World malaria report 2025: Growing biological threats, shrinking resources

This review highlights the 2025 #WorldMalariaReport, warning that #artemisinin resistance, diagnostic evasion, #insecticide‑resistant mosquitoes, & urban spread of #AnophelesStephensi threaten progress, while molecular surveillance offers hope. @unistra

Read: doi.org/10.1016/j.dc...

How Was Artemisinin Discovered and How Does It Work? Artemisinin was discovered in 1972 by Chinese scientist Tu Youyou, who isolated it from the sweet wormwood plant, Artemisia annua, after following a low temperature extraction hinted at in a fourth century medical text. It works because an endoperoxide bridge in the molecule is activated by iron inside malaria parasites, generating reactive radicals that rapidly kill the parasite. Today, artemisinin is the cornerstone of WHO-recommended artemisinin-based combination therapies for uncomplicated malaria.

From ancient herb to lifesaving medicine: how Tu Youyou isolated artemisinin and how this malaria fighter works in ACTs. #ACTs #ArtemisiaAnnua #Artemisinin #Malaria #TuYouyou

Check out our latest issue in @theinnovation.bsky.social !!
Volume 6, Issue 9 is now online!
www.cell.com/the-innovati...
#Sustainability #physics #artificialintelligence #energystorage #medicine #cancerresearch #raredisease #carbonneutral #environmentalhealth #artemisinin

Screenshot of the title/abstract of the new article ("Imported Malaria Outbreak in Military Personnel Returning from Peacekeeping Operation in South Sudan — Thailand, 2023") linked in this post.

Interesting piece on #peacekeepers coming home with #malaria.
www.ajtmh.org/view/journal...
...though we inverted this narrative a decade ago (in the wake of the Haitian #cholera epidemic) to highlight the risks of #UN peacekeepers introducing #artemisinin resistance into Africa (in next post⬇️).

In Bilal, my undercover journey to Europe, Fabrizio Gatti mentions in passing #artemisinin, discovered by #TuYouyou, as a prophylactic drug against #malaria. But when my youngest sister was in Ghana for work, she took old-fashioned #mefloquine.
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Opinion in this collection: #Plasmodium #falciparum #ringstage #plasticity & #drug #resistance, authored by Lucien Platon & Didier Menard. @pasteur.fr @upcite.bsky.social @unistra.fr @sorbonne-universite.fr #Antimalarial #Artemisinin

www.cell.com/trends/paras...

Opinion in this collection: Peeling the onion: how complex is the #artemisinin #resistance genetic trait of #malaria parasites? authored by M. Kucharski, S. Nayak, M. Gendrot, A.M. Dondorp & Z. Bozdech. #Plasmodium @ndm.ox.ac.uk @ox.ac.uk @tropicalmedicine.ox.ac.uk

www.cell.com/trends/paras...

#MPB

Exploring metabolic networks and engineering strategies to boost artemisinin production in *Artemisia annua* for improved malaria treatment.

#Artemisinin #Biotech

Details: maxapress.com/article/doi/...

New research article in The Lancet Microbe

The spread of molecular markers of #artemisinin partial resistance and diagnostic evasion in Eritrea: a retrospective molecular epidemiology study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #malaria #AMR #OpenAccess #OA

Inaccurate communication in health sciences: the case of ‘partial arte... sciencedirect.com/science/articl… #malaria #artemisinin .. when crying ‘wolf’ sounds hollow

Fears for spread of malaria in Africa as study finds resistance to frontline drug Signs of resistance to artemisinin in tenth of children with severe malaria similar to situation in Asia, say researchers

🦟"Fears for spread of #malaria in #Africa as study finds #resistance to frontline drug. Signs of resistance to #artemisinin in tenth of children with severe malaria similar to situation in Asia, say researchers" by @katlay.bsky.social via The #Guardian
www.theguardian.com/global-devel...

Fears for spread of malaria in Africa as study finds resistance to frontline drug Signs of resistance to artemisinin in tenth of children with severe malaria similar to situation in Asia, say researchers

Fears for spread of #malaria in #Africa as study finds resistance to frontline drug - www.theguardian.com/global-devel... "Signs of resistance to #artemisinin in tenth of children with severe malaria similar to situation in Asia, say researchers"

Very comprensive review: #Artemisinin Action and Resistance in Plasmodium falciparum: Trends in Parasitology