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DANTE Pulse Changed Our Clinical Routine and Research by Yasutaka Fushimi, MD, PhD; et al. (Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan)

Vessel wall MRI (VW-MRI) has become an essential tool for characterizing pathological features of the vessel wall in clinical practice. Its clinical importance is well established in evaluating atherosclerotic disease, both extracranially and intracranially. 

With the introduction of additive pre-pulses such as motion-sensitized driven equilibrium (MSDE) and delay alternating with nutation for tailored excitation (DANTE), VW-MRI has expanded its potential applications beyond atherosclerosis and has improved the assessment of atherosclerotic lesions.
 
While MSDE is widely used, its low diffusion-sensitizing capability can cause blurring and T2-weighted effects. 
In contrast, the DANTE pulse attenuates signals from flowing spins by applying a train of low flip-angle pulses along the flow direction, resulting in less attenuation of signals from static tissue. 

The authors have encountered various clinical cases in which non-contrast and contrast-enhanced DANTE T1-SPACE imaging helped visualize abnormal findings. This review presents representative cases acquired on a 3T scanner, illustrating the clinical utility of DANTE T1-SPACE imaging.

Shout-out to the co-authors: Sachi Okuchi, Akihiko Sakata, Satoshi Nakajima, Takayuki Yamamoto, John Grinstead, Sinyeob Ahn, Yuji Nakamoto

DANTE Pulse Changed Our Clinical Routine and Research by Yasutaka Fushimi, MD, PhD; et al. (Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan) Vessel wall MRI (VW-MRI) has become an essential tool for characterizing pathological features of the vessel wall in clinical practice. Its clinical importance is well established in evaluating atherosclerotic disease, both extracranially and intracranially. With the introduction of additive pre-pulses such as motion-sensitized driven equilibrium (MSDE) and delay alternating with nutation for tailored excitation (DANTE), VW-MRI has expanded its potential applications beyond atherosclerosis and has improved the assessment of atherosclerotic lesions. While MSDE is widely used, its low diffusion-sensitizing capability can cause blurring and T2-weighted effects. In contrast, the DANTE pulse attenuates signals from flowing spins by applying a train of low flip-angle pulses along the flow direction, resulting in less attenuation of signals from static tissue. The authors have encountered various clinical cases in which non-contrast and contrast-enhanced DANTE T1-SPACE imaging helped visualize abnormal findings. This review presents representative cases acquired on a 3T scanner, illustrating the clinical utility of DANTE T1-SPACE imaging. Shout-out to the co-authors: Sachi Okuchi, Akihiko Sakata, Satoshi Nakajima, Takayuki Yamamoto, John Grinstead, Sinyeob Ahn, Yuji Nakamoto

DANTE Pulse Changed Our Clinical Routine and Research by Yasutaka Fushimi, MD, PhD; et al. (Kyoto University, Japan).

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Optimizing scan efficiency of T1-weighted imaging for whole-brain intracranial vessel wall imaging
Cao, Q., Fan, Z. et al.
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