Impaired #vitaminD signaling reveals #neutrophils as key drivers of #ProstateCancer dissemination

🗞️ doi.org/10.1038/s44321-026-00417-5
by K. Len-Tayon, @gilleslaverny.bsky.social & colleagues @igbmc.bsky.social

New comment by M. Smits, M. van Daal, S. Fuchs, K. Jongsma & colleagues: "Fair priority setting in #GeneEditing research: the accountability for reasonableness framework"

🗞️ doi.org/10.1038/s44321-026-00420-w

Broadly neutralizing #nanobodies target a defined structural pivot site on the #RSV fusion protein 🦠

➡️ doi.org/10.1038/s44321-026-00412-w

By Q. Wang, B. Shu, S. Chiu and colleagues atWuhan Institute of Virology & University of Science and Technology of China

❗Read the new Review on anti-tubercular target validation by Valerie Mizrahi at University of Cape Town, Dirk Schnappinger @weillcornell.bsky.social & colleagues ➡️ doi.org/10.1038/s44321-026-00415-7

#tuberculosis

#Hyperglycemia impairs #CognitiveFunction by inducing mitochondrial damage through #lactylation of LRPPRC at K223

👉 doi.org/10.1038/s44321-026-00422-8

by J. Xu, T. Zheng & colleagues at Guilin Medical University

📣The anti-obesogenic metabolite, Lac-Phe, is elevated by #metformin treatment in #ProstateCancer patients

By M. Bilusic, D. Lombard, P. Rai & colleagues at University of Miami Miller School of Medicine

🗞️ doi.org/10.1038/s44321-026-00408-6

If journals shape scientific #careers, shouldn’t we evaluate their quality more rigorously? 🧪

A Science & Society article explores why it may be time to rethink how we assess the quality and impact of journals: link.springer.com/article/10.1038/s44319-0...

#LifeSciences #publishing

Online today! #Tomatidine is a #senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice

By D. Costa, @dianajurk.bsky.social & colleagues @mayoclinic.org

🗞️ doi.org/10.1038/s44321-026-00400-0

JAK1/2 inhibitor #ruxolitinib reduces aggregates in cardiac #proteinopathy

By E. Alizoti, S. R. Singh & colleagues @dzhk.de

🗞️ doi.org/10.1038/s44321-026-00411-x

The lipid transfer protein #STARD7 controls intestinal tumor development in a context-dependent manner 👉 doi.org/10.1038/s44321-026-00409-5

by K. Shostak, A. Chariot & colleagues at University of Liege & WEL Research Institute

#TenascinC orchestrates #radiotherapy -induced head and neck tumor regression #HNSCC by T. Loustau, G. Orend & colleagues @unistra.fr @inserm.fr

🗞️ doi.org/10.1038/s44321-026-00406-8

Bcl-xL blockade targets #neutrophils and synergizes with #chemotherapy in #LungSquamousCellCarcinoma

➡️ doi.org/10.1038/s44321-026-00401-z

by A. Mayet, E. Meylan & colleagues @ulbruxelles.bsky.social & University of Lausanne

CDK12/CDK13 inhibition disrupts transcriptional elongation and #ReplicationFork progression in #glioblastoma

By S. Lier, M. Lerdrup, D. Pandey & colleagues at University of Copenhagen & University of Oslo

🗞️ doi.org/10.1038/s44321-026-00393-w

A skin colonizer disrupts inflammatory and humoral immune defenses in hidradenitis suppurativa - EMBO Molecular Medicine Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with a polybacterial dysbiosis devoid of a known pathogen. Here, we report that HS patients mount IgA and IgG responses ...

New study by L Guenin-Macé, O Join-Lambert, @demangelab.bsky.social & al. @pasteur.fr @univrouen.bsky.social ➡️ P. uenonis colonizes #HidradenitisSuppurativa skin & crosses the epidermis to invade keratinocytes

#Infection #ChronicInflammation #Autoimmunity

🗞️ doi.org/10.1038/s44321-026-00407-7

#IGFBP3 repression driven by inflammation links #AirPollution to placental and #DevelopmentalDefects by S. Singh, R. Dhar, S. Karmakar & colleagues at All India Institute of Medical Sciences

🗞️ doi.org/10.1038/s44321-026-00403-x

Blocking microglial reactivity via #purinergic receptors prevents subacute #cognitivedeficits after TIA ➡️ doi.org/10.1038/s44321-026-00397-6

By G. Llovera, @arthurliesz.bsky.social & colleagues @synergy-munich.bsky.social

Read related N&V by Kibin Shi & al 🗞️ doi.org/10.1038/s44321-026-00404-w

Online today! Betrixaban activates #cGAS and ERVs to promote dual nucleic-sensing #antiviral #immunity

By Y. Zhao, X. Wang, X. Guo, F. You & colleagues at Peking University

➡️ doi.org/10.1038/s44321-025-00356-7

Tumor Metabolism: New Frontiers in Diet, Microbiome and Beyond | Keystone Symposia Join us at the Keystone Symposia on Tumor Metabolism: New Frontiers in Diet, Microbiome and Beyond, June 2026, in Killarney, with field leaders!

Deadlines are approaching for @keystoneSymposia.bsky.social #TumorMetabolism : Diet, #Microbiome & Beyond, this June in Killarney. @embomolmed.org editor Lise Roth is looking forward to the meeting. See abstract and discount reg dates: hubs.la/Q03TCsnZ0 #KSTumorMetab26

Our March issue is now online! 🗞️ link.springer.com/journal/4432...

The cover highlights the article by S. Gan, C. Zhang, W. Yang, Y. Li, H. Huang and colleagues on #HNRNPR mutations and #FertilizationFailure 👉 doi.org/10.1038/s44321-026-00374-z

Metabolically reprogrammed #eosinophils impair T cell immunity and cause chronic #SkinInfection

By D. Barinberg, C. Bogdan, U. Schleicher & colleagues @fau.de

🗞️ doi.org/10.1038/s44321-026-00392-x

TDP-43 pathology triggers #neuroinflammation and #CognitiveImpairment by inducing microglial necroptosis, by S. Guo, C. Fu, Y. Yin, W. Cheng & colleagues at Xinhua Hospital, Shanghai

🗞️ doi.org/10.1038/s44321-026-00394-9

Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations | Keystone Symposia Join us at the Keystone Symposia on Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations, March 2026, in Québec, with field leaders!

Our editor Lise Roth will be attending #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec with @keystoneSymposia.bsky.social

Reach out to talk about your research!

keysym.us/KSCancerImmune26 #KSCancerImmune26

IFN-gene signatures in #Bcells following #influenza A and B virus infection and influenza #vaccination 👉 doi.org/10.1038/s44321-026-00395-8

By W. Zhang, @katherinekedz.bsky.social , T. Nguyen & colleagues @unimelb.edu.au @thedohertyinst.bsky.social

Online now! Cell-free DNA #methylome and #fragmentome analysis for relapse monitoring of #EwingSarcoma

By S. Richardson, M. McCabe, @florentmouliere.bsky.social & colleagues @cancerresearchuk.org @manchester.ac.uk

➡️ doi.org/10.1038/s44321-026-00396-7

Thanks so much Arica! It has been a fruitful week of science at #EMBLCardioBiology. I am really honored to receive the prize sponsored by @embomolmed.org. It means a lot to me.

I would also like to thank the scientists I met there. The discussions were inspiring! #zebrafishrocks #cardiobiologyrocks

Sign up by 6 March for the EMBO Lab Leadership #training "How to write a scientific paper" delivered by EMBO Press editors at EMBO | EMBL Symposium "#AI and #biology." 🧪 www.embl.org/about/info/course-and-co... #EESAIBio #EMBOevents

Structure-guided design of a PfCyRPA-based #vaccine against blood-stage #malaria

➡️ doi.org/10.1038/s44321-026-00376-x

By N. Alam, @parasitematt.bsky.social and colleagues @ox.ac.uk @kavlioxford.bsky.social

Read this @emboreports.org paper here=> link.springer.com/article/10.1...

KCNA2 variants cause dilated #cardiomyopathy, #obesity and #SleepApnea through RAC-ERK pathway

By P. Chimata, P. Dhandapany & colleagues at Institute for Stem Cell Science and Regenerative Medicine

👉 doi.org/10.1038/s44321-026-00391-y

#CITED2 is a druggable #EpigeneticSwitch coupling neuronal maturation to regenerative decline

By F. Müller, S. Di Giovanni & colleagues @imperialcollegeldn.bsky.social

🗞️ doi.org/10.1038/s44321-026-00385-w