#staphylokinase

Concentration‐dependent dimerization of staphylokinase variants with engineered surface charges Staphylokinase (SAK) is a promising third-generation thrombolytic protein, but its clinical potential is limited by immunogenicity and stability concerns. The conformational and colloidal stabilities....

New paper accepted in 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗦𝗰𝗶𝗲𝗻𝗰𝗲! 🧬 We explored how engineered surface charges and concentration-dependent dimerization shape the stability of #staphylokinase (SAK) variants.

Huge thanks to our collaborators at P. J. Safarik University! 🇸🇰

Read here: onlinelibrary.wiley.com/doi/10.1002/...