Oh, I feel the pressure building up... 🧪

First post over here!
And it’s a link to our NDRG1 preprint!

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #9

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #8

6️⃣6️⃣ Dorothy June Sutor (1929-1990) 🇳🇿 #womeninSTEM New Zealand crystallographer. She was the first to establish the existence of C - H ⋯ O hydrogen bonds in crystals in 1962. Her work was wrongly criticised by Jerry Donohue.

www.chemistryworld.com/features/the...

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #7

Over 60 German and Austrian universities, the German Federal Court of Justice and multiple top German football clubs have announced that they will be withdrawing from Twitter (X), due to US oligarch Elon Musk's "discussion" (collaboration) with Germany's neo-Nazi party (AfD) Alice Weidl.

Yes this is exactly my strategy.

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #6

Oh yes this 3rd edition from 1988 still lives on...

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #5

Kukaan ei huomannut uutista: hallitus vaatii huomioimaan ”turvallisuuteen liittyvät näkökohdat” tutkimuksen rahoituksessa Luulisi, että esitys herättäisi uutisnälkäisessä toimittajassa kysymyksiä. Aletaanko Suomen Akatemiassa valvoa arvopohjaisen realismin noudattamista? kirjoittaa Anu Koivunen.

Näin tiede asetetaan poliittiseen kontrolliin.

"Akatemian tehtävien hoitaminen ei saa olla ristiriidassa Suomen kansallisen turvallisuuden, Suomen kansainvälisten velvoitteiden tai Suomen ulko- ja turvallisuuspolitiikan kanssa."
suomenkuvalehti.fi/mielipide/ku...

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #4

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky

#BookChallenge

#Books

Day #3

Had a little holiday break but here we go again...
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #2

Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order.
No explanations, no reviews, just covers.

#BookSky
#BookChallenge
#Books

Day #1

Black woman targeted by racist abuse in Finland over festival role Finnish PM apologises to Daniela Owusu after she received hate messages after becoming first Black woman to represent Saint Lucia

#finland still has a lot to learn #racism www.theguardian.com/world/2024/d...

Paratope mapping of tilvestamab, an anti-AXL function blocking antibody, using high-throughput bacterial expression of secreted scFv-ompY fusion proteins Targeting AXL with a highly selective antibody presents a promising approach for inhibiting AXL and potentially improving cancer treatment. An essential step in antibody optimisation is the mapping of...

One more preprint out - Santa can come now!
www.biorxiv.org/content/10.1... 🧪

The nanobodies were additionally expressed as intrabodies in both cultured oligodendrocytes and COS-7 cells. The nanobodies are freely available tools for structural biology as well as functional studies and molecular imaging.

Fluorescently labelled nanobodies were validated for staining of both teased nerve fibres and whole brain sections, as well as STED microscopy of nodes of Ranvier.

We developed and characterised a set of high-affinity nanobody binders against the myelin enzyme CNPase. A thorough biophysical characterisation was accompanied by high-resolution X-ray crystallography to identify the precise epitopes for each nanobody.

Hats off to funding sources and research infrastructures @unioulu.bsky.social @dfgpublic.bsky.social (again, cannot find most of you here but maybe soon).

Great collaborative effort with good friends including @opazo.bsky.social @myelincentric.bsky.social @sigurbjornm.bsky.social and many others (sorry if I did not find the rest you on this platform yet).

Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies The enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is abundant in non-compact myelin. While its in vitro catalytic activity is well understood, the in vivo function of CNPase remains un...

...and there we have it - the first paper for 2025 😀

onlinelibrary.wiley.com/doi/10.1111/...

Hehe, this is great! 7 years in the making, but only the starting point for the future - followup data are already being collected. 🧪

Mouse brain section stained with a nanobody anti-CNPase (cyan) and Dapi/nuclei in magenta

My 1st post in bsky is about our latest paper of 2024. Excellent collaboration with @petrikursula.bsky.social @myelincentric.bsky.social & Bradley Zuchero labs. We characterized a set of 🦙 #nanobodies binding myelin protein CNPase. It is online at @jneurochem.bsky.social: dx.doi.org/10.1111/jnc....

Thrilled to share our latest paper in PNAS! We enhanced SAXS with noncanonical amino acid labels to extract both RG and RE of IDPs, addressing key discrepancies in biophysical measurements. Big thanks to Lemke Lab for the amazing ASAXS-inspired T-shirt! www.pnas.org/doi/10.1073/...

Postdoctoral position in biophysical and structural characterization of auxin transport, Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University

Interested in structural biology, membrane proteins, biophysics and working onto understand hormone transport in plants?☘️🔬👩‍🔬🧪
We are recruiting a postdoc:
- Deadline 20. Dec 2024.
- 2(+2) year position.
- Details and application link: tinyurl.com/y7vnewen
- PM for questions
Please repost 💚

Latest from the lab now out as a preprint 😇🧪

Last lecture of 2024 is DONE! 🧪🎓🤠