Domain gain or loss in a fungal chitinase enables specialization towards antagonism or immune suppression - Nature Communications Gain or loss of a particular domain contributes to functional specialization of a conserved chitinase in beneficial root endophyte towards microbial antagonism or host immune suppression.

Really proud of this work led by Ruben Eichfeld! We show how a CBM domain gain/loss can rewire fungal chitinases, turning them from antifungal enzymes into immune-suppressing effectors that support plant symbiosis.

www.nature.com/articles/s41...

Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast Endosomes serve as crucial sorting centers that streamline the distribution of cell surface proteins. The early endosome receives traffic from both th…

Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast

The work from Alejandro Melero @ameleroc.bsky.social and Miguel Basante-Bedoya just out in Current Biology.

www.sciencedirect.com/science/arti...

@biology-unige.bsky.social

Cross-kingdom RNA interference promotes arbuscular mycorrhiza development - Nature Plants The authors provide evidence that symbiotic fungi forming widespread arbuscular mycorrhiza symbioses use cross-kingdom RNA interference to silence plant genes and promote their colonization of host ro...

www.nature.com/articles/s41...

RNA-specific local translation is patterned by condensates for multinucleate cell growth - Nature Cell Biology Geisterfer, Jalihal et al. show spatially distinct effects of Whi3 condensates on target translation in Ashbya syncytia. In vitro, translation is enriched at condensate–solute interfaces but repressed...

Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations.
www.nature.com/articles/s41...

The molecular basis of force selectivity by PIEZO2 Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function.
www.nature.com/articles/s41...

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

Comment une levure devient mycose

En élucidant le mécanisme qui rend le champignon microscopique Candida albicans capable de provoquer des mycoses, une équipe du CNRS ouvre la voie à de nouvelles pistes thérapeutiques.

#GGFungi2026 Call For Projects is now open for applications getgenome.net/callforproje...

We will be holding an information session today 3rd March at 14:00 CET (08:00 Eastern US; 18:00 PKT). To sign up please complete this short form - forms.office.com/e/DssYYkkY9Z

Poplar CLE peptides promoting ectomycorrhizal symbiosis identified through genome-wide analysis of responsive small secreted peptides Trees use CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides to promote ectomycorrhizal symbiosis, revealing an additional regulatory layer in tree–

🧵 New paper out in @PlantPhysiology! We asked: how do trees talk to their fungal partners during ectomycorrhizal symbiosis? Turns out, tiny secreted peptides play a big role. 1/

Read the full paper here 👇
academic.oup.com/plphys/advan...

CRAGE-RB-PI-seq reveals transcriptional dynamics of plant-associated bacteria during root colonization

▶️Pseudomonas simiae WCS417
▶️chassis-independent recombinase-assisted genome engineering-randomly-barcoded promoter-library insertion seq

-in @natcomms.nature.com

www.nature.com/articles/s41...

here is a comprehensive history of the use of agar in microbiology by corrado nai 👇
🙏 thx for pointing this out @microbingle.bsky.social
earlier, corrado told the story of fanny angelina hesse in STC.
#MicroSky

The mechanical properties of Arabidopsis thaliana roots adapt dynamically during development and to stress Brillouin microscopy reveals in vivo dynamics of mechanical properties during plant development and response to stress.

Our work now on its final version. We mapped the mechanical properties of roots at tissue and single cell levels using Brillouin microscopy and molecular rotors. Additional mutants and stress measurements from what we previously showed in the preprint are included.
www.science.org/doi/10.1126/...

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...

This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...

A 🆕 #Ichthyosporea story
Led by@margaridaaraujo.bsky.social, in Co. @gautamdey.bsky.social & @hiralshah.bsky.social+🔥team across @embl.org & @sciencesunige.bsky.social
We finally have a look at what #microtubules are doing during #cellularization in #Sphaeroforma
▶️ tinyurl.com/MTSARC
#ProtistsOnSky

📢 Happy to share our new preprint from @sophiemartinlab.bsky.social !
Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.

Fluidité intracellulaire et pouvoir infectieux du champignon Candida albicans Dans un article publié dans la revue Nature Microbiology, des scientifiques mettent en évidence un mécanisme jusque-là inconnu chez Candida albic

#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael

Farewell @adrigov.bsky.social! From joining our crew @cbgpmadrid.bsky.social as an undergraduate student until smashing it as a PhD and Postdoc in the #PollmannLab, it has been truly rewarding to see you grow into an amazing scientist. We'll miss you so much!!!! All the best at Uni. Nottingham 🫂

Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth - Nature Microbiology During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can tri...

#NewResearch

During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen.

#MicroSky 🦠

www.nature.com/articles/s41...

Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth - Nature Microbiology During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can tri...

Out now! Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth

@robertarkowitz.bsky.social

Read it here: rdcu.be/eT3CP

www.nature.com/articles/s41...

Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth Nature Microbiology - During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of...

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen
rdcu.be/eT1Su

Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity Treatment failure rates for fungal infections cannot be explained simply by increased rates of drug resistance. Antifungal drug tolerance, the ability of a susceptible isolate to grow in the presence ...

Excited to share our new study on antifungal drug tolerance in the human fungal pathogen Candida albicans.
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...

#Science #Microbiology #CellBiology #Fungi

Start independent research at the JIC with us 👇.

Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.

Please do get in touch by email if you'd like to know more 👍

Really happy to share our latest review article exploring the current knowledge on CW dynamics in the plant-microbe interactions!

Between Host and Invaders: The Subcellular Cell Wall Dynamics at the Plant–Pathogen Interface | Annual Reviews - www.annualreviews.org/content/jour...

✋ microPublication Biology has joined Bluesky.

PhD position avaiable at the CBGP with Clara Sánchez in Madrid, Spain. Share to anyone interested please! Open to international and national students.

PhD position avaiable at the CBGP with Clara Sánchez in Madrid, Spain. Share to anyone interested please! Open to international and national students.

#WIP #womeninSTEM trading cards #1000portraits

Cool microscopy following AMF formation and collapse on plant root for several days live imaging

Such a cool method visualization of spatial temporal patterns

See their paper on AMslide:
onlinelibrary.wiley.com/doi/full/10....

#KNVMmycology

The European Conference on Fungal Genetics ECFG17🧬 early registration deadline is approaching! Remember to register to the 3rd Symposium on the Basal Fungal Kingdom 🍄, too, for a lovely pre-meeting on the early-diverging fungi. More info @ ecfg17.org/ecfg17-satel...
#ECFG17
#mycology