Engineered Fab glycosylation of a blood-brain barrier transporter single-chain variable fragment preserved functionality but did not impact anti-drug antibody formation
Godec, A. et al.
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#glycoengineering #bloodbrainbarrier #antibodyformation

Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases Hydroxylation of prolines to 4-trans-hydroxyproline (Hyp) is mediated by prolyl 4-hydroxylases (P4Hs). In plants, Hyps occur in Hydroxyproline-rich gl…

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Differential prolyl hydroxylation by six #Physcomitrella prolyl-4 hydroxylases
#glycoengineering #biopharmaceuticals #ispmf
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