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Weekly reads 23/3/26 Memory, models, and massive data: rethinking cancer across scales

Weekly reads 23/3/26:
Memory, models, and massive data: rethinking cancer across scales

open.substack.com/pub/behindth...

#CancerResearch #SingleCell #SpatialOmics #ComputationalBiology #SystemsBiology

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Resolve cellular heterogeneity with Novogene Single-Cell RNA Sequencing (scRNA-seq). Using 10x Genomics Chromium and Illumina, we profile expression at individual cell level for immunology, development, cancer & beyond. #scRNAseq #SingleCell #Transcriptomics https://tinyurl.com/bdwdypby

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Massive thanks to our global partners for the strategic alignment and hands-on #SameCellBiology sessions.
Huge shoutout to our guest speakers from @icepfl.bsky.social & #DTU for showcasing the incredible potential of the #FluidFM OMNIUM. The future of #SingleCell research is here! 🔬🚀 #CellBiology

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We are now on Substack!

Come find us at epigenometech.substack.com for our long-form pieces!

#EpigenomeTech #Blogs #Substack #PairedTag #SingleCell #Multiomics #Chromatin

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New atlas shows how adult brain cells retain traces of their development A new study from Karolinska Institutet and SciLifeLab presents a detailed map of how gene activity is regulated in individual cells of the adult human brain and spinal cord. Published in Nature Neuros...

New atlas shows how adult brain cells retain traces of their development. 🧪

“For this #SingleCell #epigenomic mapping of the human brain, extensive #DNAsequencing was required,” says @gocastelobranco.bsky.social

More here ↓
www.scilifelab.se/news/new-atl...

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scientific image. Text: "Chaos in lymph nodes promotes cancer"

scientific image. Text: "Chaos in lymph nodes promotes cancer"

In aggressive #lymphomas, inflammatory messengers reprogram the ​“conductors” of the immune system, causing lymph node structure to collapse. A team led by @simonhaas.bsky.social describes this process in ​“Nature Cancer” using #singlecell and spatial analyses: www.mdc-berlin.de/news/press/c...

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JIDApril2026: MERFISH walkthrough of human sebaceous gland showing transcripts of 278 distinct genes
JIDApril2026: MERFISH walkthrough of human sebaceous gland showing transcripts of 278 distinct genes YouTube video by Journal of Investigative Dermatology (JID)

Take a look at the April issue cover video
youtu.be/_06MjVNNv9s

This video demonstrates the interactive exploration of a #MERFISH skin tissue section using the MERSCOPE Visualizer software. Related article: Düz et al - doi.org/10.1016/j.ji...
#dermsky #SkinBiology #HumanSkin #SingleCell

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Single-cell sequencing reveals unexpected protist diversity Scientists developing a single-cell sequencing pipeline at Earlham Institute have revealed previously unknown diversity from a group of free-living protists closely related to the parasites that…

💬 “With developing technologies, such as spectral cell sorting, we’re capable of capturing visual as well as omics data from individual cells, which when combined with automation and other tools, will help accelerate these analyses."

🆕 #Singlecell sequencing reveals unexpected #protist diversity 👇

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We offer an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA and epigenetic marks - our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw

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Norwich Single-Cell and Spatial Symposium 2026 Bringing together the international single-cell and spatial community for a two-day discussion across model and non-model systems.

Early-bird registration is open for our symposium bringing together researchers applying #singlecell and #spatial methods across the tree of life, with talks including:

🦠 #microbe-host interface
🌱 plant-microbe interactions
🧠 disease states at single cell resolution

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Bei aggressiven #Lymphomen programmieren #Entzündungsbotenstoffe das Immunsystems um – deshalb bricht die Struktur der #Lymphknoten zusammen. Diesen Prozess hat ein Team um Simon Haas erstmals mit Einzelzell- und räumlichen Analysen entschlüsselt. #SingleCell

👉 www.bihealth.org/de/aktuell/c...

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Working with single-cell #RNAsequencing data?
Discover how bioinformatics analysis can reveal the hidden insights in your data - request our sample single-cell analysis report today at www.fiosgenomics.com/request-a-sample-report-...

#singlecell #RNAseq #bioinformatics #dataanalysis

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New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y

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Please join us on Thursday this week for the next webinar in the series “Towards a Human Exposome Atlas” on 26 March at 09:30-11:00 EDT | 13:30-15:00 GMT.
This webinar will focus on microplastics.
Please register at buff.ly/MV74YmE
🖥️ 🧬 #Genomics #Exposome #SingleCell

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Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i

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Cells don’t exist in isolation, why should your data? Context is everything, and #SpatialOmics26 reveals what others miss.
Ready to disrupt the field? Submit your abstract by April 20: vibbio.tech/4s69iLR

#SpatialOmics, #SingleCell, #Omics, #multiomics, #VIBConf

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#Macrophages are essential for this process but how they are instructed inside the injured heart remaines unclear. We wanted to understand the local signals that push them towards regeneration. So we combined #singlecell RNA-seq with #spatial #transcriptomics to map the regenerating hearts.

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Single-cell sequencing reveals unexpected protist diversity Scientists have revealed previously unknown diversity from a group of free-living protists closely related to the parasites that cause sleeping sickness.

🆕 Researchers from the Earlham Institute and @biology.ox.ac.uk developing #singlecell pipelines for #protist sequencing have discovered three previously unrecognised lineages of the protist Bodo, each with its own bacterial endosymbiont.

@neilhall.bsky.social | @sallywarring.bsky.social 💻🧬🦠

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Epigenetics News - New map reveals how adult brain cells remember their origins

News - bit.ly/4sZvcQN Nat Neurosci Study - go.nature.com/3NIRyHn

Gonçalo Castelo-Branco (Karolinska Institutet)

#Epigenetics #SingleCell #Development
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Hi-res insights without cell sorting; epigenometech.com

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Weekly reads 16/3/26 Rewiring cancer biology across scales: from 3D genomes to microbial niches

Weekly reads 16/3/26:
Rewiring cancer biology across scales: from 3D genomes to microbial niches

open.substack.com/pub/behindth...

#CancerResearch #SingleCell #SpatialOmics #Immunology #ComputationalBiology #AI

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New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit

Fully compatible with 10x Chromium® (ATAC), Fluent PiP-seq®, or BD Rhapsody

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4lquJDv

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Learn more about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag & Paired-Tag, which provides comparisons to other methods and bioinformatic insight

Learn more here: bit.ly/4r7CGRD

#Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag

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