Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made Riboswitch Riboswitches are regulatory RNA structures that modulate gene expression in response to a small molecule. Until now, most efforts to design ligand analogs were motivated by their potential antibiotic ...

Paper alert, some news on our #syntheticbiology activities. You can find out paper on the TPP #riboswitch activator at pubs.acs.org/doi/10.1021/.... And even better, you can order the compound for free on #boehringer 's #opnMe platform at www.opnme.com/molecules/tp....

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