After a gentle touch to a mouse’s injured paw, a brain region involved in the emotional side of pain lights up, as seen in this mouse brain cross-section. The blue and pink signals mark genes that switch on when neurons become active. This allowed the researchers to map a pain-responsive hotspot and then target a specific opioid-related circuit. Image credit: Gregory Corder, Corinna Oswell, and Nora McCall
By splitting #pain into its component parts, researchers provide pain relief in #mice. In PNAS Journal Club: https://ow.ly/eHT750Y1eGh
#ChronicPain #opioid #MachineLearning #AnteriorCingulateCortex