal residues in the catalytic domain, conserved H-Y-E traid residues, and donor loop (D-loop) residues which are important for catalysis more effectively than other inhibitions. However, talazoparib also significantly enhances destabilizing interactions between the mutation site in the HD domain in the mutant than WT. Further, among the three inhibitions, talazoparib inhibition uniquely and significantly disrupts the functional fluctuations of terminal regions in the mutant, which are otherwise present in the WT. The mutation and inhibition do not significantly affect PARP1’s essential dynamics. Lastly, these inhibitors bind to the V762A mutant more effectively than to the WT, with similar binding free energies between them.

Interested in how cancer mutations affect drug inhibition?
Check out our latest paper, Published as part of The Journal of Physical Chemistry B special issue “At the Cutting Edge of Theoretical and Computational Biophysics”.
#NIHFunded #UTDScience
pubs.acs.org/doi/full/10....

Our last UTeach Dallas AT grad for F24 is neuroscience major, Rezwan Ross Siraj. He has been hired at Allen High School to teach Advanced Chemistry. ⚛️ Teachers touch the future.
#allenisd
#stemeducation #preserviceteacher #uteachnation #utdallasalumni #utdgrad #utdscience

Our next UTeach Dallas spotlight is Malaek Shalabi, Neuroscience major. She will be looking for a science teaching job in the area. We know you will do great teaching the next generation.
>>
#uteachnation #stemeducation #preserviceteacher #utdgrad #utdscience #utdalumni #uteachalumni