Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer’s disease models Recent human genetic studies have highlighted the potential role of microglial genes and their regulatory functions in the pathogenesis of Alzheimer’s…

New Kim Lab paper! 🥳 BK lead a rigorous study of the effect of microglial knockdown of PU.1 (Spi1) in APPPS1 amyloid mice. Made multiple pathological measures worse, can be partially rescued by overexpression of target genes Syk & Fcgr1. #blueskyence #microglia www.sciencedirect.com/science/arti...

In a bid to demystify the biological labs familiar from his own research work, PDN postdoc Chu-Cheng Lin has built a LEGO model concept of an accurate biological laboratory set, and hopes to make it a reality.
www.pdn.cam.ac.uk/news/buildin...
#Science #BlueSkyence #BiologicalScience #LEGO

See you there science and sanity loving New Yorkers! #standupforscience #blueskyence

Vaccine shows promise against aggressive breast cancer | WashU Medicine Clinical trial targeted recurrence of hard-to-treat triple-negative breast cancer

As someone who had triple negative bc 15 years ago, this promising vaccine is great news! #blueskyence #washu #vaccines medicine.washu.edu/news/vaccine...