Whole-brain clearing reveals region- and cell type-specific imbalances in inhibitory neurons in a mouse model for Kleefstra Syndrome GABAergic inhibition is essential for balanced brain function and is frequently disrupted in neurodevelopmental disorders such as autism spectrum disorder (ASD). The inhibition is generated by a diver...

Very interesting pre-print by @moritz-negwer.mstdn.science.ap.brid.gy and @naelnadifkasri-lab.bsky.social using a new clearing technology to capture the abundance of specific neuron populations in a mouse model of ASD. #autism #neurodevelopment #Kleefstra
www.biorxiv.org/content/10.1...

Día mundial del Síndrome de Kleefstra - Somosdisc@ Cada 17 de septiembre se conmemora el día mundial del síndrome de Kleefstra, con el fin de dar a conocer esta enfermedad genética.

🧬 Desde la RER-CSIC, hoy nos unimos al Día de Concienciación sobre el síndrome de #Kleefstra, una enfermedad rara de origen genético que afecta al desarrollo y la comunicación.
Más info: somosdisca.es/dia-mundial-...
#RareDiseases @csic.es

Kleefstra syndrome (KS) is a rare genetic disorder characterized by intellectual disability, often accompanied by a spectrum of complex physical and clinical features.

Learn more: www.idefine.org #kleefstra

You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness

Kleefstra syndrome (Ks) is a rare genetic disorder characterised by intellectual disability, often accompanied by a spectrum of complex physical and clinical features.
#kleefstra #9q34.3 #kleefstrasyndrome

Kleefstra Syndrome Awareness Day is on 17th September. Learn more at www.kleefstrasyndrome.org
#kleefstra #kleefstrasyndrome