MX Beamlines at SLS and SwissFEL

This review examines two decades of continuous development in macromolecular crystallography beamlines at the Swiss Light Source and more.

Discover now: https://ow.ly/MQLM50YwZvG

J Synchrotron Rad #MacromolecularCrystallography #SynchrotronBeamlines #SwissLightSource20

A new macromolecular crystallography endstation, MX-ES, has been established at NanoTerasu, Japan's first fourth-generation synchrotron-radiation facility #NanoTerasu #MacromolecularCrystallography #IntegratedStructuralAnalysisPlatform doi.org/10.1107/S205...

The Fourier transform in analytical science - Nature Reviews Methods Primers The Fourier transform is a mathematical tool for analysing signals that vary in space or time via a transform into the frequency domain. This Primer explores how the Fourier transform is used in analytical science, particularly for spectroscopic data, with an overview of theoretical and experimental considerations.

If you'd like to learn more about #Fouriertransform, after reading the #macromolecularcrystallography Primer, check out this #Primer, highlighting the theory behind the Fourier transform and its applications in mass spectrometry, NMR spectroscopy, and IR spectroscopy.
www.nature.com/articles/s43...

Macromolecular crystallography - Nature Reviews Methods Primers This PrimeView highlights the experimental workflow of macromolecular crystallography - a tool that uses x-ray radiation to determine the electronic structure of biomolecules and their complexes.

And the associated #PrimeView highlights the experimental workflow of #macromolecularcrystallography. 🧬
www.nature.com/articles/s43...

This week's #Primer features a breadth of knowledge and tips for interpreting the diffraction data from #macromolecularcrystallography. There's also an in-depth discussion about the impact of resolution and errors in the Fourier Transform for crystallography. ↘️💠↗️

"UK’s ‘OpenBind’ consortium will use breakthrough experimental technology to generate the world’s largest collection of data [500,000 structures] on how drugs interact with proteins, the building blocks of the body."

Looks like the current diversity & depth of […]

[Original post on xtaldave.net]

Cryo2RT is a high-throughput RT data-collection method from cryo-cooled crystals that reveals unique ligand-binding poses and enables high-throughput fragment-based screening at RT #MacromolecularCrystallography #RoomTemperature #LigandBinding t.co/FZkPd8E0Y0

To make diffuse scattering techniques more accessible, software for data processing called mdx2 has been created that is both convenient to use and simple to extend and modify. #DiffuseScattering #MacromolecularCrystallography #DataProcessing t.co/WhOnF9BH2k