Language models transmit behavioural traits through hidden signals in data - Nature During model distillation, large language models can subtly transmit traits unrelated to the training data.

Nature research paper: Language models transmit behavioural traits through hidden signals in data
go.nature.com/42bl0t6

Europe unveils an antidote to a potential US tech “kill switch” European companies have introduced a Disaster Recovery Pack – a tech stack that would ensure organizations can continue critical operations in a scenario where a foreign vendor activates the “kill swi...

cybernews.com/tech/europe-...

Diversity-generating retroelements for programmable targeted hypermutagenesis - Nature Biotechnology Diversity-generating retroelements are engineered for directed evolution in E.coli.

🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...

Dissecting the genetic determinants of bacterial DNA degradation by bacteriophage T5 www.biorxiv.org/content/10.64898/2026.04...

Phage receptor prediction from genome sequencing alone. Bacterial receptor (blue) interacting with phage proteins (purple) is shown here

📣Huge preprint 🔔
Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Europeans' justified mistrust in Trump's war in Iran EDITORIAL. Several European countries declined the American president's request to help secure shipping in the Strait of Hormuz. Donald Trump alone bears responsibility for this situation, given his p...

"Several European countries declined the American president's request to help secure shipping in the Strait of Hormuz. Donald Trump alone bears responsibility for this situation, given his policy of fait accompli." www.lemonde.fr/en/opinion/a...

Human herpesvirus evasion of humoral immunity and implications for vaccine development Nature Reviews Microbiology, Published online: 13 March 2026; doi:10.1038/s41579-026-01295-xIn this Review, Otero et al. explore how human herpesviruses evade humoral immune responses and consider the resulting implications for developing effective vaccines and treatments for diseases caused by these common viral pathogens.

ICYMI: New online! Human herpesvirus evasion of humoral immunity and implications for vaccine development

Bacteriophage host prediction using a genome language model www.biorxiv.org/content/10.64898/2026.03...

Exploiting intracellular oncogenic proteins to release cytotoxins The success of antibody-drug conjugates has demonstrated the value of targeted delivery strategies for cytotoxic molecules. However, many oncogenic drivers remain inaccessible to antibodies due to…

🔓Check out this #OpenAccess research by Matthias Schild & Dennis Gillingham @unibas.ch in our latest issue exploiting intracellular oncogenic proteins for the intracellular delivery and release of cytotoxins #medchem🧪

Read it in full on our website🔽

Gene-modified pancreas cells offer hope for people with type 1 diabetes Proof-of-concept trial in a single patient shows that cells can survive transplantation without immunosuppression

A proof-of-concept trial in a single patient has shown that genetically engineered pancreas cells can survive transplantation without immunosuppression.

#chemsky 🧪

Sassy2: Batch Searching of Short DNA Patterns www.biorxiv.org/content/10.64898/2026.03...

Music even makes you blink to the beat Rhythmic tunes trigger synchronized eyeblinks and automatic bopping or swaying, new research suggests

Rhythmic tunes trigger synchronized eyeblinks and automatic bopping or swaying, new research suggests

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence | Journal of Virology On Monday, June 3, 2024, Dr. Anthony Fauci, former Director of the National Institutes of Allergy and Infectious Diseases and a dedicated public health professional for over 40 years, testified voluntarily before the House subcommittee investigating the COVID-19 pandemic. Among other topics, he was asked about the origin of SARS-CoV-2, the coronavirus that causes COVID-19. The hearing was often disrupted and marked by contentious, disrespectful, and unfounded calls for Dr. Fauci to be “prosecuted” and imprisoned for “crimes against humanity.”

Very interesting commentary:
"There is currently no verified scientific evidence to support the lab leak hypothesis (of the SARS-CoV2)" journals.asm.org/doi/10.1128/...

"During the reporting period, we (Bluesky) removed 3619 accounts for involvement in suspected influence operations. Most of these accounts were assessed as linked to foreign state-aligned actors, including actors likely operating from Russia ..." #foreigninterference

“Why Are We Funding This?” Long-standing myths about “silly science” have contributed to the reckless slashing of government-supported research.

Why government funding of basic research is essential to scientific progress🧪:

www.americanscientist.org/article/%E2%...

What will happen when “AI” reviewers meet “AI” editors? There must be publishers already doing this…
🧪

Shein : 25 % des colis hors textiles jugés non conformes lors d’un contrôle massif à l’aéroport de Roissy, selon les services de douane Parmi les irrégularités constatées, les douanes évoquent des contrefaçons et des marquages ou notices absents sur des produits cosmétiques et des appareils électriques. Ce bilan revoit à la baisse les chiffres précédemment annoncés par le gouvernement.

Shein : 25 % des colis hors textiles jugés non conformes lors d’un contrôle massif à l’aéroport de Roissy, selon les services de douane

Et il coupe le son Le briefing politique essentiel du matin, par Élisa Bertholomey, Anthony Lattier et Sarah Paillou. Par ANTHONY LATTIER Avec ÉLISA BERTHOLOMEY et SARAH PAILLOU Envoyez vos infos | Abonnez-vous gratu…

Enquête sur l'audiovisuel public en stand-by, hypothèse du 49.3 et municipales en Savoie sont au menu de Playbook Paris, concocté par @anthonylattier.bsky.social.

Recent discoveries on the acquisition of the highest levels of human performance Scientists have long debated the origins of exceptional human achievements. This literature review summarizes recent evidence from multiple domains on the acquisition of world-class performance. We re...

Really interesting research showing that while ultra-specialization in a single discipline might lead to better results early in one’s career, multi-discipline training and practice pays off big time in the long run. This applies to a range of professions from scientists to athletes and more

Une étude dévoile la découverte d'une alternative naturelle à l'Ozempic plus efficace et sans ses effets indésirables Certains microbes intestinaux pourraient révolutionner notre compréhension des mécanismes métaboliques liés au diabète de type 2 en influençant les signaux hormonaux associés à l'envie de sucre.

www.science-et-vie.com/corps-et-san...

The changing roles of Escherichia coli Nature Microbiology - Richard Lenski traces the legacy of Escherichia coli and how science is evolving to use this model organism in new ways.

"The changing roles of Escherichia coli" -- a short essay by yours truly.

rdcu.be/eVtXT

Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance Nature Communications - Phage therapy shows promise for treating bacterial infections, including those resistant to antibiotics, but its development faces scientific and regulatory hurdles. This...

This paper highlights regulatory and evidence gaps slowing phage therapy, contrasting Belgium’s personalised approach with US fixed-phage RCTs. Stronger clinical data, better manufacturing capacity, & global coordination are key to moving phage treatments forward. #AMR
www.nature.com/articles/s41...

The A.I.-Profits Drought and the Lessons of History Like the steam engine, electricity, and computers, generative artificial intelligence could take longer than expected to transform the economy.

A recent M.I.T. study found that 95% of companies that had invested in A.I. tools were seeing zero return.

Temperature as a Driver of Phage Ecology and Evolution Bacteriophages (phages) are virtually ubiquitous and play a fundamental role in the ecological and evolutionary dynamics of their bacterial hosts. While phages are found across many thermal environmen...

Happy to see this phenomenal review led by Sam Greenrod with @kayla-king.bsky.social finally out in the world!

www.annualreviews.org/content/jour...

Phage quest: a beginner’s guide to explore viral diversity in the prokaryotic world Abstract. The increasing interest in finding new viruses within (meta)genomic datasets has fueled the development of computational tools for virus detectio

Interesting paper on bacteriophage genomics and bioinformatics

'Phage quest: a beginner’s guide to explore viral diversity in the prokaryotic world' by @sebwielgoss.bsky.social and colleagues

academic.oup.com/bib/article/...

Introducing Ada: the new AI training assistant. Explore on-demand bioinformatics training with Ada, your training AI assistant.

Introducing Ada: the new AI assistant from EMBL-EBI Training. We created our training chatbot, Ada, to make it easier and more engaging for users to find the right on-demand training resources from our broad catalogue of training: www.ebi.ac.uk/training/ada

#AdaLovelaceDay #bioinformatics

🧬🖥️

Two intensive sampling periods of oyster-associated vibrio and their phage, 4 years apart, and many surprises. Despite being washed by the Atlantic, wide tides, and vibrio (almost?) disappearing most of the year, we can find the exact same virulent phages 4 years later (down to 0 SNP)! preprint👇

Josephine Quinn · At the Institut du monde arabe: ‘Trésors sauvés de Gaza’ This show has excited controversy: should we even be talking about damage to antiquities in the context of so much...

At the Institut du monde arabe www.lrb.co.uk/the-paper/v4...