New Switch for Natural Cell Death Identified

New Switch for Natural Cell Death🧬

Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.

👉 t1p.de/3fxvc

@tum.de @natureportfolio.nature.com

#CellDeath #BNMRZ

Structural basis of apoptosis induction by the mitochondrial voltage-dependent anion channel - Nature Communications TGF-β is a latent complex (L-TGF-β). Latency is conferred by a homodimeric prodomain with a previously undefined domain architecture. Here we define the architecture of the prodomain as domain-swapped...

Check out our recent paper on the role of the #mitochondrial #VDAC channel in #apoptosis induction using an #integrative #structural #biology approach

@tum.de @helmholtzmunich.bsky.social

www.nature.com/articles/s41...

www.tum.de/en/news-and-...

Medicine Nobel goes to three researchers who identified immune system’s security guards Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi

Physics Nobel awarded for macro demonstration of quantum effects John Clarke, Michel Devoret, and John Martinis honored for work demonstrating quantum mechanical tunneling in electrical circuits

This year’s #NobelPrize in Physics honors researchers who demonstrated quantum mechanical effects in electric circuits on a chip. https://scim.ag/46T4qQK

Cellulose-based bilayer films with asymmetric properties for the sealing of tissue lesions - Cellulose To be able to support the complex process of wound closure, a biocompatible material is required that combines suitable adhesiveness and stability with the ability to withstand certain biological chal...

Thanks to colleague Oliver Lieleg and his team at #TUM for being part of this study on cellulose coated bilayer films to support wound healing. doi.org/10.1007/s105...

VDAC2 loss elicits tumour destruction and inflammation for cancer therapy - Nature VDAC2 deficiency elicits uncontrolled IFNγ-induced BAK activation and mitochondrial damage for improved cancer therapy.

Nature research paper: VDAC2 loss elicits tumour destruction and inflammation for cancer therapy

https://go.nature.com/41w9qrS

Maria-Elena Torres-Padilla - Gottfried Wilhelm Leibniz-Preisträgerin 2025 im Portrait Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

#LeibnizPrize 2025: Celebrating Excellence!🎉

👏Yesterday, Prof. Maria-Elena Torres-Padilla officially received the Gottfried Wilhelm Leibniz Prize from the German Research Foundation (DFG)!
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🎥Watch her portrait:
t1p.de/a30vo

@metorrespadilla.bsky.social @dfg.de
#LeibnizPreis

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