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Posts by AMYPAD

The word NEWS written in gold on black metal blocks against a sparkly background. Image by enterlinedesign via Shutterstock.

The word NEWS written in gold on black metal blocks against a sparkly background. Image by enterlinedesign via Shutterstock.

🗞️ Read the February IHI newsletter: link.europa.eu/HfTKq7
🤝 Our director on what makes a good public-private partnership
🚀 An interview with a young researcher on how working in our @imi-amypad.bsky.social project shaped her career
👋 New projects Cities@Heart & PROBE
#HorizonEU #health #research

1 month ago 2 1 0 0
Today is the International Day of Women and Girls in Science, and we're shining the spotlight on Ariane Bollack, who took part in the AMYPAD project as a PhD student. We asked her how taking part in the PPP shaped her career.

Today is the International Day of Women and Girls in Science, and we're shining the spotlight on Ariane Bollack, who took part in the AMYPAD project as a PhD student. We asked her how taking part in the PPP shaped her career.

♀️ Today is the #InternationalDayofWomenandGirlsinScience! 🧠 Meet Ariane Bollack, a former PhD student from the AMYPAD project who's now working in industry. We asked her how the PPP shaped her career & what advice she has for young researchers 👉 link.europa.eu/K6GPPp
#WomenInScience #WomenInSTEM

2 months ago 9 2 0 1
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🎓 Meet Alba Martos Sánchez. She is a full-time PhD student at @barcelonabeta.bsky.social, doing some research in the early-stages of #Alzheimer’s disease.

👉 Read more: amypad.eu/news/recent-...

2 months ago 3 2 1 0
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🎉 Congratulations Dr. Sophie Mastenbroek on successfully defending her PhD cum laude yesterday in Amsterdam 🎓

🌟Wishing Sophie continued success in the exciting journey ahead!

www.amsterdamumc.org/en/research/...

3 months ago 1 1 0 0
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🎓 Meet Prithvi Arunachalam. He is a PhD candidate at Amsterdam UMC, where he contributes to research initiatives including AMYPAD and Euro-PAD.

👉 Read more: amypad.eu/news/recent-...

3 months ago 3 1 0 0
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Implementing robust amyloid PET quantification in multi‐center studies: AMYPAD approach to address data acquisition, processing, interpretation and data sharing challenges INTRODUCTION Amyloid-positron emission tomography (PET) is pivotal to Alzheimer's management, with the Centiloid standardizing measurements across tracers. AMYPAD trials (Diagnostic and Patient Mana...

👉 NEW AMYPAD paper presenting the AMYPAD approach to address data acquisition, processing, interpretation and data sharing challenges!

Congratulations to all authors👏

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

3 months ago 2 0 0 0
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Today, @ihieurope.bsky.social hosted a webinar on regulatory impact. On behalf of AMYPAD, Gill Farrar presented how we succeeded in the Biomarker Qualification Opinion application for our Centiloid work!

#RegulatoryScience #HorizonEurope #ResearchImpact

4 months ago 2 0 0 0
Meet the speakers: Ralf Herold, Thorsten Vetter, Silvy Da Rocha Dias, Christina Giannakou,  Pierpaolo Moscariello and Oriane Blanquie from the EMA, Gill Farrar from GE Healthcare, Pieter Annaert from KU Leuven and BioNotus, and Marco Viceconti and Giorgio Davico from the University of Bologna

Meet the speakers: Ralf Herold, Thorsten Vetter, Silvy Da Rocha Dias, Christina Giannakou, Pierpaolo Moscariello and Oriane Blanquie from the EMA, Gill Farrar from GE Healthcare, Pieter Annaert from KU Leuven and BioNotus, and Marco Viceconti and Giorgio Davico from the University of Bologna

🚨 Happening today! Join us at 14:00 for Regulatory impact: what it is & how to achieve it with your IHI project. Hear from EMA regulators & past projects about their experiences, advice & top tips for achieving maximum impact. Don't miss it! 👉 link.europa.eu/vGdQrY
#RegulatoryScience #HorizonEurope

4 months ago 3 2 0 0
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Amyloid PET predicts atrophy in older adults without dementia: Results from the AMYPAD Prognostic & Natural History study The impact of amyloid-β (Aβ) accumulation on regional brain atrophy in preclinical Alzheimer’s disease (AD), and its interaction with risk factors lik…

📣New paper out on the role of cerebral amyloid-β in cortical, allocortical and subcortical atrophy in (mostly) cognitively unimpaired individuals from the AMYPAD Prognostic and Natural History Study!

Congratulations to all authors👏

www.sciencedirect.com/science/arti...

4 months ago 5 2 0 0

Interested to learn how to maximise your project’s regulatory impact? Register for this online event hosted by @ihieurope.bsky.social ⤵️
www.ihi.europa.eu/news-events/...

Gill Farrar will highlight the regulatory value that our AMYPAD Biomarker Qualification Opinion brought to the amyloid PET field

5 months ago 1 0 0 0
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Complementary utility of plasma biomarkers and Aβ‐PET for diagnosis, risk‐stratification, and treatment monitoring in Alzheimer's disease With the rapid development of blood biomarkers (BBMs) related to amyloid-β (Aβ) pathology in Alzheimer's disease (AD), the question arises whether these can replace the accepted reference standard, ...

📢 Check out this perspective review, highlighting the advancements brought by blood biomarkers in Alzheimer's disease🧠🩸

doi.org/10.1002/alz....

6 months ago 2 1 0 0
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We were pleased to join an exciting symposium during #EANM25 last week in Barcelona focused on advancing early diagnosis with PET imaging and biomarkers.

Lyduine Collij shared AMYPAD insights and spoke alongside Prof. Dr. Alexander Drzezga and Prof. dr. Silvia Morbelli.

amypad.eu/news/recent-...

6 months ago 0 0 0 0
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Cortical thickness subtypes in cognitively unimpaired individuals: Differential network and transcriptomic vulnerability to cortical thinning INTRODUCTION The emergence, stability, and contributing factors of Alzheimer's disease (AD) gray matter subtypes remain unclear. METHODS We analyzed data from 1323 individuals without a diagnosis ...

📢 NEW paper out in Alzheimer's & Dementia, using data from the AMYPAD Prognostic and Natural History Study!

Congratulations to all authors 👏

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

6 months ago 3 3 0 0
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🚀 We’re pleased to announce the release of the latest edition of our newsletter, featuring the release of the AMYPAD raw dataset, highlights from the Euro-PAD symposium and new papers!

👉 Read the full newsletter here: mailchi.mp/e602ab237ff7...

6 months ago 1 1 0 0
Harmonizing genotype array data to understand genetic risk for brain amyloid burden in the AMYPAD PNHS Consortium INTRODUCTION We sought to harmonize genotype data from the predementia AMYPAD (Amyloid Imaging to Prevent Alzheimer's Disease) Consortium, compute polygenic risk scores (PRS), and determine their as.....

📣NEW AMYPAD out!

The genetic data harmonisation manuscript for the AMYPAD consortium is online in Alzheimer's & Dementia!

Authors provide a detailed pipeline for genotype array data QC, imputation, harmonisation, and PRS computation⤵️

doi.org/10.1002/alz....

7 months ago 1 1 0 0
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📣 #AAIC25 is around the corner!

Whether you’ll be on-site in Toronto or joining online, don’t miss the AMYPAD presentations 👇

For more information about the conference, please visit: aaic.alz.org

8 months ago 1 0 0 0
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Utility, Costs and Cost‐Utility of Amyloid‐PET in the Diagnostic Process of Memory Clinic Patients: A Trial‐Based Economic Evaluation From AMYPAD‐DPMS Background Amyloid positron emission tomography (PET) is instrumental in achieving an accurate diagnosis and may help to limit health-seeking behavior. Currently, amyloid-PET is not routinely used i...

📢 NEW AMYPAD paper out in European Journal of Neurology assessing the cost-utility of early versus no amyloid-PET in the diagnostic work-up of memory clinic patients after 6 months. @ihieurope.bsky.social

Congratulations to all authors 👏

doi.org/10.1111/ene....

9 months ago 0 1 0 0
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This past two days, we hosted the Euro-PAD symposium to discuss the latest advancements in neuroimaging and biomarkers for #Alzheimer’s disease, as well as to share updates from the Euro-PAD initiative over the past year. ⤵️

www.barcelonabeta.org/en/news/news...

10 months ago 3 1 1 0
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📣Yesterday and today, the Euro-PAD community convened in Barcelona for a scientific symposium hosted by @barcelonabeta.bsky.social.

👉Almost 100 participants gathered to discuss the latest advancements in neuroimaging and biomarkers for Alzheimer’s disease!

amypad.eu/news/recent-...

10 months ago 4 1 0 0
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This morning, before the symposium, we held two parallel workshops, one led by #BBRC researchers focused on fluid biomarkers and the other led by
@acealzheimercenter.com focused on clinical trials

10 months ago 4 2 0 0
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Today and tomorrow we are hosting the EuroPAD 2025 symposium!

#EuroPAD seeks to enhance and extend late-stage biomarker cohorts focused on Alzheimer’s, with the specific aim of establishing the most extensive and deeply phenotyped longitudinal cohort of at-risk individuals.

10 months ago 4 1 1 0

📢 JUST PUBLISHED: Paper in @natrevdrugdiscov.nature.com on how to maximise #RegulatoryImpact from public-private partnerships, co-authored by IHI’s Nathalie Seigneuret. Check out 3 examples to follow from C-Path & @imi-amypad.bsky.social
👇 Read it below 👇
#IHITransformingHealth #RegulatoryScience

10 months ago 2 1 0 0
Delivering regulatory impact from consortium-based projects Multiple consortia have been established in the past two decades with the aim of tackling roadblocks in the development of medical products, often by developing new tools to support decision making by...

📣New paper out highlighting lessons learned that could help maximise the regulatory impact of consortium-based projects.

C-Path and AMYPAD are featured as examples of projects that have achieved regulatory successes

👉https://www.nature.com/articles/d41573-025-00098-8

10 months ago 1 0 0 0
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Quantification of baseline amyloid PET in individuals with subjective cognitive decline can identify risk of amyloid accumulation and cognitive worsening: the FACEHBI study - European Journal of Nucle... Purpose Amyloid PET imaging is capable of measuring brain amyloid load in vivo. The aim of this study is to assess the relationship of the baseline amyloid with its accumulation over time and with cog...

NEW paper out entitled "Quantification of baseline amyloid PET in individuals with subjective cognitive decline can identify risk of amyloid accumulation and cognitive worsening: the FACEHBI study"

Congratulations to all authors 👏

Check it out now⤵️

link.springer.com/article/10.1...

11 months ago 0 1 0 0
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📢Exciting news! We're pleased to announce that the AMYPAD raw dataset is now available for data access requests on the Alzheimer's Disease Data Initiative's Workbench!

➡️ Visit the AMYPAD website for more information: amypad.eu/data/

1 year ago 1 1 0 0
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👉Leo Pieperhoff presented findings from the AMYPAD PHNS study at #ADPD2025 today!

The harmonised data are available on the #ADWorkbench of the Alzheimer’s Disease Data Initiative. Interested to learn more? Visit Booth 16 of the Alzheimer’s Disease Data Initiative at #ADPD2025!

1 year ago 0 0 0 0
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🧠 #ADPD2025 DAY 2!

Join us in Room Hall F2 today at 13:50 for the symposium “WHITE MATTER ALTERATIONS”.

Leonard Pieperhoff will be presenting AMYPAD results “Grey/White Matter Contrast Alterations Precede Amyloid Positivity and Atrophy Markers.”

Don’t miss his insightful presentation 🙌

1 year ago 2 0 0 0
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🚨#ADPD2025 is officially underway!

This morning Mario Tranfa, Luigi Lorenzini and Emma Luckett presented data from the AMYPAD, EPAD and Euro-PAD consortiums!

Natàlia Vilor Tejedor also presented the #ADWorkbench at the session hosted by the Alzheimer's Disease Data Initiative!

1 year ago 1 0 0 0
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✨ Today marks the start of #ADPD2025 in Vienna!

If you're attending the conference, don’t miss the AMYPAD, EPAD and EUROPAD-related talks.

We hope to see you there to catch up on our latest advancements 🙌

1 year ago 2 2 0 0
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👉 Earlier today, we were pleased to present insights from the AMYPAD project at #ECCN2025 during a satellite symposium, sponsored by Life Molecular Imaging!

Thanks to everyone who joined us and contributed to the discussion ☺️

1 year ago 2 0 0 0