Mitochondrial Autoimmunity Originating in the Liver May Drive Parkinson Disease Researchers discussed the probable link between primary biliary cholangitis (PBC) and Parkinson disease in a recent review.

Canadian researchers discussed the probable link between primary biliary cholangitis (#PBC) and #Parkinson disease in a recent review published in Current Opinion in Immunology.

Learn more: https://bit.ly/47OIveU

#RareDisease #PrimaryBiliaryCholangitis #ParkinsonDisease #Immunology

A visual representation of a phase 2 randomized trial of mezagitamab in primary immune thrombocytopenia.

Available therapies for immune thrombocytopenia are ineffective in some patients. Research evaluating mezagitamab is summarized in a new Quick Take video. nej.md/4snStLF

#Hematology #Immunology

Exciting discoveries in the gut biome's participation in immune response to cancer. #immunoengineering #immunology #immunotherapy

Macrophages self-generate and refine chemotactic gradients during migration towards complement C5a Macrophages don’t just follow chemoattractants to locate sites of infection, they can also create and sculpt them as guidance cues but the mechanisms remain unclear. This study shows that macrophages can extract directional information from their environment from a constant concentration of the C5a chemoattractant, self-generate a gradient and enhance guidance.

'These findings identify C5a degradation as a critical mechanism by which macrophages extract directional information fm their environment. Self-generated gradient formation, despite different mechanisms across species, emerges as a conserved & versatile strategy for immune navigation.'
#Immunology

China CD4 Antibody Market: Where Immunology Meets Scale

Get sample 👉www.marketsintrend.com/sample-report/8206-china...

China CD4 antibody market grows at ~8–9% CAGR, driven by HIV monitoring, diagnostics, and immuno‑therapeutics expansion.

#CD4Antibody #Immunology #CD4

A new, glycoengineered form of anti-CD20 monoclonal antibody, in treatment of multiple sclerosis
@taneuroldisord.bsky.social
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#neurology #immunology #drugdevelopment #medicalresearch #openaccess

Networking tip advising to start engaging early by following and replying to the event hashtag before sessions begin at Immunology 2026.

🔬 Excited for IMMUNOLOGY2026™ in Boston? Invite your colleagues to follow you during this premier #immunology event! Share your experience and use #IMMUNOLOGY2026™ or #AAI2026 to tag your posts. Download the AAI Events Mobile App today and make this your best meeting yet: https://ow.ly/pj4c50YH3U2

Endogenous glucocorticoids restrain gastric immunity, allowing persistence while preventing chronic inflammation, autoantibodies, dysplasia, and lasting cancer risk after infection.
Check it out! 🔗https://ow.ly/EvTt50YEJB2
🏷️#Immunology #Helicobacter

#ImmunologyNews he study shows that lipid-rich environments in RA joints can trigger a highly inflammatory form of cell death in immune cells...#research #immunology #science

Read more here: https://ow.ly/I7NN50YEMUi

Understanding this dynamic is essential to anticipate risks and prevent the next pandemic.

#H5N1 #Influenza #OneHealth #Zoonoses #Immunology #PandemicRisk #FoodSafety #Wildlife #Antarctica #GlobalHealth 9/10

@aai.org is so soon 💻🙈 If you’re a part of the #HIPC group and presenting a poster or talk, comment below or dm us! We would love to spread the word #AAI2026 #immunology

B cells enable autoreactive T cells to avoid suppression | PNAS Clinical trials and experimental observations have shown that B cells are essential for development of T cell–mediated organ-specific autoimmunity,...

This level of scientific ignorance is unacceptable. You cannot draw conclusions about antigen-specific Treg inhibition from in vitro assays when they do not align with in vivo suppression readouts.

#science
#immunology
#Tregs
#Foxp3

www.pnas.org/doi/10.1073/...

Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity Macrophages exert antitumorigenic activity through phagocytosis, but phagocytosis-enhancing therapeutics have not improved acute myeloid leukemia (AML) outcomes. To identify phagocytosis regulators,…

This is just bizarre. Companies spend billions developing anti-CD47 therapeutics, yet for at least one #cancer type, this “don’t eat me” signal blocks mouse but not human macrophages. No wonder it never worked in clinical trials.

#science
#immunology

www.science.org/doi/10.1126/...

We're still looking for a few more reviewers in #Immunology. Are you interested in trying out our new model of peer review?

#OpenScience #PeerReview

📢 Program now live!
Explore the schedule for the 18th International Conference on Complement Therapeutics and view accepted posters.
🧬 Program: aegeanconferences.org/conferences/...
🧾 Posters: aegeanconferences.org/conferences/...
#Complement #Immunology #BiomedicalResearch #Conference

Dive into the world of #immunology with the 2026 AAI Summer Immunology Courses! Learn from the best and connect with fellow enthusiasts. Whether you're just starting or looking to advance your expertise, we've got you covered.

🔗 https://ow.ly/gHl750YBbeK

#AAICourses #EducationAndSharingDay

New study finds that inhaled polypropylene nanoplastics damage the lung’s epithelial barrier, trigger cell death and inflammation, and interact with blood proteins in unexpected ways—with notable differences between males and females.
#Immunology #Nanoplastics #ROS
🔗 ino.to/BdWRKpL

Skull channels as gateways for immune surveillance of the brain The central nervous system (CNS), once considered immune privileged, is, in fact, protected by a dynamic immune compartment located in the meninges. These immune cells are crucial for brain protection, controlling neuroinflammation, and also supporting neural function. Recent studies show that meningeal immune cells, including myeloid and B cells, partly originate from the skull bone marrow, which communicates directly with the meninges via specialized skull channels identified in mice and humans. These channels allow immune cell trafficking and cerebrospinal fluid (CSF) exchange, positioning the skull marrow as a CSF-sensing niche. Therefore, understanding skull–meninges–brain interactions reveals a functional connection between bone marrow and the CNS, offering new insights into neuroimmune regulation and potential therapeutic strategies in neuroinflammatory conditions.

Skull channels as gateways for immune surveillance of the brain #immunology

Understanding how these cells behave is key to uncovering how kidney function is maintained and how it can be disrupted in disease.

#sciart #microscopy #kidney #cellbiology #immunology #biomedicalresearch #scienceisbeautiful #artinscience

Dual Role of Factor H-Related Protein 1 in IgA Nephropathy Kidney Injury - PubMed FHR-1 exacerbates kidney injury in IgAN by accelerating complement activation and inflammation. FHR-1_SCR1-2 effectively attenuated FHR-1-induced inflammation, demonstrating promising…

New study reveals FHR-1 as both a driver of complement-mediated injury in IgAN and a novel therapeutic target, reshaping disease biology and treatment strategies. #IgAN #Nephrology #ComplementSystem #Immunology #MedTwitter
buff.ly/giVErnc

Join us online for the MRC CoRE in Exposome Immunology AI in Immunology Workshop. Wednesday 6th May 2026.

🖥️🤖 AI in Immunology Workshop – FREE online tickets!

Join us online for the AI in Immunology Workshop, hosted by us along with @lydiabeckeriii.bsky.social and GJBRC. Featuring keynote talks, short talks and workshops.

Learn more & get your FREE online tickets ➡️ lnkd.in/eNRYnDjh
#AI #Immunology

Are interferons friend or foe in colorectal cancer?

They can enhance anti-tumor immunity—but also contribute to tumor progression and immune evasion.

A true double-edged sword in CRC.

Free read: dr.clintile.com/en/article/d...

PMCID: PMC11220628

#ColorectalCancer #Immunology

#Immunology #Dendriticcell #DGfI

Immunoferroptosis: ferroptosis meets tumor immunity and immunotherapy Ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has attracted considerable attention in tumor biology and cancer therapy. Beyond its intrinsic role in tumor suppression, ferroptosis greatly influences the tumor immune microenvironment. Ferroptotic tumor cells release damage-associated molecular patterns, oxidized lipid mediators, and nucleic acids, which can either activate or suppress antitumor immunity. Conversely, immune cells modulate tumor cell sensitivity to ferroptosis through the secretion of cytokines and metabolites. In this review, we summarize the current understanding of the interplay between ferroptosis and tumor immunity. Targeting ferroptosis may offer broad opportunities to enhance tumor immunotherapy.

Immunoferroptosis: ferroptosis meets tumor immunity and immunotherapy #immunology

🚨 Join our upcoming webinar!

Inborn Errors of Immunity in Latin America: from suspicion to treatment

📅 April 21, 2026
🕗 8:00 PM (Mexico City time)

🎓 Recertification credits (CMCP & CONICA)
🔗 Register now: us02web.zoom.us/webinar/regi...

#IEI #Immunology #PrimaryImmunodeficiency

🧒🦠 What drives #LongCOVID in children?

Our new @IrsiCaixa research in JCI Insight reveals:
🔹 Immune dysregulation
🔹 Reduced neutralizing antibodies
🔹 CCR6 as a potential biomarker (79% accuracy)

👉 A key step toward better diagnosis & treatments

🔗 doi.org/10.1172/jci....

#Pediatrics #Immunology

🩸 More insights into disease biology & pathogenesis in Chronic Myelomonocytic Leukemia

#CMML #Hematology #HemOnc #Leukemia #HEMEHUB #MyeloidNeoplasms #BoneMarrow #Monocytes #FlowCytometry #Immunology #AutoimmuneDisease #MedEd #ChronicMyelomonocyticLeukemia

Dr. Miriam Merad is a woman with chin-length black hair wearing a white long sleeve shirt and a cream-colored scarf. She is smiling at the camera, standing in front of a blurred background.

Dr. Miriam Merad (Icahn School of Medicine at Mt Sinai) will present "Macrophages Key Guardians of Tissue Health and Drivers of Diseases" at our next #Eberly Distinguished Lectureship in #Immunology! @pitt-pmi.bsky.social

See you Thurs., April 23rd at noon in the Assembly Auditorium or Zoom!

Few rooms left for the Innate Immunity Conference (Crete, Greece 🇬🇷)!
Early fee + abstracts (poster) + travel awards: Apr 15
Program: aegeanconferences.org/conferences/...
#InnateImmunity #Immunology #Conference

Few rooms left for the 7th Int’l Conference on Cytokines in Cancer (Crete, Greece 🇬🇷)!
Early fee + abstracts (poster) + travel awards: Apr 15
Program: aegeanconferences.org/conferences/...
#CancerResearch #Immunology #Cytokines