The impact of albumin conjugation on the cytotoxic properties of cisplatin, oxaliplatin and auranofin in cancer cells The role of human serum albumin (HSA) in the delivery of anticancer metallodrugs remains unclear and requires further investigation. To this end, bioconjugates of HSA with the metallodrugs cisplatin (...

#OpenAccess article by Tiziano Marzo 𝘦𝘵 𝘢𝘭.
#UniversityofFlorence

𝐓𝐡𝐞 𝐢𝐦𝐩𝐚𝐜𝐭 𝐨𝐟 𝐚𝐥𝐛𝐮𝐦𝐢𝐧 𝐜𝐨𝐧𝐣𝐮𝐠𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝐭𝐡𝐞 𝐜𝐲𝐭𝐨𝐭𝐨𝐱𝐢𝐜 𝐩𝐫𝐨𝐩𝐞𝐫𝐭𝐢𝐞𝐬 𝐨𝐟 𝐜𝐢𝐬𝐩𝐥𝐚𝐭𝐢𝐧, 𝐨𝐱𝐚𝐥𝐢𝐩𝐥𝐚𝐭𝐢𝐧 𝐚𝐧𝐝 𝐚𝐮𝐫𝐚𝐧𝐨𝐟𝐢𝐧 𝐢𝐧 𝐜𝐚𝐧𝐜𝐞𝐫 𝐜𝐞𝐥𝐥𝐬

#HSA #metallodrugs
#cisplatin #oxaliplatin #auranofin

🔗 doi.org/10.1039/D5QI01487E