Summer Student Intern (Canadian Centre for Computational Genomics)

bioinformatics.ca/jobs/summer-...

Great lab to go learn #bioinformatics, in the great city of #Montréal! #summerJob #summerintern

Ten simple rules for coordinating a large digital health project: Perspectives from EU and implications for global contexts Coordinating a large-scale digital health project requires a unique mix of scientific leadership, administrative skill, and human sensitivity. Drawing from our experience leading CAPABLE, a European H...

From @plos.org #Computational #Biology | Ten simple rules for coordinating a large #digital #health project: Perspectives from EU and implications for global contexts | #Education #Bioinformatics #Research #Healthcare #PLOSCBTSR 🧬 🖥️ 🧪 🔓
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journals.plos.org/ploscompbiol...

Biology struggles with the “species problem”, which refers to the fact that no single definition of species seems to work for all living things.

Linguists have a similar problem with the definition of language. Where does one language end and another begin?

Marco Rubio is reportedly saying Maduro will stand trial in US courts.

Which means it’s now the US administration’s position that US courts can hold foreign presidents, but not the US president, accountable for crimes.

Mamdani: For too long, those fluent in the good grammar of civility have deployed decorum to mask agendas of cruelty

When It Happens Our 14th most-read article of 2025. - - -It’s been so long, you sometimes forget that eventually, IT will HAPPEN. It’s impossible to say when IT w...

"It’s fair to say that IT will happen. But you also prepare for the possibility, even if unlikely, that IT won’t HAPPEN for a long time. Some of you may not last long enough to see IT HAPPEN, which is RICH." #McSweeneysTop25of2025

The UCSC Genome Browser database: 2026 update Abstract. Now in its 25th year of operation, the UCSC Genome Browser (https://genome.ucsc.edu) provides a central location for researchers around the world

From the @genomebrowser.bsky.social team in @narjournal.bsky.social #NARDatabaseIssue | The UCSC Genome Browser database: 2026 update | #Bioinformatics #Genomics #Database #OpenScience 🧬 🖥️🧪🔓
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academic.oup.com/nar/advance-...

4-panel vertical comic. (1) 100 Years Ago [two people standing next to bicycle with small car nearby] PERSON 1: It’s too dangerous riding a bike with these cars around. I should get a car, too. (2) 50 Years Ago [two people between smaller car and bigger car] PERSON 2 with short hair: Small cars are less safe in collisions with larger vehicles, so I should get a bigger one. (3) Today [two people between big car and even bigger car] PERSON 1: Everyone has huge SUVs now. If I don’t get the biggest one, I’m putting my family at risk. (4) Soon [two people next to large armored car with spiked clubs attached] PERSON 2: If I don’t install more whirling spike clubs, I’ll be destroyed by all the other drivers who...

Car Size

xkcd.com/3167/

Comic. PERSON 1 with white hat: How tall are you? PERSON 2: 5ft 24cm [caption] When switching to metric, make the process easier by doing it in steps.

Metric Tip

xkcd.com/3164/

This reminds me of those Star Wars guides where they used to break down all the different types of Imperial Stormtroopers...

Jane Goodall, ethologist and conservationist, has died. She was 91

"Harvard can't use race as a factor in admissions, but ICE can use race as a factor in detentions" is a retrenchment essentially to a pre-Civil War understanding of the Constitution. It's vanishingly few steps removed from "Latinos have no rights which the white man is bound to respect."

mRNA tech is some of the coolest, most powerful, most promising scifi shit humans are currently doing. They are being investigated to help with cancers, autoimmune diseases, M.S., stroke recovery, heart disease, diabetes, arthritis, and high cholesterol.

Shredding coconuts is one of 20-year-old Eurasian eagle owl Forrest’s favorite enrichments behind the scenes, and he’s not shy about letting you know it. From dramatic screeches to full-on head swivels, Forrest brings the drama just in time for #OwlAwarenessDay. 🦉

This is beyond unethical. Worse than a Black Mirror episode. I hope the backlash is swift and they never allow AI to “speak” for the dead ever again.

Low-dose metformin requires brain Rap1 for its antidiabetic action Metformin lowers blood glucose by inhibiting Rap1 in ventromedial hypothalamic neurons that regulate glucose balance.

Metformin, the first line drug for Type 2 diabetes, has been used for 60 years without a clearcut mechanism of action. It turns out it's not just reducing glucose output from the liver. Metformin also works via the brain www.science.org/doi/10.1126/...

apple is as desperate as the rest of us for the ai hype bubble to burst so investors will fuck off asking about its ai strategy

Silicon Valley's Push Into Transportation Has Been a Miserable Failure The titans of tech brought plenty of disruption to our broken transportation system but delivered little in the way of innovation.

“Elon Musk admitted to his biographer that the reason the Hyperloop was announced—even though he had no intention of pursuing it—was to try to disrupt the California high-speed rail project to get in the way of that actually succeeding.” — @parismarx.com in @gizmodo.com

He’s always been this way.

Made-to-order DNA goes big: new tech doubles size of custom genetic sequences Enzyme-based techniques and refinements in organic chemistry ease the generation of extended DNA sequences.

A technology feature in Nature describes how enzyme-based techniques and refinements in organic chemistry are easing the generation of extended DNA sequences. 🧬 🧪

Paris cycling numbers double in one year thanks to massive investment and it's not stopping The report delves into the nuances of Parisian cycling culture, exploring the vibrant community of riders who navigate the city's streets

Paris urban biking DOUBLED in just one year.

“Cycling in Paris has transcended mere trendiness; it’s become a fundamental aspect of the city’s identity. Despite challenges like inclement weather, cyclists continue to flock to the streets, setting new records and reshaping the urban landscape.”

The Running Novelist If I wanted to have a long life as a writer, I needed to find a way to stay in shape.

Haruki Murakami was about to turn 30 when a thought occurred to him: “You know what? I could try writing a novel.” Then he realized, “If I wanted to have a long life as a novelist, I needed to find a way to stay in shape.”

I don’t think anyone is prepared for what they just did w/ ICE.

This is not a simple budget increase. It is an explosion - making ICE bigger than the FBI, US Bureau of Prisons, DEA,& others combined.

It is setting up to make what’s happening now look like child’s play. And people are disappearing.

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

A white mug with the Ursula K. Le Guin Prize for Fiction logo holds a spray of lavender next to a stack of the eight books shortlisted for this year's prize: North Continent Ribbon by Ursula Whitcher Remember You Will Die by Eden Robins The City in Glass by Nghi Vo Archangels of Funk by Andrea Hairston The Sapling Cage by Margaret Killjoy Rakesfall by Vajra Chandrasekera The West Passage by Jared Pechaček Blackheart Man by Nalo Hopkinson

We're thrilled to present the shortlist for the 2025 Ursula K. Le Guin Prize for Fiction:

The Fiddle and the Drum YouTube video by Joni Mitchell - Topic

"The Fiddle and the Drum" - (1969) Joni Mitchell

Relevant today as when it was originally released.
youtu.be/H7YQLMH7wL4?...

This War Will Destabilize The Entire Mideast Region And Set Off A Global Shockwave Of Anti-Americanism vs. No It Won’t

theonion.com/this-war-wil...

What’s Happening to Reading? For many people, A.I. may be bringing the age of traditional text to an end.

For some, the traditional mode of reading—intense, extended, beginning-to-end encounters with carefully crafted texts—has become almost anachronistic. How will A.I. transform the ways in which we read?

Photo of the first edition of Joyce’s Ulysses, white text on blue cover, “Ulysses by James Joyce”. It’s a chunky book.

A little colour note for Bloomsday, the anniversary of Leopold Bloom’s adventures across Dublin. James Joyce requested a very specific blue for the cover of Ulysses: the blue of the Greek flag, a nod to Homer & Ancient Greece, and a token of the country that Joyce believed brought him good luck…

In a comic strip panel, person in a red shirt walks through a sunlit forest. The text says "Sometimes I go looking for a tiny part of the universe." "This part only takes up as much space as: half an apple, a salt shaker, or 2 ping pong balls." Each of these items is shown. Galaxies and stars swirl as the text says "But somehow, in an unfathomably huge universe," and then there's a complex mess of forest leaves, with one tiny Wilson's warbler in one corner, and the text says "this one tiny part" There's a close up of the warbler, blazing yellow against a sparkly yellow background, and the text says "can fill up my whole heart."

Tiny part.