Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity Guidance of nascent axons to their targets is mediated by attractive and repulsive cues that activate receptors on the axonal growth cone.

Our #nervoussystems rely on organized #axonguidance. In a new review paper, IPI and Brown researchers showcase the growing body of #extracellularinteractome studies that evidence new #receptorcomplexes for axon guidance and reveal extensive #signalcrosstalk.