Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Non-Natural Photoenzymatic Radical Reactions Selective radical chemistry poses fundamental challenges for modern catalysis. Non-natural photoenzymes, most prominently flavin-dependent “ene”-reductases, have recently emerged as appealing systems ...

Excited to share our latest work on elucidating the molecular origins of three types of selectivity in non-natural #photoenzymatic radical reactions using #compchem, including multiscale simulations and enhanced sampling, just published in #J_A_C_S! pubs.acs.org/doi/10.1021/...

Cool to have Todd Hyster from Princeton University with us today at NUS Chemistry in Singapore. Photo credits: Jie Wu, Yu Zhao. #photoenzymatic #catalysis