Rothia spp. infective endocarditis: A systematic literature review To describe the epidemiological, clinical, microbiological, and therapeutic features and outcomes of Rothia infective endocarditis (RIE) and extracard…

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#Rothia generally susceptible to penicillin/ampicillin, cefotaxime, imipenem, linezolid, rifampin & vancomycin.
-Frequently resistant to clindamycin, AG, tmp-smx, FQ.

Risk factors for #Rothia injection drug use, cardiac valve disease, prosthetic devices. Infections: bacteremia, endovascular infection, CNS infection, ocular infection, B&J infection, pulmonary infection, biliary tract infection, SSTI

#rothia mucilaginosa normal inhabitant of human oral cavity & respiratory tract. Infrequent pathogen, mostly in immunocompromised hosts (cancer, severe neutropenia, HIV, alcoholism, diabetes mellitus & chronic liver disease)

#Rothia mucilaginosa is increasingly recognized as an emerging opportunistic pathogen associated with prosthetic device infections. Gram-positive cocci, catalase negative, sticky “staph-like” colonies whitish to gray in color, nonhemolytic, smooth, and round

#Rothia mucilaginosa endocarditis