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Posts by Emily McDonald

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Quantifying Potential Immortal Time Bias in Observational Studies in Acute Severe Infection Immortal time bias is a spurious or exaggerated protective association that commonly arises in naive analyses of observational data. It occurs when people receive the intervention because they survive...

Glad to see @dremilymcd.bsky.social raising awareness of Immortal Time Bias at #ESCMIDGlobal2026

It's important and REALLY COMMON!

Here is a link to our paper on ITB in observational studies estimating the survival 'benefits' of IVIG in streptococcal toxic shock syndrome

3 days ago 1 1 0 0
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๐Ÿ“ข The International Conference on Deprescribing (ICOD) 2026 is fast approaching!

Happening in Montreal Canada ๐Ÿ‡จ๐Ÿ‡ฆ from April 27-29, 2026, @deprescribing.bsky.social is excited to connect with you there!

For registered attendees, be sure to review the Conference Agenda located here:
buff.ly/s6EEP3j

6 days ago 4 2 0 0
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๐Ÿ“ฃ Spotlight on a plenary at International Conference on Deprescribing (ICOD) 2026!

Marking 10 years of CADeN, past and present leaders will reflect on its evolution, from deprescribing to broader appropriate use of medications, and CADeN's future priorities.

๐Ÿ”— www.deprescribingnetwork.ca/icod2026

3 weeks ago 1 1 1 0
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๐Ÿ‡จ๐Ÿ‡ฆ New national guidelines developed by CADeN to screen for potentially inappropriate prescriptions.

Guidelines recommend:
1. regular med reviews for older adults taking any number of meds, and
2. government funding to encourage & support this process in primary care.

๐Ÿ”— www.cfp.ca/content/72/3...

1 month ago 4 3 1 0

Would be happy to host a communicable episode on WikiGuidelines โ˜บ๏ธ๐Ÿ˜Š

1 month ago 2 0 0 0

@caden-recad.bsky.social congratulations team! This grant will support our new tool to address safety of sedative hypnotics to better meet the needs of Indigenous peoples in Canada

1 month ago 2 1 0 0

Exactly

1 month ago 1 0 0 0

Dr Spellberg commented on X is spot on here
"Agree. The K-M curve is striking and makes me wonder sincerely, would fidaxo actually have been superior in its original RCT if the follow up had been longer. Are we spending all that money for a short term benefit that evaporates over time?"

1 month ago 8 1 2 0
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Congrats to @drtoddlee.bsky.social & @dremilymcd.bsky.social on conducting this and getting it out there for us. Look forward to wading through the details soon!

1 month ago 8 1 0 0
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Initial Vancomycin Taper for the Prevention of Recurrent C difficile Infection This randomized clinical trial tested whether a 4-week pulse and taper vancomycin regimen was superior to a 2-week pulse regimen for preventing recurrence among patients with a first episode or first ...

๐Ÿ”ฅJust published ๐Ÿ”ฅ
TAPER-V RCT
In this RCT of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to a standard 2-week pulse regimen in patients a first episode or first recurrence of CDI
Vanco for 10d is obsolete! #IDSky #EMIMCC
jamanetwork.com/journals/jam...

1 month ago 40 10 7 9
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๐Ÿ’ฐ Researchers at The Institute have secured $15.4M through the CIHR Fall 2025 Project Grants Competition to lead 14 new projects advancing human health. @cusm-muhc.bsky.social @healthsciences.mcgill.ca @sante.quebec
๐Ÿ”— rimuhc.ca/en/-/fall-20...

2 months ago 2 1 1 0
Screenshot of Emily McDonald, Virginie Lemiale, Josh Nosanchuk, Nav Narayanan, and Elie Azoulay discussing the Lemiale trial on steroids for PCP in non-HIV patients and how to interpret its results.

Screenshot of Emily McDonald, Virginie Lemiale, Josh Nosanchuk, Nav Narayanan, and Elie Azoulay discussing the Lemiale trial on steroids for PCP in non-HIV patients and how to interpret its results.

CMI Comms will do better teasing next #Communicable episode, but can't help but put this out there now (just listened):
V Lemiale & E Azoulay on their #steroids for #PCP RCT, then @dremilymcd.bsky.social on her Bayesian re-analysis of their data. Such a cool discussion. Hosted by Nav & Josh.
#IDSky

2 months ago 13 1 2 0
Infographic from JAMA. It presents a study about electronic health record interventions for deprescribing medications to older adults. Population: 799 women, 347 men, mean age 73.6 years. Findings: Precommitment intervention 36.8%, Boostering intervention 34.3%, Usual care 26.8%.

Infographic from JAMA. It presents a study about electronic health record interventions for deprescribing medications to older adults. Population: 799 women, 347 men, mean age 73.6 years. Findings: Precommitment intervention 36.8%, Boostering intervention 34.3%, Usual care 26.8%.

Among older adults receiving care in an academic health system, behavioral scienceโ€“informed electronic health record interventions increased deprescribing or tapering of potentially inappropriate medications compared with usual care.

ja.ma/4a4IGCT

2 months ago 8 5 0 1

This was a fun episode to record! Hope everyone enjoys :)

2 months ago 3 0 0 0

Pretty cool that Robin Patel picks Ouli Xie's @lancetmicrobe.bsky.social paper on SDSE and S pyogenes as one of her top 3 clinical microbiology papers for 2025! As expected, Robin does a great job explaining the paper.

www.thelancet.com/journals/lan...

@onisillos.bsky.social

3 months ago 15 7 2 0
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Preview
The beating heart of a broken machine

๐Ÿ“ฃ A peer reviewer used #AI to create a fake review with 6 self-citation prompts. But is s/he the only perpetrator in our system? In the year's first editorial, Angela Huttner explores the depths of the academic-industrial complex.

#IDSky #clinmicro #peerreview

https://ow.ly/juoW50Y05t6

3 months ago 14 10 2 1

Gotta love that graphical abstract lol

2 months ago 1 0 0 0
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Contextualizing the use of corticosteroids in severe Pneumocystis jirovecii pneumonia through a Bayesian lens A recent multicenter randomized clinical trial (RCT) of steroids for severe Pneumocystis jirovecii pneumonia (PCP) in patients without HIV failed to demonstrate a significant benefit in its primary ou...

๐Ÿ“ฃ Are steroids likely to reduce mortality in non-HIV patients with severe PCP? @drtoddlee.bsky.social, @dremilymcd.bsky.social et al. reexamine the Lemiale RCT with a Bayesian lens to find out.

#IDSky #clinmicro #PCP #immunosky #medsky

www.cmi-comms.org/article/S295...

3 months ago 5 3 1 0
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Get ready for the next International Conference on Deprescribing! #ICOD2026 in Montreal, Canada April 27-29, 2026!!

11 months ago 8 3 0 0
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Register to the next Int'l Deprescribing Journal Club on Nov 27!

Hear practical lessons & analyses from the SPPiRE trial, a cluster RCT assessing the effectiveness of a deprescribing intervention in older patients with high levels of polypharmacy in Irish primary care.
๐Ÿ‘‰ tinyurl.com/39seezfu

5 months ago 6 3 1 2
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๐Ÿ“ข Exciting news!

Selected articles from our Antimicrobial Viewpoints series will now be co-published in CMI Communications, @escmid.bsky.social's open-access journal.

This collaboration will expand the reach and amplify the impact of these articles within the antimicrobial R&D community.

6 months ago 7 5 1 0

Attend our upcoming webinar to learn how taking several meds can affect our health and wellbeing, and how you can reduce your risk of experiencing med-related harms by asking five simple questions.

๐Ÿ”— Register and share this event with your network! us02web.zoom.us/webinar/regi...

6 months ago 1 1 1 0

Welcome to our newest members!!

6 months ago 1 0 0 0

Submissions close next week, October 15th! Donโ€™t miss your chance to showcase your work on an international stage at ICOD 2026.

Submit your abstracts here: events.decorporate.ca/ICOD2026/abs...

Conference info and submission guidelines available here: www.deprescribingnetwork.ca/icod2026

6 months ago 2 3 1 0
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See you there!!

6 months ago 0 0 0 0
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๐ŸŽ‰ Registration is now open for ICOD 2026!

Secure your spot to this unique event, an opportunity to connect with the international deprescribing community, showcase your work and learn from leaders in the field.

Early bird available until Jan 31st 2026: events.myconferencesuite.com/ICOD2026/reg...

6 months ago 2 2 1 2
Screenshot of Communicable & Breakpoints hosts Erin McCreary & Angela Huttner with guests Rob Fowler and Nick Daneman.

Screenshot of Communicable & Breakpoints hosts Erin McCreary & Angela Huttner with guests Rob Fowler and Nick Daneman.

The 2nd #Communicable & #Breakpoints collaboration drops on 19 Sept! Hosts @angelahuttner.bsky.social & @erinmccreary.bsky.social invite BALANCE trial leads Nick Daneman & Robert Fowler to discuss everything from the trial's humble start to its meteoric impact in clinical practice.
#IDSky #clinmicro

7 months ago 12 7 0 2
From medical editors: A call to the global infectious diseases and clinical microbiology community Each time a man stands up for an ideal, or acts to improve the lot of others, or strikes out against injustice, he sends forth a tiny ripple of hope.Robert F. Kennedy, Senior

๐Ÿ“ฃ Medical editors call for #action against the decisions being taken in the #USA undermining #medicine and #science, and international #coordination to preserve what has been built across borders.

#IDSky #Clinmicro #MedSky #Episky #publichealth #vaccines

www.cmi-comms.com/article/S295...

1 year ago 67 33 3 6
CMI Comms editors at their Rome meeting

CMI Comms editors at their Rome meeting

CMI Comms editors at their Rome meeting

CMI Comms editors at their Rome meeting

Annie Joseph and Emily McDonald at CMI Comms editorsโ€™ meeting

Annie Joseph and Emily McDonald at CMI Comms editorsโ€™ meeting

CMI Comms editors hard at work ๐Ÿ˜Š

CMI Comms editors hard at work ๐Ÿ˜Š

Very excited to be holding our editorsโ€™ meeting in Rome. Best editors ever.
@dremilymcd.bsky.social @erinmccreary.bsky.social @anniejoseph.bsky.social @marcbonten.bsky.social @gurujosh.bsky.social @josh-nosanchuk.bsky.social

7 months ago 12 3 0 1

Want to be an editorial fellow with us at CMI Comms? See below!

8 months ago 1 0 0 0