Want to see #DukeMGC #Xenium data in action? Check out our publications here: dmpi.duke.edu/cores/molecu...

Today, the #DukeMGC is celebrating our 500th @10xgenomics.bsky.social #Xenium sample! From our first run in March of 2023 to now, we've learned a lot and generated data for many publications 🧬

For more info on our #SpatialOmics services, see dmpi.duke.edu/cores/molecu...

#SpatialTranscriptomics

Presenting the #DukeMGC poster from #AGBT26

'Beyond 'Black Box' Analysis: A platform-agnostic guide for non-formalin fixed #SingleCell RNA sequencing'

For more information, check out our preprint: www.biorxiv.org/content/10.6...

This afternoon, come check out #DukeMGC data at #AGBT26 4:45-6:15, poster #472!!

Work from the #DukeMGC will be on display at #AGBT2026:

Tuesday 1:30-3:30, poster #401

Wednesday 4:45-6:15, poster #472

Come find us to chat about our data! 🧬

#AGBT #SpatialTranscriptomics #SingleCell #Benchmarking #LongReadSequencing

We are thrilled to share the 1st pub out of the #DukeMGC. Congrats to Lab Analyst Ellora Haukenfrers' on your 1st first author paper!

We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'

#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...

Today, #DukeMGC gave a talk & poster presentation on our available services at the #Duke Precision Genomics Collaboratory! We love the opportunity to share the work we do... 🧬🧠

Interested in learning more about MGC services? Please visit our website: dmpi.duke.edu/cores/molecu...

Please vote for the #DukeMGC wet lab's costume ('That Rat’s a Real Muenster’) in the 2025 Duke Costume Contest!! Each like = 1 vote

www.facebook.com/workingatduke/

Hope you weren't planning any rat studies soon...

This year, the #DukeMGC dressed up as a lab rat & cheese!! Happy #Halloween & stay cheesy everyone 🧀🐀🎃

Every year, the #DukeMGC dresses up for Halloween... any guesses what we're cooking up this year? 🎃👻🐈‍⬛🧬

The Gregory Lab presents our own production of #EmilyinParis! #DukeMGC Research Analyst, Emily, is shaking things up this week in #Paris 😍

As one of our spatial team major players she knows "Life (and #spatialomics) is like a croissant. You have to embrace the layers." 🧬🥐

Thank you to @10xgenomics.bsky.social for having #DukeMGC at the Research Triangle Park User Group Meeting! #RTP

Wonderful to see so many familiar faces and meet everyone. We can't wait to see what this year holds... seems a higher SCALE of flex is coming soon 😉🧬
#singlecell #spatialomics

DUX4-stimulated genes define an antiviral defense program in human placental trophoblasts Human trophoblasts activate a DUX4-driven antiviral program in response to herpesvirus infection. This defense pathway, distinct from canonical immune resp

New publication out of the #CoyneLabatDuke, with #DukeMGC data 🧬

rupress.org/jem/article/...

10/9/25 9am-4pm see #DukeMGC services at the @10xgenomics.bsky.social #RTP User Group Meeting #10xRTPUGM 🧬

Talks about:
- #GEMX Flex
- Validated #singlecell automation protocols
- #Visium HD larger capture area & poly-A
- #Xenium RNA and protein on 1 slide

pages.10xgenomics.com/ugm-2025-10-...

Defining cellular diversity at the swine maternal–fetal interface using spatial transcriptomics and organoids Understanding porcine placental development has been hindered by the lack of in vitro models that reflect its cellular heterogeneity. This study develops a swine trophoblast organoid model that mimics...

New paper with #DukeMGC #SpatialTranscriptomics & #SingleNuclei data - check it out! 🧬
journals.plos.org/plosbiology/...

On 9/16 at 2PM, join #DukeMGC & @10xgenomics.bsky.social to explore how #VisiumHD and #Xenium platforms are advancing #spatialbiology!

REGISTER HERE: docs.google.com/forms/d/17HI...

Contact bryan.hess@10xgenomics.com or #DukeMGC Assistant Director, karen.abramson@duke.edu with any questions.

Inside TB's Hidden Cities Advanced genetic sequencing reveals the cells behind many persistent tuberculosis infections and provides a map of exactly where these cells live, pointing the way toward new treatments.

New article out of @dukemedschool.bsky.social ft #DukeMGC #SpatialTranscriptomics & #SingleNuclei data medschool.duke.edu/news/inside-...

LinkedIn Login, Sign in | LinkedIn Login to LinkedIn to keep in touch with people you know, share ideas, and build your career.

We have a freshly launched #LinkedIn group for the #DukeMGC 🧬💻🥂For more information on our available services, tips & tricks and new publications/preprints, click here... www.linkedin.com/groups/13357...

Tissue-Resident Macrophage and Dendritic Cell Cooperation Drives Type I IFN Immunity to Enteroviruses in the Liver Enteroviruses are major causes of neonatal morbidity and mortality, with echovirus infections commonly associated with severe disease, including acute liver failure. The human neonatal Fc receptor (hF...

New preprint out with #DukeMGC #scRNAseq data! 🧬🧪

Check it out: 'Tissue-Resident #Macrophage and #Dendritic Cell Cooperation Drives Type I #IFN Immunity to 4 #Enteroviruses in the Liver' by Emma Heckenberg & Duke's #CoyneLab www.biorxiv.org/content/10.1...

#singlecell #immunology

Do you want to run @10xgenomics.bsky.social #Visium or another #SpatialTranscriptomics project, but aren't sure how to prep and store your samples? 🧬🧠💻🧪

Check out #DukeMGC Visium project guidelines on our website at dmpi.duke.edu/cores/molecu...

MGC Spatial Omics | Duke Molecular Physiology Institute | Duke Molecular Physiology Institute Xenium Human GBM Image Courtesy of Simon Gregory

Planning a @10xgenomics.bsky.social #Xenium or other #SpatialOmics project, but aren't sure how to prep and store samples? 🧬🧠💻🧪

Check out #DukeMGC Xenium project guidelines on our website at dmpi.duke.edu/cores/molecu...

MGC Single Cell/Nuclei | Duke Molecular Physiology Institute | Duke Molecular Physiology Institute The 10x Genomics Chromium X platform partitions between 500-20,000 single cells/nuclei into Gel Beads-in-emulsion (GEMs), using a microfluidics-based instrument & nanoliter-scale gel bead technology. ...

Are you interested in a #singlecell or #singlenuclei projects but aren't sure how to preserve your samples? 🧠🧬🔬

Check out #DukeMGC project guidelines on our website's #scRNAseq page at dmpi.duke.edu/cores/molecu...

New collaboration out with #DukeMGC @10xgenomics.bsky.social #Visium data 🧬🔬💻

Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages Brain metastases occur in up to 40% of Stage IV breast cancer patients. The cerebellum is a frequent location for metastases in HER2-positive breast cancer patients, but the mechanisms for this are un...

Another Gregory lab collab, out now as a preprint!

'Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages', with #DukeMGC bioinformatician Khooshbu as 2nd author.

Congratulations to the whole team 🧬🔬💻⚕️

www.biorxiv.org/content/10.1...

Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD - Nature A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

New #publication out with #DukeMGC generated
@10xGenomics

#Xenium data from the Williamson lab - one of the first Xenium papers including #postmortem #PTSD samples! 🧠📷 #SingleCell #transcriptomic and #chromatin dynamics of the human brain in PTSD
www.nature.com/articles/s41...

Moments from the #DukeMGC... lab work is fun with friends 🧬🤩🔬🧫👏

Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction - Nature Communications MASLD is a growing global health concern. Here, the authors define a senescent hepatocyte gene signature (SHGS), demonstrate its clinical relevance, and identify senolytic therapies that selectively e...

Long term collab bw @dukemedschool.bsky.social & @boehringerglobal.bsky.social using #multispecies #SingleCell data from the #DukeMGC: 'Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction' 🧬🔬🧫⚕️
doi.org/10.1038/s414...

Redirecting

New collab out with Jennifer Zhang & Amy Petty of @dukemedschool.bsky.social #Dermatology Department! #scRNAseq performed by #DukeMGC

'Insights into #Keratinocyte and Immunologic Landscape in #Cutaneous #Graft-Versus-Host Disease through #SingleCellTranscriptomics' 🧬💻

doi.org/10.1016/j.xj...

2nd #DukeSCIRIP colloquium was a smash hit! Shoutout to #Gregorylab members for making today possible! Thanks to all attendees & our remaining sponsors... @dukecancer.bsky.social #CancerBio prog., #DukeMGC, #AkoyaBioscience, @elembio.bsky.social, #SingularGenomic , #ScaleBiosciences , and #Takara 🧬🧠

NEW PUB from a novel grant collab bw Gregory lab and
@theluftiglab.bsky.social
!! #SingleCell data generated by #DukeMGC from #ImmuneToleranceNetwork samples to detail the characterization of #ABCs & the putative role as #EBV vectors in progressive #MS 🧬🧫🧠🧑‍🔬
insight.jci.org/articles/vie...