Exons can regulate genes too!
Our new work shows that many coding exons are also enhancers, identified across species, and diseases. These exonic enhancers (EEs) can modulate gene expression and present regulatory variants.
#ExonEnhancers #BioRxiv #FunctionalGenomics

Exonic enhancers are a widespread class of dual-function regulatory elements Exonic enhancers (EEs) occupy an under-appreciated niche in gene regulation. By integrating transcription factor binding, chromatin accessibility, and high-throughput enhancer-reporter assays, we demo...

Just out on bioRxiv!
Our latest study uncovers a widespread class of dual-function elements: Exonic Enhancers (EEs) — coding sequences that also act as cis-regulatory enhancers.
Check it out 👉 www.biorxiv.org/content/10.1...
#Genomics #GeneRegulation #Enhancers #ExonEnhancers