SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.

Encouraging research suggests SARS-CoV-2 mRNA vaccination may be linked with improved survival in some patients receiving immunotherapy for solid tumours, including NSCLC and melanoma. #CancerResearch #Immunotherapy #TCSC
www.nature.com/articles/s41...

Targeting Mettl8-Tcf1 axis promotes CD8⁺ TPEX differentiation and antitumor immunity. New study from Jiaxi Song, Dan Cui, Qizhao Huang, Jia Li, Fengyin Li (University of Science and Technology of China) and colleagues:
rupress.org/jem/article/...

#TumorImmunology #Immunotherapy

Adjuvant immunotherapy for muscle-invasive urothelial carcinoma: Considerations for targeting patients

Bladder Cancer
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#urology #cancer #oncology #biomarker #ctDNA #immunotherapy #openaccess

The prospects of CAR T-cell therapies in changing the therapeutic algorithm of neurologic autoimmunities
@taneuroldisord.bsky.social
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#neurology #inflammation #immunotherapy #medicine #openaccess

Stage 4 breast cancer after chemo can feel like a dead end… 

But immunotherapy could still be an option, especially with the right biomarkers.

www.placidway.com/answer-detail/571353/Is-...

 #fyp  #immunotherapy
#breastcancer

Breakthrough High-Throughput Platform Yields Fast-Acting Covalent Protein Drugs Research from Westlake University reveals a pioneering high-throughput platform for crafting fast-acting covalent protein therapeutics, enhancing their effectiveness.

Breakthrough High-Throughput Platform Yields Fast-Acting Covalent Protein Drugs #China #Hangzhou #Immunotherapy #Westlake_University #Covalent_Drugs

Exposing tumors: Why some cancers are especially hard to treat Some tumors go into

Some cancers are harder to treat because they hide from the immune system. This LJI article explains why “cold” tumors can be so stubborn and how researchers are trying to outsmart them. #CancerResearch #Immunotherapy #TCSC
www.lji.org/news-events/...

Antibiotics and Immunotherapy in Melanoma | Docwire News Antibiotic use during immune checkpoint inhibitor therapy may be associated with improved overall survival among patients with advanced melanoma.

What is the impact of #antibiotic use on #immunotherapy for #melanoma? Check out the results of a retrospective study from Dr Vincent Ma (@uwmadison.bsky.social) at the link!
#Dermatology #Oncology #SkinCancer

www.docwirenews.com/post/impact-...

Breakthrough CAR-T Cell Production Method Could Extend Cancer Remission and Advance HIV Cure Research BRONX, — Scientists from Albert Einstein College of Medicine have unveiled a new technique for producing CAR-T immune cells that may dramatically improve how long these engineered cells remain active in the body, potentially strengthening treatments for blood cancers and bringing researchers closer to long-term HIV control. The findings, reported in the journal Science Advances, …

Breakthrough CAR-T Cell Production Method Could Extend Cancer Remission and Advance HIV Cure Research #CancerResearch #CART #HIVCure #Medicine #Immunotherapy

Amyloid plaques, shown here in pink via a transmission electron micrograph of an Alzheimer's patient's brain. Image credit: Science Source/THOMAS DEERINCK, NCMIR

Reprogrammed #astrocytes clear #Alzheimers #plaques in mice. In PNAS Journal Club: https://ow.ly/MgWU50YCrrr

#AlzheimersDisease #AmyloidPlaque #immunotherapy #AdenoAssociatedVirus

STRIDE Regimen Shows PFS Benefit Alongside TACE and Lenvatinib in Embolization-Eligible Unresectable HCC | OncLive A trend toward improved OS was also observed when the dual immunotherapy regimen was added to TACE and lenvatinib in this patient population.

🧬 The STRIDE regimen (tremelimumab + durvalumab) combined with lenvatinib + TACE significantly improved PFS vs TACE alone in embolization-eligible disease in the phase 3 EMERALD-3 trial 📊
Read more ➡️ www.onclive.com/view/stride-...
#HCC #LiverCancer #Immunotherapy #Oncology

Promotional graphic showing a pink-orange San Diego skyline with text: “Let’s talk about your immunotherapy projects at AACR 2026 • San Diego, California” and the iRepertoire, Inc. logo.

Meet with us in booth #723 at AACR 2026 to learn how our seven-chain immune repertoire sequencing, immunophenotyping, and expert data analysis services can advance your immuno-oncology program.

Explore our services: irepertoire.com/immuno-oncol...

#AACR2026 #Immunotherapy

22-23 PHARMA - Fast and the curious This month: the NHS as a dystopian game of Tetris, the GLP-1 explosion and its impact on future meds, plus deep dives into AI in pharma, reproductive health, and Trump’s healthcare influence. Also, co...

#mRNAvaccines #GLP1 #obesity #CARTcelltherapies #oncology #PCSK9inhibitors #HepatitisC #Immunotherapy #checkpointinhibitors #RSVvaccines #Genetherapies #rarediseases #antivirals #Biosimilars #expandedaccess #biologics #HIV #Migraine #CGRPinhibitors #antifungals #precisionmedicine
zurl.co/3UDz7

Cai and Tang report a 26-year-old male with aggressive T-LGLL and a near tetraploid karyotype. After failing #chemotherapy, he achieved complete remission with Tislelizumab and Pentostatin. No relapse at 6 months suggests a new role for #immunotherapy in aggressive T-LGLL.
doi.org/10.59717/j.x...

Stay in the know with #SITC! Explore our upcoming events, webinars, and important dates by looking at our calendar. Learn More: https://sitcancer.org/get-involved/events/calendar #Immunotherapy

Researchers identified that CCR7 exhibits dual roles in HCC, promoting tumor progression yet enhancing immune response in stromal contexts, offering a #Biomarker for precision therapy and improved #Immunotherapy outcomes. @fudan-university.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

New research shows that adding CD28 signalling motifs to the CD3ζ chain boosts IL‑2 production and expansion of TCR‑engineered T cells, without reducing cytotoxicity. A promising step toward stronger TCR therapies for solid tumours.

Read here: vist.ly/4wxea

#Immunotherapy #TCells

Hanina et al. (2026) report on CAR T cells, engineered for enhanced sensitivity to CD70. The findings open new doors for solid tumor therapy by targeting even tumors with minimal CD70.
Check out the video!
#CancerResearch #Immunotherapy #CARTcells
youtu.be/Kit35JwsocQ

Cell Cycle-Related LncRNA-Based Prognostic Model for Hepatocellular Carcinoma: Integrating Immune Microenvironment and Treatment Response

This study introduces a risk score model that improves #prognostication in #HepatocellularCarcinoma, identifies high risk patients, and guides the development of novel #Immunotherapy strategies. #medsky

To read: doi.org/10.1007/s115...

Estudio liderado por el Dr. @alvarolladser.bsky.social muestra que una respuesta antitumoral duradera en terapia adoptiva con células T también depende de la inmunidad del huésped.
nature.com/articles/s41...

#Immunotherapy #NatureCommunications #USS #CentrosAnid

Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade Nature Medicine - Transcriptomic and clinical data analyses from multiple cohorts of patients with cancer receiving immunotherapy find that PD-1 blockade potentiates tumor-specific IgG1 plasma cell...

New research in @natmed.nature.com reveals IgG1 producing #Bcells are key to cancer #immunotherapy success. Data from 2k+ patients show these cells coordinate with T-cells to drive anti-tumor immunity. A shift toward humoral-cellular strategies could transform outcomes.

rdcu.be/e90xd

Read SITC’s call to action for development of an ICI irAE RWD registry and best practices for post-ICI survivorship care. View article published in the Journal for ImmunoTherapy of Cancer: https://ow.ly/2GxG50Ywqka

#immunotherapy #survivorship

New concepts for #glioblastoma vaccine #immunotherapy

www.sciencedirect.com/science/arti... #OpenAccess #cancer

Relevance of the IMDC Risk Model in a Real World Setting: A Single Institution Experience

by Kyaw Kyaw Tun, Loaie Elhelw and Salil Vengalil

Med. Sci. Forum 2025, 39(1), 5; www.mdpi.com/2673-9992/39...

renal #cancer; cytoreductive #nephrectomy; #immunotherapy

STING pathway nano-strategies in cancer
www.scienceopen.com/hosted-docum...
#STINGPathway #Nanotherapy #Immunotherapy #CancerTargets #DrugDelivery

uPAR shows up on the most dangerous cancer cells AND the support cells that protect tumors. Targeting both at once could be the breakthrough solid tumor patients have been waiting for. #TCSC #CancerScience #Immunotherapy #CancerBreakthrough

26-year-old now 'cancer-free' thanks to new colorectal cancer treatment A 26-year-old is now "cancer-free" after receiving a new treatment for colorectal cancer.

A 26-year-old beat Stage 3 rectal cancer in just 4 months using dual immunotherapy; no chemo, no surgery. This is precision medicine doing the impossible. Read her incredible story. abcnews.go.com/GMA/Wellness... #TCSC #CancerFree #ColorectalCancer #Immunotherapy

Forget Antibiotics: These Killer Cells Wipe Out Deadly Superbugs in a Day The genetically engineered cells can be rewired to tackle a range of bacteria in the battle against antibiotic resistance.

Forget Antibiotics: These Killer Cells Wipe Out Deadly Superbugs in a Day #Science #HealthandMedicine #InfectiousDiseases #Superbugs #Immunotherapy

singularityhub.com/2026/03/30/forget-antibi...

Exploring immunotherapy for colon cancer?

Mexico offers advanced options like checkpoint inhibitors & personalized care at affordable costs.

www.placidway.com/answer-detail/571370/Wha...

#ColonCancer #Immunotherapy

Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Harnessing lipid-driven immunometabolic pathways in omental metastases to enhance immunotherapy in patients with ovarian cancer

The pieces go very well together and show the immunomodulatory capacity of adipose tissue for #immunotherapy (see
doi.org/10.1038/s413...) & also linking up with the brilliant work by @leilaakkari.bsky.social on #macrophages :
doi.org/10.1016/j.ce...

#science #immunology #cancer