@caldaslab.bsky.social pleads with @erc.europa.eu to 'correct' this! It would be a strategic mistake! Listen please to @johannajoyce.bsky.social! After all she is President-elect of @helloeacr.bsky.social!

Proud to be part of @hebrewuniversity.bsky.social and to have @caldaslab.bsky.social now based @lautenbergc.bsky.social! Walking the walk!

The Old City!

Don't miss this outstanding conference! @helloeacr.bsky.social

Don't miss this outstanding conference! @helloeacr.bsky.social

PI3K Inhibition in Combination with Tamoxifen in Patients with Metastatic HR+/HER2− Breast Cancer!
This started with the RATHER project, which was part of the EU's FP VII funded (cordis.europa.eu/project/id/2...)
@caldaslab.bsky.social always walked the walk!

aacrjournals.org/clincancerre...

PI3K Inhibition in Combination with Tamoxifen in Patients with Metastatic HR+/HER2− Breast Cancer!
This started with the RATHER project, which was part of the EU's FP VII funded (cordis.europa.eu/project/id/2...)
@caldaslab.bsky.social always walked the walk!

aacrjournals.org/clincancerre...

Cell clones tracked using expressible lentiviral barcodes to analyse cell fate, fitness and state! Amazing work from @nguyenlab.bsky.social and @caldaslab.bsky.social! Walking the walk! We will continue using this approach @lautenbergc.bsky.social based @hebrewuniversity.bsky.social!
Walk the walk!

Cell clones tracked using expressible lentiviral barcodes to analyse cell fate, fitness and state! Amazing work from @nguyenlab.bsky.social and @caldaslab.bsky.social! Walking the walk! We will continue using this approach @lautenbergc.bsky.social based @hebrewuniversity.bsky.social!
Walk the walk!

Single-cell spatial atlas of the aging human breast - Nature Aging The dynamics of breast tissue aging are characterized by imaging mass cytometry of over 500 reduction mammoplasties, revealing nonlinear loss of cellularity and a compositional shift favoring inflamma...

Amazing paper from @hrazaalilab.bsky.social and Sam Aparicio! Single-cell spatial atlas of the aging human breast.
Work from people that walk the walk! Raza Ali is a #Caldasian!

www.nature.com/articles/s43...

@hebrewuniversity.bsky.social

Humbled to be featured @hebrewuniversity.bsky.social where @caldaslab.bsky.social is now based @lautenbergc.bsky.social!
Walking the walk!

international.huji.ac.il/news/Prof-Ca...

Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity - Nature NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer immunity and autoimmunity.

Amazing from Tobias Janowitz and co from @cshlnews.bsky.social published @nature.com!
Great also to see yet another major piece of #BreastCancer research using #METABRIC!!

www.nature.com/articles/s41...

Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity - Nature NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer immunity and autoimmunity.

Amazing from Tobias Janowitz and co from @cshlnews.bsky.social published @nature.com!
Great also to see yet another major piece of #BreastCancer research using #METABRIC!!

www.nature.com/articles/s41...

Deep learning on histopathological images to predict breast cancer recurrence risk and chemotherapy benefit: a multicentre, model development and validation study These findings show that AI applied to routine histopathology can serve as a practical and scalable tool for guiding chemotherapy decisions in hormone receptor-positive, HER2-negative, early breast ca...

This is an excellent paper from our colleagues @technion.bsky.social!
#AI #DigitalPathology #BreastCancer

www.thelancet.com/journals/lan...

Deep learning on histopathological images to predict breast cancer recurrence risk and chemotherapy benefit: a multicentre, model development and validation study These findings show that AI applied to routine histopathology can serve as a practical and scalable tool for guiding chemotherapy decisions in hormone receptor-positive, HER2-negative, early breast ca...

This is an excellent paper from our colleagues @technion.bsky.social!
#AI #DigitalPathology #BreastCancer

www.thelancet.com/journals/lan...

Impactful and pioneering work! Now cited 200 times! A new paradigm: phenogenomic landscapes in cancer. @hrazaalilab.bsky.social @bb-lab.bsky.social @caldaslab.bsky.social
#METABRIC
We were walking the walk on multi-omics already in 2020!!

www.nature.com/articles/s43...

Precancerous niche remodelling dictates nascent tumour persistence - Nature A study investigating the emergence of squamous tumours in the upper gastrointestinal tract of the mouse shows that an initial tumour stress response triggers fibroblasts to remodel the underlyin...

Important work!!

www.nature.com/articles/s41...

This is amazing news! Congratulations to @hrazaalilab.bsky.social based @cruk-ci.bsky.social! I fondly remember his PhD @caldaslab.bsky.social! Raza is a superstar #Caldasian and I will continue to value enormously our scientific exchanges! Raza is also a close friend!

From small beginnings...
Osnat and Viji getting the first breast cancer cell lines @caldaslab.bsky.social going! At our brand new tissue culture room @lautenbergc.bsky.social! Stay tuned for our discoveries @hebrewuniversity.bsky.social!
Walking the walk! Never talking the talk!

A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics - Nature Cancer Hoang et al. developed a deep-learning framework called ENLIGHT–DeepPT that predicts therapy response based on imputed transcriptomics and shows predictive power across patient cohorts and cancer type...

This paper is now Highly Cited according to @clarivate.com! Proud that @caldaslab.bsky.social contributed to it! More to come from us @lautenbergc.bsky.social!

www.nature.com/articles/s43...

A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics - Nature Cancer Hoang et al. developed a deep-learning framework called ENLIGHT–DeepPT that predicts therapy response based on imputed transcriptomics and shows predictive power across patient cohorts and cancer type...

This paper is now Highly Cited according to @clarivate.com! Proud that @caldaslab.bsky.social contributed to it! More to come from us @lautenbergc.bsky.social!

www.nature.com/articles/s43...

Outstanding meeting!
@helloeacr.bsky.social
@carloscaldas1960.bsky.social
@caldaslab.bsky.social

Dinner with colleagues from @technion.bsky.social including Aaron Ciechanover, Nobel Prize of Chemistry in 2004 for elucidating the method that cells use to degrade and recycle proteins using ubiquitin. This after the first day spent at RTICC where I gave two seminars. Fantastic Israel Science!

Fantastic to see at this wonderful conference organised by @shouval.bsky.social and @netaerez.bsky.social at the #Weizmann. And to listen to an excellent talk @shimritmayer.bsky.social from @hrazaalilab.bsky.social! Part of a collaboration with @paulpharoah.bsky.social!
People that walk the walk!!!

The unique and remarkable chappel of @robinsoncollege.bsky.social with stainned glass modern works designed by John Piper and executed by Patrick Reyntiens in the early 1980s! I am very privileged to be a Fellow! The College has been amazing for @caldaslab.bsky.social!

Lobo Antunes RIP
"I suppose I have become a sort of living monument in Portugal. But I come from a family with roots all over the world, so the idea of patriotism is not very strong in me. My country is the country of Chekhov, Beethoven, Velasquez - writers I like, painters and artists I admire."

#Caldasians are everywhere!
@caldaslab.bsky.social always remembering its alumni!

Joint Berlin – Jerusalem Symposium for Cancer Research and Clinical Oncology – 2026

Join us for this outstanding scientific cancer meeting in Berlin
@mdc-berlin.bsky.social!
@caldaslab.bsky.social will be presenting new data from its new lab @lautenbergc.bsky.social!
@hebrewuniversity.bsky.social
@hadassahorg.bsky.social

www.mdc-berlin.de/news/events/...

Fantastic to have our paper:
www.cell.com/cell-reports...,
in this special issue of @cp-cellrepmed.bsky.social on #TME!
@kevinjtu.bsky.social from @caldaslab.bsky.social used deconvolution of bulk RNA expression to characterise the TME of 15,000 breast cancers!!