Thanks to Julia Sanchez-Garrido for this nice news&views in Nature Immunology on our work! @juliasg.bsky.social @interactome.bsky.social @natmicrobiol.nature.com @natimmunol.nature.com

A big thank you to @intact-ebi.bsky.social for the great collaboration integrating our high-throughput binding affinity (Kd) measurements into their database! Check out the kind of data we can generate using the Holdup assay — and there’s much more to come!

Health Medinice Network covers our work how gut bacteria can control our immune responses by injecting their proteins into human cells. Implications for human health, especially #CrohnsDisease. #microbiome #health #autoimmune

www.nature.com/articles/s41...

healthmedicinet.com/gut-bacteria...

Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation Nature Microbiology, Published online: 26 January 2026; doi:10.1038/s41564-025-02241-yLarge-scale computational and in vitro analyses identify commensal type III secretion systems and substrates in the human gut microbiome that can interact with human proteins to modulate immune pathways.

Out Now! Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation #MicroSky

We acknowledge the support of @agencerecherche.bsky.social for the main grant, @univ-amu.fr via #amidex funding, @centuri-ls.bsky.social for PhD fellowships and @insermpacacorse.bsky.social @inserm.fr

Happy and proud as well to see the paper out in @natmicrobiol.nature.com! Thanks to Pascal @interactome.bsky.social and all collaborators for this fantastic work. A special thank to the people in our team at @tagc-u1090.bsky.social, @netbiotagc.bsky.social and Renaud at @afmblab.bsky.social

More Than Just Gut Cohabitants: How Gut Bacteria Control Immune Responses

More Than Just Gut Cohabitants: How Gut Bacteria Control Immune Responses

New research led by #HelmholtzMunich shows that common gut bacteria can actively shape our immune system by injecting proteins directly into human cells.

👉 t1p.de/g2b98
🔗 Original publication: t1p.de/v42xb

#Microbiome

Exonic enhancers are a widespread class of dual-function regulatory elements Exonic enhancers (EEs) occupy an under-appreciated niche in gene regulation. By integrating transcription factor binding, chromatin accessibility, and high-throughput enhancer-reporter assays, we demo...

Just out on bioRxiv!
Our latest study uncovers a widespread class of dual-function elements: Exonic Enhancers (EEs) — coding sequences that also act as cis-regulatory enhancers.
Check it out 👉 www.biorxiv.org/content/10.1...
#Genomics #GeneRegulation #Enhancers #ExonEnhancers

Happy to be back to #cshlnetworks meeting @cshlmeetings.bsky.social

Tomorrow, let’s #standupforscience #Science is for everyone!