New work out, with webtool to compare P. #knowlesi and P. #vivax temporal expression of the IDC (orthologs, or any gene of interest)🔥🔥
Reconfirming the suitability of Pk A1H1 as a model for Pv!
1st case of a natural P #knowlesi infection in a human was only reported 34 years later, when a U.S. Army surveyor acquired the infection while working in the forest in the state of Pahang in Peninsular Malaysia
P. #knowlesi #malaria 1st isolated/studied Kolkata India 1930s, after it was noticed in blood film from a long-tailed macaque from Singapore. inoculated P. knowlesi-infected blood into 2long-tailed macaques &1 rhesus macaque: fulminant in rhesus & mild infection in long-tailed macaques
#malaria #Plasmodium #knowlesi found in nature in long-tailed & pig-tailed macaques. Was extremely rare in humans until large cluster 2004 Sarawak, Malaysian Borneo. Now seen throughout SE Asia
#plasmodium #knowlesi #malaria SE Asia, ✅travel:/lack of malaria prophylaxis in return travelers. Indistinguishable from P malariae on blood smear exam showing both mature & immature forms in circulation. Unlike p malariae: p knowlesi causes daily fever