Personal #CIBERBBN en la @upv.es desarrolla un biosensor rápido y de bajo coste para detectar #tuberculosis activa 🔎🔬

Más info en ➡️ www.upv.es/noticias-upv... @cipfvalencia.bsky.social

🔬 El #CSIC e #ISGLOBAL firman un acuerdo de colaboración para reforzar la investigación en salud

➡️ Ambas entidades promoverán proyectos de investigación y asesoramiento, así como seminarios y jornadas especializadas

👉 http://tiny.cc/2ll1101

🧬 pathotypr is now on Bioconda! @pathogenomics.bsky.social
conda install -c bioconda pathotypr

Alignment-free lineage classification & drug resistance genotyping from WGS. Works with any pathogen bring your own SNP markers.
⚡ Rust, ~1s/sample
🖥️ CLI + GUI
🔗 github.com/PathoGenOmics-Lab/pathotypr

Un momento dulce compartiendo la mona de Pascua con los compañeros. Tradiciones que unen y alegran el día. @i2sysbio.es @paururo.bsky.social @ahmig.es

In benchmarking, Pathotypr showed very high concordance with phylogenetic lineage assignment and achieved very fast analysis speeds, making near real-time TB genomic surveillance feasible even on standard desktop hardware. It is available as both a command-line tool and an easy desktop GUI.

The toolkit integrates multiple modules in one workflow:
Train / Predict for lineage classification, Split FASTQ / Classify for genotyping from reads or assemblies, and Match Ref to identify the closest reference genome for each sample.

Pathotypr supports all 14 currently recognised MTBC lineages, including human-adapted lineages L1-L10 and animal-adapted clades A1-A4. It also incorporates recently described diversity such as L10, helping standardise TB genomic surveillance across settings.

GitHub - PathoGenOmics-Lab/pathotypr: Genome classificator using machine learning and SNP markers. Genome classificator using machine learning and SNP markers. - PathoGenOmics-Lab/pathotypr

Excited to share Pathotypr with @paururo.bsky.social, our open-source toolkit for rapid, harmonised MTBC lineage assignment and drug-resistance genotyping from both genome assemblies and raw reads. @i2sysbio.es. tool github.com/PathoGenOmic.... preprint: doi.org/10.64898/202...

Interior del laboratorio BSL-3 durante trabajo rutinario con muestras de tuberculosis

🔬 Hoy es el Día Mundial de la Tuberculosis.

Esta imagen refleja algo que rara vez se ve: las horas dentro de un BSL-3, la bioseguridad, el trabajo silencioso detrás de cada avance.

@i2sysbio.es @pathogenomics.bsky.social

The “curse of interdisciplinarity”:
Fields like bioinformatics fall between the cracks in grant evaluation.
🧬 For bios: Too little mechanistic validation
🧮 For math: Not enough new theory
💻 For computing: “Just” applied computing
Interdisciplinarity is essential, but evaluation hasn’t caught up.

🔬 World TB Day 2026 — Behind the mask, inside BSL-3.

Our team works daily to understand M. tuberculosis evolution, resistance & transmission through genomics.

TB still kills 1.25M people/year. Research matters.

@i2sysbio.es

#WorldTBDay #EndTB #Tuberculosis

El Instituto de Biología Integrativa de Sistemas celebra su décimo aniversario con un acto conmemorativo en el Parc Científic de la Universitat de València

www.i2sysbio.es/communicatio...

@i2sysbio.es

Happy Bioinformatics Day!🧬💻Celebrate the power of data for understanding life at every level. In @pathogenomics.bsky.social we combine experiments with bioinformatics to understand bacterial evolution, virulence, and infection dynamics. #SoyBioinformatica @paururo.bsky.social @ahmig.es @i2sysbio.es

@i2sysbio.es 10th Aniversary Celebration, science and fun!

Proud to celebrate 10th anniversary of @i2sysbio.es 🎉 Being part of a community dedicated to discovery, collaboration, and advancing science is truly inspiring. Grateful to contribute, learn, and grow alongside such passionate colleagues. Here’s to many more years of knwledge and impact! 🔬✨

¿Quieres un impulso a tu formacion investigadora🔬? En
@i2sysbio.es ofertamos beca JAE Intro @amrhubcsic.bsky.social al. Plan formativo "Frenar la adquisición de resistencia en bacterias patógenas💊". 6 meses remuneración de 600 €/mes. Aplica antes del 10 marzo en www.convocatorias.csic.es/convoca/

🚀 #ESM2026 registration is open! 46th Annual Congress of the European Society of Mycobacteriology.
📍 Verona, Italy | 🗓️ 22–25 June 2026
🔗 www.esmycobacteriology.eu/event-home

Useful tool from the PathogenOmics Lab thanks to @paururo.bsky.social: get_mnv v1.0.1 🧬

ComFuturo Fourth Edition: ComFuturo iAGE Call - FGCSIC The Fundación General CSIC (FGCSIC) launches the fourth edition of its ComFuturo programme: ComFuturo iAGE, a postdoctoral initiative co-financed by the Marie Skłodowska-Curie Actions COFUND scheme of...

🚨JOB ALERT

Dr. Buceta at @i2sysbio.es welcome applications for 36-month postdocs on:

👉 Mechanical markers of tissue dysfunction due to ageing – digital twins & machine learning

Details here: fgcsic.es/convocatoria...
📩 Contact javier.buceta@csic.es to shape your proposal!

@epimechfc.bsky.social

Come and join us in Valencia next January for the meeting of the Spanish Society of Evolutionary Biology. Deadline for abstracts October 22nd. sesbe2026.es/registration/

Back from #MycoVLC2025 after presenting our M. tuberculosis work. Huge thanks to Mireia for stellar mentorship. Proud of my @pathogenomics.bsky.social mycolegas for standout posters. Energized to turn ideas into results. #TB #TBResearch @i2sysbio.es

Mireia Coscollà, CSIC, I2SysBio

Then, we Mireia Coscollà ( @pathogenomics.bsky.social ), from I2SysBio ( @i2sysbio.es ) talked about compatibility between hosts in bacterial infections.

GitHub - PathoGenOmics-Lab/fstic: Calculates pairwise distances between samples using alelle frequencies Calculates pairwise distances between samples using alelle frequencies - PathoGenOmics-Lab/fstic

From fàstic to fantastic population genetics with @pathogenomics.bsky.social :announcing Fstic a high-performance Rust CLI that computes N×N genetic distance matrices from VCFs or allele-frequency tables at scale. (fàstic=Valencian/Catalan for annoyance)Code: github.com/PathoGenOmic... @i2sysbio.es

Interview of Tomás Matus, PI of the Transcriptional Orchestration of plant metabolism group YouTube video by Institute for Integrative Systems Biology I2SysBio

El #I2SysBio (@csic.es - @uv.es) ha lanzado una serie de vídeos sobre los diferentes grupos de investigación en este centro. El nuevo video es sobre el grupo Orquestación transcripcional del metabolismo vegetal de Tomas Matús @jtmatus.bsky.social
🎥🌐 youtu.be/43V4MOtAf4k?...
🧪🧬🖥️ 🌾🌱🍇 #plantscience

Spanish Society Evolutionary Biology meeting January 2026 in the botanical Garden ‪@uv.es‬ in Spain. Registration 200-350€. Preliminary program with confirmed keynote speakers: sesbe2026.es/programme/. Abstract submission until September 15th. sesbe2026.es/abstract/. Come to Valencia and join us!

GitHub - PathoGenOmics-Lab/VIPERA: A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis A Snakemake workflow for SARS-CoV-2 Viral Intra-Patient Evolution Reporting and Analysis - PathoGenOmics-Lab/VIPERA

VIPERA v1.2.1 is here!! 🐍🐍🐍

Our workflow for SARS-CoV-2 intra-patient evolution analysis now fully supports Snakemake 8/9 (with dedicated CI tests), BIONJ trees, richer reports, added config parameters, modular Snakefiles and more! 🧪👉 github.com/PathoGenOmics-Lab/VIPERA

‪@ahmig.es‬ presented the poster "Expanding the scope of evolution reporting and analysis: from intra patient dynamics to outbreaks" at MCEB 2025 in Granada thanks to the funding @bcbhubcsic.bsky.social and ‪@ageinves.bsky.social‬.

A photo of a group of people with the Alhambra in the back

Just back from MCEB 2025 in Granada! I presented our year-long work expanding VIPERA🐍 to help us better track pathogen evolution, here at @pathogenomics.bsky.social - @i2sysbio.bsky.social. I learned so much and returned full of ideas! Thanks to @bcbhubcsic.bsky.social for funding my attendance! 🧪

Today, I2SysBio researchers were busy with #scienceoutreach activities at #Expociencia. Here are photos of the Pathogenomics lab @pathogenomics.bsky.social explaning in a playful way how our immune system works 🧬🖥🦠🧫🧪

Nuestro 4to año superado con creces, #expociencia2025 @pathogenomics.bsky.social @i2sysbio.bsky.social