Figure 7. NRT1.1B integrates compound environmental signals in plants.
(M) A proposed model of nitrate-ABA coordinated responses mediated by NRT1.1B.
Under low-nitrate conditions without ABA, NLP4 interacts with SPX4 and is sequestered in the cytoplasm. ABA perception enhances the NRT1.1B-SPX4 interaction, thereby promoting NLP4 release and translocation into the nucleus, and ultimately activates downstream ABA responses.
Under high-nitrate conditions, nitrate competes with ABA for NRT1.1B binding, and NRT1.1B shifts to sense the nitrate signal.
Great work by Ma et al. (2025) on how NRT1.1B, a traditionally recognized #nitrate receptor, can directly perceive extracellular #AbscisicAcid (ABA) in a nitrate-antagonistic manner, thus enabling 🌾plants to integrate nutrient and abiotic stress cues (N level & drought)
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