#GIVLAARI (brand name for #givosaran ) approved by #FDA for adults with acute hepatic #porphyria: a clear unmet need. Label is broad and calls for d/c if anaphylaxis, renal or hepatic toxicity ...
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@Porphyria_Help @BPA_Porphyria @EASLedu @EASLnews $ALNY #givosaran meets reduction in composite annualized attack rate endpoint in ph3 ENVISION trial. 5/6 with baseline CKD worsened then returned to baseline. 1 had ALT>8xULN and d/c. 93/94 continue in open label phase #ILC2019
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