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2D classes of a 58 kDa particle collected on a 100 kev Tundra electron microscope

2D classes of a 58 kDa particle collected on a 100 kev Tundra electron microscope

2D classes of the 58 kDa sample collected on the 100 keV Tundra TEM with a Falcon C detector at @nusbf.bsky.social @newcastleuni.bsky.social. Still much work to do to optimise the sample & data collection but its cool to see what a 100 keV TEM is capable of. #cryoEM @recon4imd.bsky.social

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Spin-labeling studies implicate a highly dynamic active state for transducin-bound phosphodiesterase-6 in vertebrate phototransduction www.biorxiv.org/content/10.64898/2026.04.01.715611v1 #cryoEM

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Cryo-ET reveals distinct Gag lattice architectures in virus-like particles and immature HIV-1 pubmed.ncbi.nlm.nih.gov/41928506/ #cryoEM

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Apical Localization of RNA Polymerases Modulate Transcription Dynamics and Supercoiling Domains Revealed by Cryo-ET pubmed.ncbi.nlm.nih.gov/41929223/ #cryoEM

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Using Cryogenic Electron Tomography (cryoET) to Determine Rubisco Polymerization Constants in alpha-Carboxysomes pubmed.ncbi.nlm.nih.gov/41929154/ #cryoEM

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The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing pubmed.ncbi.nlm.nih.gov/41929118/ #cryoEM

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MscM uses a novel gating mechanism for bacterial mechanosensitive channels pubmed.ncbi.nlm.nih.gov/41928924/ #cryoEM

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Variable Resolution Maps (VRM) in CCTBX and Phenix: Accounting For Local Resolution In cryoEM pubmed.ncbi.nlm.nih.gov/41928950/ #cryoEM

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Suppressing Transfer of Antibiotic Resistance by a Small RNA Virus pubmed.ncbi.nlm.nih.gov/41928967/ #cryoEM

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Structures and molecular mechanisms of RAD54B in modulating homologous recombination pubmed.ncbi.nlm.nih.gov/41929041/ #cryoEM

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Lipids are essential for potassium transport by KdpFABC from E. coli pubmed.ncbi.nlm.nih.gov/41929109/ #cryoEM

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Cryo-EM structures of photosystem I with alternative quinones reveals new insight into cofactor selectivity pubmed.ncbi.nlm.nih.gov/41929188/ #cryoEM

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Prefusion-specific glycoprotein B human antibodies protect against neonatal HSV-2 infection pubmed.ncbi.nlm.nih.gov/41929215/ #cryoEM

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Mechanisms of disassembly at the actin filament pointed and barbed ends pubmed.ncbi.nlm.nih.gov/41931606/ #cryoEM

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Structural insights into the mechanism underpinning iron piracy in pathogenic Neisseria pubmed.ncbi.nlm.nih.gov/41931607/ #cryoEM

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Cryo-EM structures of human P2X2/3 heteromer channel reveal the structural basis of ligand selectivity pubmed.ncbi.nlm.nih.gov/41931608/ #cryoEM

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Chaperonin TRiC bridges radial spokes for folding locally translated proteins to sustain mammalian sperm flagellar motility pubmed.ncbi.nlm.nih.gov/41932310/ #cryoEM

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Mechanosensory channels mediate ER Ca2+ transients to trigger assembly of autophagosome initiation sites for degradation of ER subdomains pubmed.ncbi.nlm.nih.gov/41932312/ #cryoEM

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Preview
8th Instruct | FRISBI | PSB Grenoble Cryo-EM Course on Sample Preparation <p><img src="https://instruct-eric.org/upload/nOyS9ZN04jpBMHRN82vhcPbOmNcSlgQa.png" /></p> <p>We are pleased to announce the eighth hands-on practical course on sample preparation for single-particle…

Instruct | FRISBI | @psb-grenoble.bsky.social Cryo-EM Course on Sample Preparation
📅 19 – 22 May 2026
📍 European Photon and Neutron Campus, Grenoble, France
📝 Registration Open| Deadline: 12 April 2026
🔗 instruct-eric.org/events/8th-i...

#CryoEM #Training

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A fragment of 12S seed storage protein of Arabidopsis forms twisted cross beta-sheet rich amyloid fibrils pubmed.ncbi.nlm.nih.gov/41932473/ #cryoEM

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The Mycobacterium abscessus cytochrome bcc:aa3 oxidase structure paves the way for an agent targeting subunit QcrB pubmed.ncbi.nlm.nih.gov/41932870/ #cryoEM

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Dynamic monomer-dimer transition in ligand-induced apelin receptor activation pubmed.ncbi.nlm.nih.gov/41932888/ #cryoEM

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Structural insights into C-terminus-mediated RNA target cleavage by a mesophilic prokaryotic argonaute pubmed.ncbi.nlm.nih.gov/41932907/ #cryoEM

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The transmembrane domain regulates the kinetics of the SARS-CoV-2 spike conformational transition www.biorxiv.org/content/10.64898/2026.04.03.716256v1 #cryoEM

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Cryo-EM Structure of Human ATAD2B Reveals a Hexameric Organization Contributes to ATPase Activity and Substrate Coordination www.biorxiv.org/content/10.64898/2026.04.02.716110v1 #cryoEM

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Predictive Screening of Ta4C3 MXene as an Inhalable Nanotherapeutic Based on an Advanced 3D Air-Liquid Interface Lung Model pubmed.ncbi.nlm.nih.gov/41925143/ #cryoEM

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Crosslinker nanocarrier-based intratumoral delivery for protein complex mapping in mitochondria of live tumor-bearing mice pubmed.ncbi.nlm.nih.gov/41924577/ #cryoEM

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Post image

At the Bay Area #CryoEM meeting with @matt-braga.bsky.social killin’ it with a presentation on a screening method for small protein SPA! (Unfortunately, there was a poorly positioned monitor in the way)

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Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism pubmed.ncbi.nlm.nih.gov/41926538/ #cryoEM

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Bacterial collagenase harnesses collagen geometry for processive cleavage pubmed.ncbi.nlm.nih.gov/41927550/ #cryoEM

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