Exciting news: The Einstein Center for Early Disease Interception (EC-EDI) has received €6M in funding from @einsteinberlin.bsky.social
In this interview, the 2 EC-EDI spokespeople—MDC-BIMSB Director Nikolaus Rajewsky & Leif Erik Sander (Charité/BIH)—discuss the initiative: bit.ly/4qp39t2
#MDCBerlin
🔬 Join Human Technopole!
🧠 Our @ilegnini.bsky.social Group seeks a #Postdoc in Molecular Systems Biology to study genetic–environmental interactions in early neurodevelopment.
Apply by 30 Nov 2025 👉 careers.humantechnopole.it/job/Postdoc-...
Photo of the Alexanderplatz train station, showing a big rounded structure with glass, and red letters spelling ALEXANDERPLATZ. In the background a cloudy, gloomy sky, with the big Berlin TV tower. It looks like the tower is sprouting out of the train station, but it stands behind it.
Arrived in Berlin for the 3rd Young Scientist Cancer Congress.
Hope to see some of you there!
#YS2C
Four people standing in front of an audience in what appears to be a lecture hall. One is talking into a microphone, the other three are each holding a microphone and note cards.
Several dozen people sitting inside a large lecture hall. Most are facing the stage with four people on it, while a presentation is visible on a screen above the stage. Steps are leading away from the camera towards the stage.
Two people with microphones are standing on a stage in what appears to be a lecture hall.
Eight people standing in front of an audience inside a lecture hall. There is a presentation above them and a banner hanging from the ceiling showing the logo of the Max Delbrück Center.
We believe in fostering a community through exchange, dialogue, and mutual respect. 💙
Our "Town Hall Meetings" are a cornerstone of #mdcBerlin's culture. Colleagues from all over the institute come together to share ideas, ask questions, and celebrate progress. Today’s theme: Innovation @ Work
Dr. Jane Goodall, 1934-2025
An exceptional scientist, and a singular woman in science
#WomeninScience 🐒
www.nytimes.com/2025/10/01/o...
Join us for the hybrid GSCN Stem Cell Club on 2 Oct. at 16:15 h online: all info here: www.gscn.org
We have developed a new workflow to map whole human organs at single-cell resolution, while integrating spatial transcriptomics, proteomics, and metabolomics.
We applied this workflow to map precancerous lesions of the fallopian tubes.
More here: www.biorxiv.org/content/10.1...
White text on a black background: For me, the most inspiring part was seeing how many women are now leading the field of cancer research. I’ve attended conferences before, but this time, it felt different; there was a strong presence of women not just as attendees, but as keynote speakers, session chairs, and award recipients. It made me pause and realize how much the landscape is changing. As a young woman in science, it felt both empowering and motivating. It reminded me that we’re not just contributing, we’re also shaping the future of this field in a real and visible way.
As conference organisers, we just love to receive feedback like this anonymous comment from a trainee at our recent #EACR2025 Congress in Lisbon 😊
#WomeninSTEM #WomeninScience 🧪🔬👩🏻🔬👩🏼💻👩🏾⚕️👩🔬👩🏿🔬
@helloeacr.bsky.social
A collaborative effort: 🇩🇪 🇵🇱 🇫🇷 🇮🇹 🇬🇷 🇮🇱 🇷🇴 🇵🇹 🇨🇭
Many thanks to the whole
@N_Rajewsky lab,
@nukappa.bsky.social,
@danilexn.bsky.social, our institutions
@mdc-bimsb.bsky.social, @mdc-berlin.bsky.social, and personally to @DeutscheKrebshilfe for their generous support.
🎯 Tumor-derived TGFβ initiated TME remodeling: → iCAFs → macrophage recruitment
💪 Later, myCAFs remodeled ECM & interacted with EMT tumor cells
These niches are conserved in human TNBC PDXs and functionally validated.
📸 Tumor and stromal cells form spatially organized neighborhoods.
Aligning tumors by progression revealed how cell states, signaling, and ECM features remodel dynamically at the tumor–stroma interface.
🐁 Our model develops asynchronous tumors across glands. Using Open-ST and snRNA-seq, we profiled 100+ ducts in situ and treated them as replicates reconstructing tumor evolution from healthy tissue to invasion in native context.
We’re happy to share our new preprint form
@N_Rajewsky, with @tmpentimalli.bsky.social i.bsky.social @Ilan Theurillat
lab! 🎉
🧬 Spatiotemporal atlas of tumor–stroma crosstalk in a new TNBC model. Spatial transcriptomics (Open-ST), snRNA-seq, and functional validation.
🔗 biorxiv.org/content/10.1...
Spatiotemporal dynamics of tumor microenvironment remodelling www.biorxiv.org/content/10.1101/2025.07....
🔷 @www.helmholtz.de is building powerful #AI for science. 🔷
From cells to solar tech, Foundation Models help tackle complex data across various fields.
1️⃣2️⃣ centers, including the #mdcBerlin, are working on 7️⃣ pilot projects to make this technology work for science and society.
More: 👇 #Helmholtz30
Evidence for a previously overlooked route for microplastics to enter crops and reach plant tissues has implications for ecology and human health
https://go.nature.com/4iblIwc
Excited to introduce Malva publicly for the first time - our sequence-centric search engine for instant exploration of spatial and single-cell data at unprecedented scale.
#bioinformatics #singlecell
These are extremely challenging times for early-career faculty. Here is my office's small contribution to make their hard and important work a bit easier:
Download our curated and comprehensive database of funding opportunities for early-career faculty.
Here: research.jhu.edu/rdt/funding-...
Speaker lineup for stand up for science - Bill Nye, Dr. Atul Gawande, Dr. Phil Plait, Dr. Michael Mann, Dr. Itai Yanai Dr. Francis Collins, Dr. Victor Ambros, Dr. Nate Brought, Bill Nelson, JD Dr. Ticora V Jones, Dr. Gretchen Goldman, Dr. Haley Chatelaine Dr. Bonnielinn Swenor, Dr. Allison Agwu, Dr. Patrick Sullivan, Andrew Eneim Dr. Nathaniel Kupperman, Bridget Nelson, MPH, Samantha Jade Duran Denali Kincaid, Connor Phillips, Gabriella Amaya, Emily Whitehead Sarah Aleman Senator Chris Van Hollen (MD), Rep. Bill Foster (IL-11) Rep. Suhas Subramanyam (VA-10), Rep. Jamie Raskin (MD-8) Rep. Glenn Ivey (MD-4), Former Rep. Fred Upton (MI-6)
SPEAKER LINEUP FOR STAND UP FOR SCIENCE ☀️
Here's our list of current speakers—and it's still growing! Come tomorrow to hear some amazing speakers talk about science, their experiences, and the future.
#standupforscience2025
ONLINE NOW! @naturecancer.bsky.social
'Spatially resolved transcriptomics and graph-based #deeplearning improve accuracy of routine #CNStumor #diagnostics'
✏️By Dieter Henrik Heiland & Felix Sahm and colleagues
🔗 www.nature.com/articles/s43...
#spatialtranscriptomics
it is not β-Catenin but rather a mysterious gene called CTNNB1 :D
A microscopic image of cancer cells in shades of purple, overlaid with two hashtag boxes: #WorldCancerDay written in white letters on a dark magenta text box at the top, #UnitedByUnique in a light pink box at the bottom.
Each cancer is different, and so are the specific treatment options. "Onconaut," an #AI-based tool developed by #mdcBerlin's @al2na.bsky.social and his team, is designed to navigate through the maze of options more efficiently.
More: www.mdc-berlin.de/news/news/na... #WorldCancerDay #UnitedByUnique
🎗️ Cancer is often described as an “evolving disease” due to its ability to adapt and progress over time.
#WorldCancerDay
Mammary tumor tissue stained with collagen (green) and nuclei (red)
Are you working on #ECM or mechanobiology in the mammary gland or in breast cancer? Together with Jason Northey we are guest editing a collection on the topic for the Journal of Mammary gland biology and Neoplasia. Submission of articles is now open! link.springer.com/collections/...
Salon Sophie Charlotte January 18, 2025
Science meets society: How do we deal with change?
Join us at #SalonSC at @bbaw.bsky.social – Nikolaus Rajewsky and Katja Simon will share insights:
⚕️ Future Medicine
🧬 Life, Aging, and Death of Our Cells
🗓️ 18.01.2025, Markgrafenstr. 38, 10117 Berlin
Program: salon.bbaw.de
