Also at #preprinthub1, Soham De from the University of Oxford will present a #preprint from Dr. Samuel G. Katzs' lab about the efficacy of nanobody MET CAR-T cells in solid tumours.

www.biorxiv.org/content/10.6...

This week at #preprinthub1, Michelle Adler from Mt.Sinai will present a preprint from Dr. Cittelly's lab about how estradiol reprogrammes microglia to create an immuno-suppressive niche permissive to brain metastasis in breast cancer.

biorxiv.org/content/10.6...

Also in #preprinthub1, Bhavya Singh from Mt.Sinai presented a preprint from @belkaidlab.bsky.social about how microbiota-dependent IFN-L controls uterine and placental immunity.

www.biorxiv.org/content/10.6...

This week in #preprinthub1, Qin Lou from MD Anderson Cancer Center presented a preprint from Dr. Kimberly McCall's lab about how phagocytosis deficient glia display phagosome processing defects and macrophage recruitment to the brain of Drosophila melanogaster.

www.biorxiv.org/content/10.6...

Also today in #preprinthub1 Preya Patel from the University of Toronto will present a preprint from the Fuchs lab about how immune cells adapt to distinct stem cell niches to govern tissue homeostasis.

biorxiv.org/content/10.6...

Today in #preprinthub1 Guillaume Trusz from MD Anderson will present a preprint from the Kornfeld and @lab-singhal.bsky.social labs on how NR4A1 limits CD8+ T Cell effector responses and protection in tuberculosis.

biorxiv.org/content/10.6...

This week in #preprinthub1, Aislinn Keane from Mt.Sinai will present a preprint from Patrick Süß lab titled "Csf1r-mediated depletion of midbrain microglia prevents dopaminergic neuron loss during chronic colitis"

biorxiv.org/content/10.6...

Also today at #PreprintHub1, Frederika Rentzeperis from Mt.Sinai will present a #preprint by Xueping Zhu from Professor Sokol's lab on how "Sensory neuronal mTORC1 signaling establishes neuroimmune memory that initiates allergic immunity"

www.biorxiv.org/content/10.1...

Today at #PreprintHub1, Sara Lamorte from the University of Toronto will present a #preprint by @diniscalado.bsky.social, titled “Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis"

www.biorxiv.org/content/10.1...

Intratumoral Treg ablation is sufficient to mediate tumor control systemically without autoimmunity Regulatory T cells (Tregs) infiltrate most tumors, yet whether they suppress immune responses directly within tumor tissues is not clear. We used intratumoral (IT) delivery of diphtheria toxin (DT) in...

Also tomorrow in #PreprintHub1, Mehdi Chaib from MD Anderson will present a #preprint from the DuPage lab about how intratumoral Treg ablation is sufficient to mediate tumor control without systemic autoimmunity.
www.biorxiv.org/content/10.1...

Tomorrow in #preprintHub1, Meredith Ramba from
Mt.Sinai will present a #preprint from @maxkonigmd.bsky.social about targeting autoreactive B cells in systemic lupus erythematosus using anti-9G4 idiotope synthetic immune receptor T cells.
biorxiv.org/content/10.1...

The gut microbiota directs vitamin A flux to regulate intestinal T cell development The intestinal microbiota shapes adaptive immunity, but the mechanisms remain incompletely defined. Here, we show that the microbiota initiates the movement of retinoids—dietary vitamin A derivatives ...

Also tomorrow from #PreprintHub1 Shelley Herbrich from MD Anderson will present a #preprint from @LHooperLab on how the gut microbiota regulates intestinal T cell development.

www.biorxiv.org/content/10.1...

Tomorrow #PreprintHub1 is starting for the 2025-2026 season! Laura Rosenberg from Mount Sinai will present a #preprint by the @BelkaidLab on how endogenous retroelements promote tolerance to dietary antigens.

www.biorxiv.org/content/10.1...

We continue this endeavor with two hubs: #preprinthub1 scientists are based in @ox.ac.uk @sinaiimmuno.bsky.social @mdanderson.bsky.social @karolinskainst.bsky.social & University of Toronto; #preprinthub2 at Medical University of Vienna, @mdc-berlin.bsky.social, Charité and Ragon Institute. 🫡