Amyloid plaques, shown here in pink via a transmission electron micrograph of an Alzheimer's patient's brain. Image credit: Science Source/THOMAS DEERINCK, NCMIR

Reprogrammed #astrocytes clear #Alzheimers #plaques in mice. In PNAS Journal Club: https://ow.ly/MgWU50YCrrr

#AlzheimersDisease #AmyloidPlaque #immunotherapy #AdenoAssociatedVirus

AAV-BI30, an endotheliotropic #AdenoAssociatedVirus for transducing vascular tree in #CentralNervousSystem Brain/Retina/Spinal Cord

👉>AAV-BR1 esp. in artery/vein

👉Also transduce #EndothelialCell in #Aorta/Liver/Lung/Kidney

@natcardiovascres.nature.com 2022
pmc.ncbi.nlm.nih.gov/articles/PMC...