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Posts by MiccrobioTAckle
๐งฌ Meet WP1 students!
Their focus? How the microbiome impacts cachexia across cancer types.
๐จโ๐ฌTongkun: cross-cancer multi-omics & ML models for diagnosis
๐ฉโ๐ฌMariem: epidemiology and microbiome of cachexia in colon cancer
๐ฉโ๐ฌMia: microbiome & muscle wasting links
๐ฉโ๐ฌRahma: cytokines & microbiome links
Here we are!
MiCCrobioTAckle is a @Horizoneu.bsky.social doctoral network coordinated by @Leibniz-HKI.de. Our goal is to advance research at the intersection between gut #microbiota and #cancer cachexia.
Follow us for exciting research!
#MSCA
#DoctoralNetworks
#HorizonEurope
Happy #WorldMicrobiomeDay!
Today, our last WP: From discovery to real treatments
๐งฌWP4 turns microbiota science into therapy for cancer cachexia.
Sagnik: designs FMT-based therapies, Anna: leads oral vs. tube-FMT trial, Colleen: builds consortium-in-a-pill
#FMTinAPill #GutMicrobiome #CancerCachexia
#MiCCrobioTAckle #CancerCachexia #GutMicrobiome #PhDResearch #Chronobiology #MicrobiotaMedicine #HorizonEurope #TranslationalScience
WP3 connects the dots:
WP1 finds microbial signatures
WP2 engineers therapeutic strains
WP3 tests causeโeffect in vitro & in vivo
WP4 will bring delivery and translation innovations
Together, advancing microbiota-driven solutions against cancer cachexia!
๐ Parul Sharma (University College Cork, Ireland)
Investigating how gut microbes link with circadian rhythms and whether
microbial therapies can reset biological clocks to ease cachexia.
๐งชLouise Diependaele (DTU, Denmark):Belgian bioengineer developing in vitro models to study gutโhost interactions and therapeutic microbes.
๐ชDevat Kandoriya (UCC, Ireland) Indian Pharmacologist exploring microbial and polyphenol therapies in mouse models, focusing on muscle strength and survival.
๐ฌ Validating MicrobiomeโCachexia Links
In MiCCrobioTAckle, weโre uncovering how microbial imbalances drive cancer cachexia (CC).
Work Package 3 (WP3) dives into causalityโtesting how native or engineered microbes affect cachexia in experimental models.
Meet the WP3 PhD researchers:
๐ป ๐๐ผ ๐ฆ๐๐ป (HKI) โ Using computational tools to optimize strain performance
Weโre creating metabolically rewired strains & consortia to be tested in WP3 models
WP1 โ WP2 โ WP3โฆ and WP4 coming soon
#MiCCrobioTAckle #MicrobiomeTherapeutics #CancerCachexia #GutMicrobiome
#SynBio #SystemsBiology #PhDLife
๐งช ๐๐ป๐ด๐ถ๐ป๐ฒ๐ฒ๐ฟ๐ถ๐ป๐ด ๐ง๐ต๐ฒ๐ฟ๐ฎ๐ฝ๐ฒ๐๐๐ถ๐ฐ ๐ ๐ถ๐ฐ๐ฟ๐ผ๐ฏ๐ฒ๐ | ๐ช๐ฃ๐ฎ
In our project tackling cancer cachexia, WP2 focuses on developing next-gen microbial therapeutics restoring gut barrier function and regulate appetite.
๐๐ ๐ฒ๐ฒ๐ ๐๐ต๐ฒ ๐๐๐๐ฑ๐ฒ๐ป๐๐:
๐ฌ ๐๐ฑ๐ฎ๐บ ๐๐ฒ๐ป๐ผ๐ณ๐ฎ๐น๐๐ถ (DTU) โ Engineering ๐. ๐ฃ๐ฐ๐ถ๐ญ๐ข๐ณ๐ฅ๐ช๐ช to deliver gut-targeted therapies
Together, they uncover microbiome signatures to inform biomarker discovery & therapy development. Stay tuned! #CancerCachexia
#Microbiome #PhDResearch
๐งฌ Meet WP1 students!
Their focus? How the microbiome impacts cachexia across cancer types.
๐จโ๐ฌTongkun: cross-cancer multi-omics & ML models for diagnosis
๐ฉโ๐ฌMariem: epidemiology and microbiome of cachexia in colon cancer
๐ฉโ๐ฌMia: microbiome & muscle wasting links
๐ฉโ๐ฌRahma: cytokines & microbiome links
#MiCCrobioTAckle #CancerCachexia #GutMicrobiome #MicrobiomeResearch #PersonalizedMedicine #PhDResearch #ScienceForHealth
END
The gut microbiome regulates inflammation, metabolism, and appetite โ all disrupted in cancer cachexia.
Our work aims to improve patient outcomes and create personalized medicine solutions.
Join us in celebrating #WorldMicrobiomeDay and supporting microbiome science!
4/n
Our mission:
๐ Understand how the gut microbiome drives cancer cachexia
๐งฌ Find biomarkers for early diagnosis and prognosis
๐ก Develop new microbiome-based treatments
But why the gut microbiome?
3/n
Weโre a European research consortium training 12 PhD students across microbiology, computational biology, clinical research, and synthetic biology.
We are coordinated by @mbdlab.bsky.social at @leibniz-hki.de
2/n
๐ World Microbiome Day is almost here โ June 27!
Microbiomes are communities of bacteria, fungi, and viruses that impact our health in huge ways. At MiCCrobioTAckle, weโre researching how the gut microbiome affects cancer cachexia โ a serious condition affecting over 80% of cancer patients.
1/n
Here we are!
MiCCrobioTAckle is a @Horizoneu.bsky.social doctoral network coordinated by @Leibniz-HKI.de. Our goal is to advance research at the intersection between gut #microbiota and #cancer cachexia.
Follow us for exciting research!
#MSCA
#DoctoralNetworks
#HorizonEurope