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📰 [PressRelease] – MaaT Pharma Presents the ARES Phase 3 Pivotal Trial Final Data During the Presidential Plenary Session at the 52nd Annual Meeting of the EBMT.

👉 Read the press release: www.maatpharma.com/march-23-202...

@theebmt.bsky.social
#Cancer #Hematology #AlloHCT #Microbiome #EBMT26

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🧬 Even fully HLA-matched transplants can diverge in outcomes.

A study found SNPs in HLA-DOA/DOB linked to survival and GvHD after cord blood transplantation — genes that regulate peptide editing by HLA-DM.

Matching classical alleles isn’t enough; the editors matter too.

#AlloHCT #Genomics

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ASAP Trial Challenges Standard Practice of Remission Induction Before Transplant in AML | ASH Clinical News | American Society of Hematology

Despite the widespread clinical practice of inducing CR before #alloHCT in patients with R/R #AML, findings from the ASAP trial challenge this standard, with evidence showing that genetics, not remission status, determine overall survival after #transplant: ow.ly/eiu450Xgxxi
#HemeSky #leukemia

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Emerging novel therapies for steroid-refractory acute graft-versus-host disease: recent advances and future directions Acute graft-versus-host disease (aGVHD) is a significant complication of allogeneic hematopoietic cell transplantation (allo-HCT), characterized by im…

Proud to share that MaaT013 (Xervyteg®) clinical data were featured in the latest special issue on acute Graft-versus-Host Disease (#aGvHD) in Current Opinion in Immunology.

🔗Open-access article here: sciencedirect.com/science/arti...
#AlloHCT #Hematology

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"God created all diseases except GvHD, that we created" Hillard Lazarus
Transplanters carry guilt of poor patient outcomes and NRM.
The type of cGVHD 👇 reminds me why I vowed NEVER to use tac/mtx again. With ptCY & other data IMO it is no longer acceptable.
#GvHD #alloHCT

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Explore the latest ASTCT evidence-based guidelines for #alloHCT in severe aplastic anemia (SAA). Key updates include graft source preferences, expanded donor options and refined #GVHD prophylaxis. Read more: t.co/iNKZB8J2ir #MedSky

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Our @BMTCTN 1506 deep drive on FLT3 MRD and #alloHCT #AML @BloodJournal
-15% have micro-clones = worse RFS
-MRD+ relapse with WT or with clones persisting (can monitoring in tailor duration?)
-if u eradicate MRD, u r fine
-Some micro-clones survive and strike if gilt stops

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Improved Patient-Reported Outcomes With Post-Transplant Cyclophosphamide: A Quality-of-Life Evaluation and 2-Year Outcomes of BMT CTN 1703 The BMT CTN 1703 phase III trial confirmed that graft-versus-host disease (GVHD) prophylaxis with post-transplantation cyclophosphamide (PTCy), tacrolimus (Tac), and mycophenolate mofetil (MMF) result...

Our new @BMTCTN 1703 analysis busts a few myths:
- QOL improved with ptCY
- 🩸Cystitis not worse
- 2yr GRFS superior 42% vs 29%, p=0.001
- ptCY relapse NOT higher
@sghmd.bsky.social TY to Mike Martens for elegant analysis #GvHD #alloHCT #BMT
ascopubs.org/doi/10.1200/...

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