#UsualEpithelialHyperplasia doesn’t get more florid than this.
#Cytokeratin5 positive.
#ER variable.
Note that the apocrine cells next door are CK5 and ER negative.
#BreastPath
#pathology
#BlueskyPath
😉

#SolarLentigo
🔬Bulbous elongation of hyperpigmented rete ridges
🔬Increase in basal melanocytes
🔬In contrast to #LentigoMaligna no crowding of melanocytes and no 'clonal' atypia. Occasional mildly atypical cells OK
🔬Sun damaged collagen/elastin
😉💜
#Pathology
#Blueskypath

A beautiful example of #RadialScar. The clue to this diagnosis is to identify the characteristic elastotic stroma (distinct from a fibroblastic tubular carcinoma stroma) & then hunt for #myoepithelial cells at high 🔍
#pathology #blueskypath #bluepath
😉💚

The discohesive metastatic menace 😈
#LobularCarcinoma
📸 1 Endometrial invasion
📸 2 Bone marrow invasion (paratrabecular)
#pathology
#breastpath
#blueskypath
#pathsky

A textbook example of #Psoriasis
#pathology
#dermatology
#SkyPath #BlueskyPath
😉

Key #pathology skills. #Dissection and #Embedding.
#blueskypath
😂🎄🥳🎉

PAX-5

CD79a

DDX of superficial pediatric small round blue cell tumors are sarcomas (Ewing family and fusion-associated); rhabdomyosarcoma; lymphomas/leukemias; neuroblastoma #dermpath #surgpath #blueskypath #blueskydermpath #blueskysurgpath #hemepath #blueskyhemepath #pathology #blueskypathology

A 3-month-old baby with an enlarging, abscess-like bump on the anterior fontanelle. Additional lumps appeared on ear and scalp, with hair loss and eroded skin. What are your differentials?
#blueskypath #blueskyderm #pathsky #dermsky #dermpath #dermpathsky #pedipath #surgpath #pathology #dermatology

Acquired Reactive Perforating Dermatosis is a Variant of Prurigo Nodularis - PubMed Patients with chronic pruritus may develop scratch-induced lesions with elevated borders and central necrosis. This so-called umbilicated type of prurigo (UP) is rare and is assumed to develop prefere...

#blueskypath #pathsky #blueskydermpath #dermpathsky #dermatopathology #surgicalpathology #dermpath #derm #dermatology #pathology #inflammatoryderm

pubmed.ncbi.nlm.nih.gov/27349279/

Hypercellular basophilic tumor with closely packed glandular architecture.

The closely packed "glands" contain dense eosinophilic material and are lined by monotonous cells.

PAX-8 is positive.

Thyroglobulin is positive.

Metastatic thyroid carcinoma to the scalp. #dermpath #surgicalpath #blueskypath #blueskypathology #blueskydermpath #immunohistochemistry #pathology

Today’s case for #dermpath learning
#SquamoidEccrineDuctalCarcinoma
🔬Infiltrative architecture
🔬Squamous islands with pores intermixed with #syringoma like tubules
🔬4 #PerineuralInvasion
🎓Recurrence risk but no mets
🤓
#pathology
#dermatology
#Blueskypath

Granulomatous foreign body reaction after cosmatic filler
#pathology #dermpath #blueskypath #path