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Posts by Biological Sciences

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1 of 2. Last night @sotonbiosciences.bsky.social students set mammal traps with @fieldstudiesc.bsky.social Nettlecombe Court staff who are licensed and trained to do this. We used Longworth traps with lots of straw and plenty of food... Mice and a vole. We opened traps in a bag, weighed and released

1 day ago 3 1 1 0
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Day 2 of @unisouthampton.bsky.social @sotonbiosciences.bsky.social @fieldstudiesc.bsky.social trip, we have been to Embercoombe Exmoor for a freshwater exercises. We explored the riffles and pools along streams, survived a stampede of ponies was exciting, and found invertebrate nymphs and larvae

1 day ago 3 1 1 0
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University of Southampton joins ELIXIR-UK as it newest member The University of Southampton has joined ELIXIR-UK, bringing expertise in computational biology, bioinformatics, clinical data, and data stewardship.

The University of Southampton has joined ELIXIR-UK 🎉 From open-access glycan databases to data stewardship, Southampton brings a wealth of expertise to the network.

Read more: elixiruknode.org/news/2026/un...

@elisafadda.bsky.social @glycoshape.org #openscience #bioinformatics #datastewardship

2 days ago 7 4 1 1
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2 days ago 1 1 0 0
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A great first day @fieldstudiesc.bsky.social Nettlecombe. We went to Helwell Bay and did a beach transect. The @sotonbiosciences.bsky.social students enjoyed the weather and doing some science. The rock formation showed Triassic red mudstones and grey Jurassic rocks.

2 days ago 1 1 1 0
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And we're off! @sotonbiosciences.bsky.social field trip to @fieldstudiesc.bsky.social Nettlecombe Court. Rocky shore, grassland and fresh water studies await!
@unisouthampton.bsky.social #fieldwork #ecology
(There are more students on the second coach they just hid from the camera).

3 days ago 7 1 1 0
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Proud of Jiaoqi Cheng who has successfully passed her PhD viva 🎉 🎓Many thanks to her examiners, Susana Godinho @susanagodinho.bsky.social and Charlie Birts @sotonbiosciences.bsky.social #theeliaslab

1 week ago 6 1 0 0

Extremely happy to receive an Academy of Medical Sciences Springboard Award for my research program on phage-based approaches to tackle antibiotic-resistant and biofilm-associated infections 🧫 🔬 🧪
A research assistant position will be advertised soon - watch this space!
@sotonbiosciences.bsky.social

1 week ago 6 1 2 0
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Our giant paper on a small crocodyliform is out! We have a comprehensive atlas of the osteology and neuroanatomy of Koumpiodontosuchus. Amazing work from @christijanibarker.bsky.social @tetzoo.bsky.social Mark Young Katy Rankin, et al
@sotonbiosciences.bsky.social
academic.oup.com/zoolinnean/a...

1 week ago 43 7 1 2
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Our new paper on a tiny Wealden 🐊 is now out, with @tetzoo.bsky.social, @neilgostling.bsky.social and co. As a critical taxon close to the origins of the living croc lineage, we used microCT to build a comprehensive morpholgical atlas to reassess its evolutionary relationships. tinyurl.com/4t592crr

1 week ago 40 16 0 0
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An unassuming yellow wildflower, steeped in folklore for its healing powers, has been proven to have genuine medicinal qualities.

Read more 👉 https://tr.ee/yO1PWB

4 weeks ago 3 2 0 0
New Awards 2026 | Human Frontier Science Program

Happy to announce that we received the HFSP to study the evolution of TRP channels! bit.ly/4uGmMQ3
This project is a collaboration between Luis Bezares from the @biodev-vlfr.bsky.social LBDV in Viellefranch and the University of Southampton. @unisouthampton.bsky.social

4 weeks ago 18 7 6 0

Fantastic job from these amazing Biosciences ECRs 👇🏼 inspiring & wowing crowds #sotsef2026 on Sat 👩🏼‍🔬 With 5000 visitors @unisouthampton.bsky.social campus they didn't stop all day 👏🏼👏🏼 😅 🥳! #bsw26 Now back to finishing experiments & writing the dissertations. Best of luck! ✍🏼🍀@uosengagement.bsky.social

1 month ago 2 1 0 0

Could weight loss jabs help treat breast cancer?

Dr Charlie Birts talks to ITV Meridian about new research exploring whether weight loss jabs could help reduce the risk of getting breast cancer and increase the effectiveness of treatment.

Watch here:
www.itv.com/watch/news/c...

1 month ago 1 0 0 0

@uosengagement.bsky.social @uosmedia.bsky.social

1 month ago 0 0 0 0
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Our masters students have been very busy preparing for their Outreach festival & now all set for #sotsef2026 🤩Come say hello👋🏼 B100 rm 5013 Saturday! Find out about their research projects studying Crohn's disease 🧫, gut microbiome 🦠, immune cell sorting, brain health, zebra poo 🦓 & more! #bsw

1 month ago 8 3 2 1
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@engineering-soton.bsky.social @mjtplantbiology.bsky.social @drmicrowill.bsky.social @sotonbiosciences.bsky.social

1 month ago 3 2 0 1
Artist’s impression of two large spinosaurus dinosaurs standing in shallow water during a smoky prehistoric wildfire scene, with flying reptiles overhead and one dinosaur roaring while the other stands nearby. Credit: Anthony Hutchings.

Artist’s impression of two large spinosaurus dinosaurs standing in shallow water during a smoky prehistoric wildfire scene, with flying reptiles overhead and one dinosaur roaring while the other stands nearby. Credit: Anthony Hutchings.

wearing round glasses, a green tweed jacket, white shirt, and patterned tie, smiling while seated in an office or lab workspace. Behind him are shelves with files, a computer monitor, and a fossil-like sculpture

wearing round glasses, a green tweed jacket, white shirt, and patterned tie, smiling while seated in an office or lab workspace. Behind him are shelves with files, a computer monitor, and a fossil-like sculpture

Proud to celebrate our dinosaur expert Dr Neil Gostling and former student Thomas Land for their parts in the new Spielberg documentary The Dinosaurs on Netflix 🦕

Dr Gostling researched Spinosaurus habits, and Thomas was a science researcher.

Find out more: www.southampton.ac.uk/news/2026/03...

1 month ago 25 12 0 1
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And check out the #FirstPerson interview with Miguel Ramirez-Moreno, where he talks about what sparked his interest in research, breaks down his work in simple language and discusses his plans for future studies.

Read: doi.org/10.1242/dmm....

1 month ago 3 1 0 0
Images showing how expressing human Tau in the Drosophila wing reduces the size of the posterior compartment. Panels include: a schematic of larval and adult wings highlighting the posterior region; fluorescent wing discs expressing control mCD8::Cherry or mCherry‑tagged human Tau with E‑cadherin staining; quantification plots comparing posterior/anterior size ratios; and adult wings with the posterior compartment outlined, demonstrating that Tau isoforms 0N4R and 2N4R significantly shrink this region.

Images showing how expressing human Tau in the Drosophila wing reduces the size of the posterior compartment. Panels include: a schematic of larval and adult wings highlighting the posterior region; fluorescent wing discs expressing control mCD8::Cherry or mCherry‑tagged human Tau with E‑cadherin staining; quantification plots comparing posterior/anterior size ratios; and adult wings with the posterior compartment outlined, demonstrating that Tau isoforms 0N4R and 2N4R significantly shrink this region.

@miguelrmphd.bsky.social, Douglas Watt Allan, Amritpal Mudher & co model Tau-induced neurotoxicity in the #Drosophila wing, enabling a rapid, genetically tractable in vivo system for #tauopathies studies.

Read doi.org/10.1242/dmm....

@sotonbiosciences.bsky.social @unisouthampton.bsky.social

1 month ago 4 4 1 0
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Here's your sign! Why you need to attend the Science and Engineering Day 2026?

📅 Saturday 14 March 2026
⏰ 10:30 – 16:30
📍Highfield Campus and Boldrewood Innovation Campus
👉 Tickets: www.sotsef.co.uk/SED 🔍

#SOTSEF #WeAreUoS #BSW26 @uosmedia.bsky.social

1 month ago 2 6 0 0

In our latest work, we characterise the Tmn defence system. We reveal plasmolysis as a new way to block phage infection, dramatically reducing secondary infections.

1 month ago 27 19 1 1
A bat flying through the air

A bat flying through the air

From caves to crops: Dr Veronica Zamora-Gutierrez is leading new research funded by @leverhulme.ac.uk to explore the hidden value of bat guano and how protecting bats also matters for food security.

Read more in the Leverhulme Trust newsletter: www.flipsnack.com/leverhulmetr...

1 month ago 12 6 0 1
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Hiring two postdocs, 3-years each, at @unisouthampton.bsky.social. We're investigating bat guano in Mexico

One postdoc in my group - plant/soil micro/microbiome: tinyurl.com/2zu8nrmv

One postdoc in bat ecology + ecoservices: tinyurl.com/27attrsc

Deadline March 30

@sotonbiosciences.bsky.social

1 month ago 1 2 0 0
A promotional poster for the Southampton Science and Engineering Festival and the University of Southampton. The event is titled “The science of Jurassic Park: Talk + Film screening + Q&A” presented by Dr Neil Gostling. It takes place at Avenue Campus on Tuesday 10th March from 18:00 to 22:00. The poster includes a circular photo of a person wearing a vest and lanyard, standing beside what appears to be a model or sculpture of a dinosaur head. At the bottom, there is a dark blue banner stating “Book your FREE tickets” with a link: bit.ly/SOTSEF26JurassicNight. The hashtag #SOTSEF appears in the lower right corner.

A promotional poster for the Southampton Science and Engineering Festival and the University of Southampton. The event is titled “The science of Jurassic Park: Talk + Film screening + Q&A” presented by Dr Neil Gostling. It takes place at Avenue Campus on Tuesday 10th March from 18:00 to 22:00. The poster includes a circular photo of a person wearing a vest and lanyard, standing beside what appears to be a model or sculpture of a dinosaur head. At the bottom, there is a dark blue banner stating “Book your FREE tickets” with a link: bit.ly/SOTSEF26JurassicNight. The hashtag #SOTSEF appears in the lower right corner.

Get ready for a roar-some evening! Join Dr Neil Gostling for the screening of Jurassic Park, followed by a discussion around the science of the film, and the science in reality!

Ticket: bit.ly/SOTSEF26Jura...
#SOTSEF #WeAreUoS #BSW26 @sotonbiosciences.bsky.social @unisouthampton.bsky.social

2 months ago 2 2 0 0

Join us 4 #SOTSEF👇😀! with Masters students &
Secret Life of Organoids, Inner working of Cells,
Health Innovations 🏃‍♂️ @clarkinbonebiol.bsky.social @fnobrega.bsky.social 🦠 @nelani.bsky.social Microbes, Mood & Murals 🎨 @jt8teeling.bsky.social & Sci of Jurassic Park 🦖! @neilgostling.bsky.social #BSW26

2 months ago 6 5 0 0
A brain made up of multiple coloured dots on a black background

A brain made up of multiple coloured dots on a black background

Professor Amritpal Mudher is part of a team of scientists who have developed a drug to prevent the build-up of Tau protein in the brain, which could pave the way for more effective treatments for neurogenerative diseases like Alzheimer's.

Find out more: www.southampton.ac.uk/research/hig...

2 months ago 2 0 0 0
A methylome-derived m6-dAMP trigger assembles a PUA-Cal-HAD immune filament that depletes dNTPs to abort phage infection Bacteria must distinguish phage attack from normal homeostatic processes, yet the danger signals that trigger many defence systems remain unknown. Here, we show that a PUA-Calcineurin-CE-HAD module from Escherichia coli ECOR28 confers broad anti-phage protection by binding Dam-methylated deoxyadenosine monophosphate (m6-dAMP) generated during phage-induced chromosome degradation. Ligand binding converts a preassembled PUA-Calcineurin-CE hexamer loaded with six HAD phosphatases into a polymerising filament. The filament acts as a high-flux dNTP sink through a two-enzyme cascade: HAD first dephosphorylates dATP to dADP, and Calcineurin-CE then converts dADP to dAMP. dNTP collapse halts phage replication and enforces abortive infection. Multiple mobile-element DNA mimic proteins block filament assembly, revealing a direct phage counter-defence. More broadly, our findings extend a conserved, cross-kingdom paradigm of immune filament assembly to nucleotide-depletion antiviral defence and suggest modified-nucleotide sensing by related PUA-Calcineurin-CE modules as a widespread, underappreciated bacterial strategy. ### Competing Interest Statement The authors have declared no competing interest. NIHR Southampton Biomedical Research Centre, https://ror.org/01qqpzg67, Postdoctoral Bridging Fellowship F.L.N. is supported by a Wessex Health Partners (WHP) and National Institute for Health and Care Research Wessex Experimental Medicine Network (NIHR WEMN), Seed fund National Institutes of Health, GM145888, U24 GM129539) Maloris Foundation Memorial Sloan Kettering Cancer Center, P30-CA008748 Simons Foundation, SF349247 New York State Assembly

Preprint out: We characterise PUA-Cal-HAD, a widespread bacterial antiphage defence family. An infection cue switches a preassembled complex into an immune filament that drains dNTPs via a coupled two-enzyme cascade, and phage DNA mimics can block filament assembly (anti-polymerisation).

3 months ago 34 19 1 0

Thoroughly enjoying our @sotonbiosciences.bsky.social Away Day. Lots of good discussion about the future of teaching, KEE and how we're going to keep delivering world class research. Great turnout as well, plus lunch was yum too!

3 months ago 2 1 0 0
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Next-generation phage therapeutics for combating antibiotic-resistant infections at University of Southampton on FindAPhD.com PhD Project - Next-generation phage therapeutics for combating antibiotic-resistant infections at University of Southampton, listed on FindAPhD.com

PhD studentship available: Join the phage frontline against AMR! 🧫 🔬
Funded by Wessex Medical Research × Rosetrees Trust.
With @fnobrega.bsky.social, Prof Saul Faust (NIHR Southampton), Dr Liz Sheridan (NHS Dorset).
Info & Apply → www.findaphd.com/phds/project...
Email me for informal enquiries

3 months ago 9 5 0 0
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