dx clinical. #rickettsia #parkeri Dx confirmed by 4x or greater rise in antibody titer between acute & convalescent-phase serum samples. Acute-phase specimens are taken during 1st week of illness &convalescent-phase samples are generally obtained 2–4 weeks after the resolution of illness.
gulf coast tick: Post-tick bite antibiotic prophylaxis is not recommended to prevent rickettsial infection. Observe clinically for clinical sx for 2 wks post bite #rickettsia #parkeri
#rickettsia #parkeri Doxycycline is the treatment of choice and should be started emprically based on clinical suspicion. Dont wait for lab confirmation.
#rickettsia #parkeri eschar f/b fever, muscle pain, headache & rash. Rash: maculopapular or vesicular eruptions on trunk/ extremities. Regional lymphadenopathy is detected in 25% of pts. GI sx are rare. Pts often develop mild transaminitis, mild leukopenia & less frequently mild thrombocytopenia.
mmwr cases of #rickettsia #parkeri seen in #amblyomma ticks pmc.ncbi.nlm.nih.gov/articles/PMC...
Dx: serology, immunochemistry, PCR of culture from skin biopsy or eschar swab #parkeri #rickettsia
R #parkeri aka American Boutonneuse Fever. Lone star or Gulf coast ticks (Amblyomma maculatum). Generally SE US/Gulf Coast but mmwr cases from Arizona. Also Argentina, Uruguay, Brazil. Sx: HA, myalgia, skin faint salmon rash, single/multiple eschar
eschar followed by fever & rash is highly suggestive of rickettsial spotted fever. #Rickettsia #parkeri, a tick-borne infection that occurs in the mid & South Atlantic states, S Central & Gulf coast states of USA, as well as in S America.
Vector of the Month: #Amblyomma #ovale, a #Neotropical #tick transmitting #Rickettsia #parkeri, authored by Barbara Weck, Álvaro Faccini-Martínez, Marcelo Labruna & Sebastián Muñoz-Leal @niaidnews.bsky.social @uspoficial.bsky.social @udeconcepcion.bsky.social
authors.elsevier.com/a/1lPlh5Eb1x...