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Apixaban rarely raises INR to clinically significant levels. An analysis by DCRI fellow Seamus Hughes showed that, among 8,642 ARISTOTLE patients, the median INR was just 1.18. Elevated INR on a DOAC? Consider non-drug causes. #ACC26 #AFib #cvCoag #CardioSky

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#ACC26: 🆕 Insights from the CHAMPION-AF trial

Device-based LAA closure was comparable to NOAC therapy in reducing the combined rate of death from CV causes, stroke, or systemic embolism at 3️⃣ years in pts w/ #AFib who were candidates for #cvCoag.

More: https://bit.ly/4bIv5SA #CardioSky #MedSky

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🔥 #ACC26: HI-PEITHO

In patients with acute, intermediate-risk PE, ultrasound-facilitated, catheter-directed fibrinolysis plus #cvCoag led to a lower risk of PE-related death, cardiopulmonary decompensation or collapse, or recurrence of PE compared w/ anticoagulation alone. 🔗 https://bit.ly/4cbcwIf

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Podcast: Thrombosis in conversation Geoffrey Barnes and colleagues explore CAT and VTE

I was thrilled to be joined by Prof Marco Proietti to discuss important #VTE and #AFib trials presented at the ESC meeting. Lots of great science that impacts how we care for patients with #cvCoag meds. www.medthority.com/medical-educ... @medthority.bsky.social

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Help us understand what stewardship practices exist in health systems globally for #cvCoag and antithrombotic agents in the properties space! redcap.slhd.nsw.gov.au/surveys/?s=7... #ISTH2025 @isth.org @anticoagforum.bsky.social

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I often get asked if it’s safe to use #cvCoag mono therapy in patients with AF and stable CAD (i.e., PCI>6-12 months prior). @bbikdeli.bsky.social clearly shows safety and efficacy with OAC motherly in this population. #ACForum25

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Andrea Van Beek reminds us of ways the traditional “Coumadin Clinic” can evolve to have greater impact in helping our patients achieve evidence-based #cvCoag therapy. #ACForum25

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Congratulations to Drs Anne Rose, Tara Lech, David Para, and Allison Burnett for their leadership in Antithrombotic Stewardship. Each of them is a pioneer in patient safety in #cvCoag care. #ACForum25 @anticoagpharmd.bsky.social

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Dr. Isabelle Mahe on the extended anticoagulant treatment with a reduced versus full dose #apixaban in patients with cancer-associated #VTE

#ACC25 #JACCJournals #APICAT #CardioOnc #cvCoag #CardioSky

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Prior Oral Anticoagulant Use in OCEANIC-AF This secondary analysis of the Oral Factor 11a Inhibitor Asundexian as Novel Antithrombotic–Atrial Fibrillation (OCEANIC-AF) randomized clinical trial investigates if patients with atrial fibrillation...

This brand new analysis of the OCEANIC-AF study in @jama.com Cardiology explores the impact of prior #cvCoag treatment for #AF on using Factor XIa inhibitors. Does this challenge the belief that bleeding is front-loaded while stroke-risk is continuous in AF tx? jamanetwork.com/journals/jam...

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Analysis of quality measures before and after switching care models in MAQI2 anticoagulation clinics

What is the most effective way for large #cvCoag clinics to manage warfarin-treated patients? We found that moving to a "primary staff care" model where patients are assigned to individual staff/teams was the most effective. Read more here: www.sciencedirect.com/science/arti...

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Anticoagulation and Antiplatelet Therapy for Atrial Fibrillation and Stable Coronary Disease: Meta-analysis of Randomized Trials:

When does @bbikdeli.bsky.social sleep? I'm not sure - he's constantly publishing highly impactful work!! This week is no different. Check out this important meta-analysis on #cvCoag and #antiplatleet use in #AFib and stable #CAD! Less is more!!! @jaccjournals.bsky.social www.jacc.org/doi/10.1016/...

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Can a decision aid improve #AFib patient #cvCoag decision-making? Our 1117-patient randomized trial in the BMJ, showed improved decisional conflict, better shared decision-making, and greater patient knowledge. Check it out here: www.bmj.com/content/388/... www.bmj.com/content/bmj/...

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New Targets for Antithrombotic Medications: Seeking to Decouple Thrombosis from Hemostasis Arterial and venous thromboses are leading causes of morbidity and mortality worldwide. Numerous antithrombotic agents are currently available with an…

DOACs have been "the thing" in #cvCoag for over 10 years. What's coming next? Check out this brand new review article on emerging anti-thrombotic agents, focused on factor XI and GPVI agents, just published in @jthjournal.bsky.social! www.sciencedirect.com/science/arti...

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