📄 A recent study in #ACSNano by @heilemannlab.bsky.social shows that 🔬STED microscopy with DNA-fluorophore labels enables intensity-based molecular counting. Happy to see our #nanobodies 🦙 FluoTag®-X4 anti-GFP and sdAb anti-ALFA contribute to this work.
Read the paper here: doi.org/10.1021/acsn...

Broadly neutralizing #nanobodies target a defined structural pivot site on the #RSV fusion protein 🦠

➡️ doi.org/10.1038/s44321-026-00412-w

By Q. Wang, B. Shu, S. Chiu and colleagues atWuhan Institute of Virology & University of Science and Technology of China

👉 Result? #Nanobodies might just become the new gold standard for active targeting.
👉 And protein nanocapsules? A versatile, scalable platform for the future of cancer vaccines.
Carina, your work is impactful, and so much fun to follow.
All the best for what’s next! 🚀

✅ #Antibody conjugation works — but needs optimization
✅ Dual functionalization? Good in vitro.
✅ #Nanobodies? Equal targeting efficiency — but way easier & faster to produce.
#Nanomedicine #Immunotherapy #CancerResearch #Nanovaccine

Function | New Article Alert! 🚨#Nanobodies offer high stability, deep tissue access, and precise targeting. A new review highlights advances in their #engineering and their growing roles in imaging, therapy, and probing intracellular proteins. Read: https://ow.ly/FgLt50Yy94O

Minnesota researchers work to tame one of world’s deadliest viruses Marburg isn’t a household name like Ebola, but University of Minnesota researchers created a method for comparison and showed it 300 times more efficient at infecting human cells.

Coverage of Midwest AViDD's Co-Director Fang Li's
@natureportfolio.nature.com paper in the
@startribune.com! @fanglilabumn.bsky.social
#marburg #drugdiscovery #globalhealth #nanobodies www.startribune.com/u-of-m-resea...

New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...

Engineered nanobodies improved respiratory defenses in preclinical study In a multi-institutional study published today in Nature Nanotechnology, researchers from The University of Texas MD Anderson Cancer Center reported that engineered bispecific nanobodies successfully…

Engineered #nanobodies improved respiratory defenses ...

| #viruses | #infections | #influenza | #neuraminidase | Via eurekalert .org

While overexpression of AIM2 PYD-EGFP assembles filaments, co-expression of AIM2 nanobodies blocks filament formation and inflammasome asssembly

... identified #nanobodies that block AIM2 inflammasomes by interfering with AIM2 Pyrin filament oligomerization (sequences deposited in nanosaurus.org data base) ...

Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells - The EMBO Journal The innate immune system is known for its ability to recognize cytosolic DNA as evidence of infection, but detailed studies of this process have been mostly limited to mice and cell lines. To investig...

Ever wondered how you can specifically inhibit #AIM2 #inflammasomes? @y-m-tesfamariam.bsky.social generated inhibitory AIM2 #nanobodies to ‬dissect inflammasome responses to #poxvirus infections in human #PrimaryCells
@unibonn.bsky.social @immunosens.bsky.social link.springer.com/article/10.1...

Chameaux, lamas ou alpagas : quand le sang des camélidés vient au secours des humains Stables, de petite taille et faciles à associer, les anticorps des lamas, alpagas et autres dromadaires prennent une place croissante dans la panoplie médicale. Quatre médicaments ont déjà été autoris...

Du sang des camélidés à la médecine humaine.

De la maladie d’ #Alzheimer au #cancer : les #nanobodies, issus des anticorps de lamas et dromadaires, ouvrent de nouvelles pistes.

Plus petits, plus précis, déjà en essais cliniques. 🧬🦙

www.lemonde.fr/sciences/art...

We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT

📰New & Featured | #Nanobodies
Nanobodies—tiny, stable, highly specific single-domain antibodies—are transforming cancer diagnosis and therapy. From targeted #drugdelivery and advanced imaging to CAR-engineered #immune cells, they offer #precision beyond conventional antibodies.
ow.ly/4Y4H50XRPF5

Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice - PubMed Wet age-related macular degeneration (wAMD) is a leading cause of vision loss and is characterized by choroidal neovascularization (CNV). Current CNV management requires multiple treatments and lacks…

A first-in-class nanobody gene therapy enables sustained, intraocular inhibition of complement C3, significantly suppressing pathological neovascularization. #GeneTherapy #AMD #Complement #Nanobodies #Biotech #VisionScience #TranslationalMedicine buff.ly/JaWxxmB

✨ Blinking #nanobodies that work for single-molecule localization 🔬
Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!

Happy #MicroscopyMonday from our brilliant team recently at #CellBio25 Booth no. 416!

#scienceconference #sciencetravel #sciencecollaboration #labhelp #scienceconnections #nanobodies #livecellimaging #mitochondria #lysosome #microtubule #fixedcells #cellularimaging #microscopy

"Nanobodies can block HIV from entering cells by targeting the CD4 receptor, which the virus normally uses to infect immune cells."
🌍 #WorldAIDSDay2025
✍️ Supriya Mahajan, Associate Professor at Jacobs School at University at Buffalo
🔗 t.co/8YxvYZtTl6 #Nanobodies #HIV #AIDS #Health #News

And that's a wrap for #SFN2025! More exciting recap photos to come with friends new and old. 👋 See you in DC next year!

#scienceconference #sciencetravel #sciencecollaboration #labhelp #scienceconnections #nanobodies #sandiegoconventioncenter #societyforneuroscience

Unique Antibody from Camels and Alpacas Could Be Used to Treat Alzheimer's They're just one-tenth the size of conventional antibodies, and have not been found in any other mammals, say scientists.

Interesting! Tiny antibodies from camels and alpacas - called nanobodies - could revolutionize Alzheimer’s treatment! Their small size helps them cross the blood-brain barrier with fewer side effects. Human trials may be next. #Alzheimers #MedicalInnovation #Nanobodies
🔗

Destination: #SanDiego for #SFN2025! Come learn about our tools for #neuroscience like our new #MiniMab™ Single-Domain #Antibodies!

biotium.com/technology/m...

Collab with us! biotium.com/special-offe...

#scienceconference #sciencetravel #sciencecollaboration #scienceconnections #nanobodies

Unique Antibody from Camels and Alpacas Could Be Used to Treat Alzheimer’s An antibody-like compound known on land to be exclusively to be found in camelids like alpacas, lamas, and dromedaries, could be used to treat human brain disorders such as Alzheimer’s disease, according to a new study. The study’s focus were antibody-like proteins, aptly called nanobodies, whose small size allowed the scientists to treat neurological conditions […] The post Unique Antibody from Camels and Alpacas Could Be Used to Treat Alzheimer’s appeared first on Good News Network.

Unique Antibody from Camels and Alpacas Could Be Used to Treat Alzheimer’s: An antibody-like compound known on land to be exclusively to be found in camelids like alpacas, lamas, and dromedaries, could be used to treat… @goodnewsnetwork.org #Alzheimers #Nanobodies #Camelids #Research #Biotechnology

Are researchers leaving academia due to pressure to publish quickly? Is it possible to complete a high-quality, discovery-driven PhD in just 3 years? 🎧 Watch Episode #1 with Dr. Felipe Opazo to learn about #Nanobodies, #Microscopy, and the realities of #AcademicLife.

youtube.com/shorts/Jr8eY...

Darstellung eines Ausschnitts aus einem grünen Pflanzenblatt. Auf dem Blatt patrouillieren Antikörper-Moleküle. Das Bild steht sinnbildlich für das Konzept einer aufgerüsteten pflanzlichen Schädlingsabwehr durch ein adaptives Immunsystem via Nanobodies und Genetic Engineering. Rechts neben dem Bild steht die Überschrift "Pflanzenabwehr stärken" des im Post verlinkten Artikels, gefolgt von dessen Vorspann mit dem Text: "Forschende testen Strategien, wie sie via Nanobodys und genetischer Eingriffe Pflanzen mit einer Art adaptivem Immunsystem aufrüsten könnten."

#Pflanzen mit einem adaptiven #Immunsystem ausstatten – nur eine schöne Vision? Mit #Nanobodies und genetischen Eingriffen ist man diesem Ziel nun einen Schritt näher gekommen. Karin Hollricher erklärt auch, was dies für #Pflanzenschutz und -anbau bedeuten könnte: www.laborjournal.de/editorials/3...

Small but mighty: the versatility of nanobodies in modern medicine Nanotools in biomedicine open up novel applications in research, diagnostics, and clinical care. Here, nanobody technology has emerged as a powerful platform, offering advantages over conventional ant...

Summer is over and it was hot 🔥. We published three papers on our current research topics: a review on the medical application of nanobodies and two papers demonstrating new ways to specifically manipulate the activity of the protease Taspase1. Read more here 👉 doi.org/10.1039/D5NH00283D
#Nanobodies

Structural Insights into Antibody-based Inhibition of the Angiotensin Receptor The angiotensin II type I receptor (AT1R), a G protein-coupled receptor (GPCR) that regulates cardiac and renal function, is one of the most successful pha

Using a synthetic yeast display nanobody library, IPI cofounder Andrew Kruse & @harvardmed.bsky.social colleagues found #nanobodies that modulate AT1R function, distinct from small molecules.

A promising step for nanobody drugs & compelling use of #yeastdisplay ➡️ academic.oup.com/mam/article/...

Our first Tham Lab photo with Megan Outram and Grace Jones @biologyanu.bsky.social

🐸 We want to understand how chytrid fungus infects frogs using structural biology, nanobodies & genetic engineering

Excited to be branching out to fungal diseases

#chytrid #nanobodies #fungus #effector

Chao and colleagues show an image of glioblastoma (red) treated with CF17 oncolytic virus (green). Image credit: Jianfei Chao.

#MolecularTherapy Oncology's Sept 2025 issue covers new research on #Nanobodies, #OncolyticViruses, #BaseEditing, and #TherapeuticTargets in #Cancer. Check it out today: http://dlvr.it/TN8jsh
#ASGCT

Nanobodies: Tiny Antibodies with Big Potential in Medicine Llamas and camels produce nanobodies, which are tiny antibodies changing the way we treat diseases. Because of their small size and special structure, they can target illnesses like cancer and viral infections with great accuracy. These nanobodies open the door to a future of stronger and more precise treatments.

The next big medical breakthrough may not be a complex drug—it could be a tiny molecule from a llama. 🤔 This is not science fiction; it’s real and happening now. Explore the world of nanobodies and discover how they’re transforming medicine. #Biotech #Pharma #DrugDiscovery #Nanobodies

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#neuroscience #sciencecollaboration #nanobodies #labpartners #sciencehelp

🧱 Crystal structure shows binding on the opposite face to CDK, enabling ternary complex formation.
🧪 In cells, nanobodies act as pharmacological chaperones to restore p16 function!

#StructuralBiology #CellCycle #Nanobodies #CancerResearch #ProteinStability