✨New issue✨

Check out the latest in #Metabolism research from across all disciplines.

Read about #AdiposeTissue, #EVs, #Incretins, #Immune cells, #LiverMetabolism, #MitochondrialMetabolism, #SpatialOmics, #Tumorbiology and many more topics! 🧪

http://dlvr.it/TRmC3C

🤩Looking forward to welcoming Wilfred Van Ijcken (Element Biosciences) to our Spatial Omics conference in Brugge.

Join the conversation on the latest in spatial biology and genomics.

Submit your abstract by 20 April 2026 to be a part of the programme!

#SpatialOmics #Genomics #LifeSciences

Our Harpy paper is now published in Bioinformatics 🎉

Harpy is a scalable spatial omics analysis library built with Saeyslab & VIB Spatial Catalyst, integrating with SpatialData, AnnData, Scanpy, and Squidpy.

Check it out! 👇

academic.oup.com/bioinformati...

#SpatialOmics #Bioinformatics

Join us for #EMBOBuildNetworks at EMBL Barcelona to meet researchers working at the intersection of engineering and vascular biology and discuss the latest applications of cutting-edge techniques in #spatialomics, advanced #imaging, and #AI. 🔬🥼

Register by 1 April: s.embl.org/evb26-01-bl

Cells don’t exist in isolation, why should your data? Context is everything, and #SpatialOmics26 reveals what others miss.
Ready to disrupt the field? Submit your abstract by April 20: vibbio.tech/4s69iLR

#SpatialOmics, #SingleCell, #Omics, #multiomics, #VIBConf

Weekly reads 16/3/26 Rewiring cancer biology across scales: from 3D genomes to microbial niches

Weekly reads 16/3/26:
Rewiring cancer biology across scales: from 3D genomes to microbial niches

open.substack.com/pub/behindth...

#CancerResearch #SingleCell #SpatialOmics #Immunology #ComputationalBiology #AI

MSInet: A Self-Supervised CNN Framework Integrating Global and Local Context for Robust Mass Spectrometry Imaging Segmentation Mass spectrometry imaging (MSI) enables label-free molecular mapping in tissues but presents challenges for spatial segmentation due to high dimensionality, nonlinear spectral variation, and tissue he...

What's your biggest segmentation challenge?

🧠 Complex brain anatomy (many subregions)
🔬 Tumor heterogeneity (cancer vs. necrosis vs. healthy)
📊 Choosing cluster numbers (k=?)
🌀 Fragmented results

pubs.acs.org/doi/10.1021/...

#MassSpec #SpatialOmics #DeepLearning #Metabolomics

(4/4)

Today, the #DukeMGC is celebrating our 500th @10xgenomics.bsky.social #Xenium sample! From our first run in March of 2023 to now, we've learned a lot and generated data for many publications 🧬

For more info on our #SpatialOmics services, see dmpi.duke.edu/cores/molecu...

#SpatialTranscriptomics

📣 TOMORROW! @jsb-ucla-bsky.social presents "Definitions and Applications of Spatial Niches in Spatial Omics Data Analyses: A Summary and Discussion" #ENAR2026 #SpatialOmics

Wonderful discussions and inspiring science at the #SingleCell and #SpatialOmics Symposium in Helsinki.

We were happy to attend, share our work, and also receive the award for Best Poster and Presentation.

@turkubioscience.bsky.social @inflames-flagship.bsky.social @utu.fi

30 speaking slots are available from the submitted abstracts with at least half dedicated to #ECR and #EMCR speakers. #SingleCell #Genomics #SpatialBiology #SpatialOmics #HumanCellAtlas

Excited to share currently confirmed speakers for HCA Asia 2026 (lnkd.in/gEQPj3Gk)!

#SingleCell #Genomics #SpatialBiology #SpatialOmics #HumanCellAtlas #SingleCell #transcriptomics #multiomics #Spatial_transcriptomics

@ozsinglecell.bsky.social
@lornegenome.bsky.social

We’ve kicked off our 5-day journey on #SpatialTranscriptomics with Tancredi Pentimalli and an amazing international group of attendees!

Excited for an inspiring week of learning and hands-on sessions ahead!

@bioconductor.bsky.social
#SingleCell #Genomics #Bioinformatics #RStats #SpatialOmics

Integrating Ambient Ionization Mass Spectrometry Imaging and Spatial Transcriptomics on the Same Cancer Tissues to Identify RNA–Metabolite Correlations Innovations in spatial omics have advanced disease research, but spatial transcriptomics (ST) and spatial metabolomics remain separate. We present a novel method integrating DESI-MSI spatial metabolo...

DESI+ST simultaneously profiles metabolites, lipids, and mRNA on the same tissue section at matching spatial resolution, eliminating inter-section variability.
#singlecell #MassSpec #Metabolomics #SpatialOmics

onlinelibrary.wiley.com/doi/10.1002/...

Weekly reads 16/2/26 From ecDNA to epigenomic priming: modeling what averages miss

Weekly reads 16/2/26:
From ecDNA to epigenomic priming: modeling what averages miss
open.substack.com/pub/behindth...

Overall theme: Averages hide, structure reveals.

#SingleCell #SpatialOmics #CancerBiology #ComputationalBiology #MultiOmics #AIinBiology

Spatial Omics Expert Jasmine Plummer Aims to Broaden Its Reach Jasmine Plummer hopes to make spatial omics more powerful and accessible to the scientific community.

Honored to be featured in The Scientist discussing how we’re working to broaden the reach of spatial omics-to make these powerful technologies more accessible & integrated across research communities.
#SpatialOmics #SingleCell #Multiomics #PrecisionMedicine #CancerResearch #spatialbiology #tissue

Spatial proteomic image of a lung tumour depicting the immune niche (blue, pink, purple cells) in which CD14+CD4+ T cells reside within the tumour. Tumour cells are coloured in grey.

Using spatial multi‑omics, WEHI scientists have uncovered an unusual population of CD14⁺CD4⁺ T cells in lung tumours, with higher levels linked to poorer patient outcomes.

New study out in @cp-cellrepmed.bsky.social

👉 www.cell.com/cell-reports...

#Cancer #SpatialOmics #TCells

Weekly reads 2/2/26 How space, context, and uncertainty reshape cancer and single-cell biology

Weekly reads 2/2/26 :
How space, context, and uncertainty reshape cancer and single-cell biology

open.substack.com/pub/behindth...

Big theme: space + context + mechanism > black-box scale alone.

#SpatialOmics #SingleCell #CancerBiology #TumorMicroenvironment #AIinBiology #Immunology

Introducing Spatial Sampler, the ‘cheat sheet’ to answering biological questions — Australian BioCommons A new tool is available to help researchers quickly answer important questions about their spatial omics data. This new resource, called Spatial Sampler, collates example R scripts for a variety of co...

Struggling to find workflows that test real experimental questions? Introducing Spatial Sampler - a collection of 'How-To' guides to fast-track your #SpatialOmics analysis. Developed by Sarah Williams (QCIF) to fill the gap between basic QC and complex answers www.biocommons.org.au/news/spatial...

Weekly reads 26/1/26 When simple representations outperform complex models in biology

Weekly reads 26/1/26:
When Simple Representations Outperform Complex Models in Biology

open.substack.com/pub/behindth...

Big takeaway: biology gets clearer when models respect geometry, hierarchy, and context.

#SingleCell #SpatialOmics #CancerBiology #ComputationalBiology #Genomics

Spatial Biology Update - DeciBio is developing a new report focused on the real-world perspectives of end users of spatial omics technologies. For more information, contact Rebecca Burnham, PhD #spatialbiology #spatialomics #singlecell #multiomics

Fusing future science tech with complex genetic data for faster, more precise diagnostics at the Colonial Foundation Diagnostics Centre with The Royal Melbourne Hospital💡🧬🚀

👇
www.wehi.edu.au/news/ending-...

#Diagnostics #ScienceTech #AI #ML #SpatialOmics #InflammatoryDiseases

Weekly reads 19/1/26 Multimodal integration, interpretability, and robustness in spatial biology

Weekly reads 19/1/26:
Multimodal integration, interpretability, and robustness in spatial biology

open.substack.com/pub/behindth...

Main theme: multimodal data is powerful, but only if it’s aligned, interpretable, and batch-aware.

#SpatialOmics #SingleCell #RegulatoryGenomics #AI

🧬 Join the next talk with Ralf Jungmann (Max Planck Institute of Biochemistry) on #DNA nanotechnology and #spatialomics.

Register by 11 February 👉 humantechnopole.it/en/training/... #HTseminars @florianjug.bsky.social

Join the LinkedIn Group "Spatial Biology Pioneers" if you are in the spatial multiomics field #spatialomics #singlecell #multiomics linkedin.com/groups/13906...

Curious about spatial omics and hands-on multi-omics analysis? 🧬
Explore spatial platforms, learn SPArrOW/Harpy & Cardinal, and discover multi-omics integration strategies at our summer school.
⏰ Deadline to register: 2nd February
#SpatialOmics #SpatialBiology #MultiOmics #Transcriptomic #Proteomics

Weekly reads 5/1/26 Standardizing, disentangling, and interpreting cells in space

Weekly reads 5/1/26:
Standardizing, disentangling, and interpreting cells in space

open.substack.com/pub/behindth...

#SingleCel #Epigenomics #SpatialBiology #CRISPR #CellCellCommunication #AIinBiology #SpatialOmics

Epigenetics Review - Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications bit.ly/4aY7a39

Linghua Wang reporting in Cancer Cell

#Epigenetics #Review #SpatialOmics
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Discover the breakthrough at epigenometech.com

That's a wrap on another year in the Gregory lab! 2025 was filled with many hours of hard work in the lab & R Studio, with some fun along the way.

Cheers to 2026 from all of us - we can't wait to show you what we've been working on this year! 🥂🧬🧠

#SingleCell #SpatialOmics