Astrocytes in mouse amygdala encode emotional state The glial cells’ activity reliably tracks with freezing, hesitancy and other behaviors reminiscent of anxiety.

New findings suggest that #astrocytes cells, which are altered in people with some neuropsychiatric conditions including autism, contribute to #MentalHealth difficulties documented in such groups. www.thetransmitter.org/spectrum/astrocytes-in-m...

A stab at the brain: #Astrocytes (GFAP – cyan) and #microglia (Iba1 – magenta) took care of the damage and isolated the wound from the surrounding tissue. Normal distribution of neuronal NeuN (yellow) indicates the efficiency of the #glia based damage control. #FluorescenceFriday

Join us for a satellite symposium at #FENS2026 in Barcelona.
– Emerging roles of glial cells in brain function & disease

📅 July 5, 2026 |
🎟️ Early bird registration: 50€ (until Apr. 30)

🔗 networkglia.eu/activities/
#Neuroscience #GliaResearch #Astrocytes #FENS2026

Researchers Identify Astrocyte Pathway That Regulates Appetite and Fullness A recent study from the University of Maryland and the University of Concepción reveals that the brain relies on more than traditional neurons to decide when you feel full. The research, published in the Proceedings of the National Academy of Sciences, shows that astrocytes—widely thought to be support cells—play a critical role in controlling appetite. After eating, glucose levels rise, prompting tanycytes, specialized cells in the hypothalamus, to release lactate. This lactate binds to HCAR1 receptors on astrocytes, which then activate and release glutamate, signaling neurons that suppress hunger. Interestingly, this chain reaction connects multiple types of brain cells and spreads through the hypothalamus, demonstrating a complex communication network that regulates food intake. The team observed that lactate might interact simultaneously with two neuron populations: those promoting hunger and those inducing fullness. These findings could pave the way for new therapies for obesity and eating disorders by targeting astrocytes or the HCAR1 receptor specifically. The discovery represents nearly a decade of collaborative work between neuroscientists Ricardo Araneda and María de los Ángeles García-Robles, and offers promising insights into brain function and metabolic health.

Researchers Identify Astrocyte Pathway That Regulates Appetite and Fullness

🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️

#appetite #astrocytes #obesity

View full AI summary:

Astrocytes Play a Key Role in Forming and Regulating Fear Memories Recent research from the University of Arizona has revealed that astrocytes, brain cells previously considered mere support elements, are crucial in shaping fear memories. In a multi-institutional study led by Lindsay Halladay, Andrew Holmes, and Olena Bukalo, researchers discovered that astrocytes in the amygdala actively participate in forming, recalling, and weakening fear responses by interacting directly with neurons. Using fluorescent sensors in a mouse model, they observed that astrocyte activity increases during both the learning and recall of fear memories and declines as fear diminishes. Altering astrocyte signaling could either intensify or reduce fear responses, demonstrating that these cells actively shape how fear is stored and expressed. The study also found that changes in astrocyte activity influence neural circuits beyond the amygdala, including the prefrontal cortex, affecting decision-making in fearful situations. This breakthrough challenges the long-standing neuron-centered view of fear and opens up potential new treatments for anxiety-related disorders, including PTSD, by targeting astrocytes alongside neurons. Researchers aim to further explore the role of astrocytes throughout the brain’s fear circuitry to better understand inappropriate fear responses in anxiety disorders.

Astrocytes Play a Key Role in Forming and Regulating Fear Memories

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

#astrocytes #fear #ptsd

View full AI summary:

Amyloid plaques, shown here in pink via a transmission electron micrograph of an Alzheimer's patient's brain. Image credit: Science Source/THOMAS DEERINCK, NCMIR

Reprogrammed #astrocytes clear #Alzheimers #plaques in mice. In PNAS Journal Club: https://ow.ly/MgWU50YCrrr

#AlzheimersDisease #AmyloidPlaque #immunotherapy #AdenoAssociatedVirus

One week left to submit your proposal for #GLIA2027, Bologna, 7–10 July 2027.

Deadline: 8 April 2026, 12:00 p.m. CEST
Submit: https://www.glia-meeting.eu/2027/call-for-symposia/

#GlialCells #Astrocytes #Microglia #Oligodendrocytes #SchwannCells #NG2Cells #Neuroinflammation #Myelination

What a pleasure to listen to @soyonhonglab.bsky.social
talk about the role of microglia and astrocytes in neurodegenerative diseases at the 12th MCBiology Symposium, organized by the students of the MCBiology Doctoral Program @i3suporto.bsky.social 👏
#ERAChair #NCBio #microglia #astrocytes

Go go go submit a symposium proposal for #NeuroFrance2027!

And let’s make sure glial cells get the spotlight they deserve.
#Astrocytes, #microglia, #oligodendrocytes

Submit your proposal before 24 April 2026 👇

#glia #neuroscience #Bordeaux

Wild, wild news: my dream postdoc project on astrocyte computation in Danionella just got HFSP funding. Joining Volker Bormuth’s group at the Sorbonne soon and can’t wait to do some serious microscopy and coding. Stay tuned! #HFSP #danionella #astrocytes #HFSPAwardees

Original post on mastodon.social

Maladie #Alzheimer :
-> rôle des cellules #astrocytes qui participent à l'impression des souvenirs à long terme dans le #cerveau + peuvent être directement déclenchés par des expériences émotionnelles intenses répétées.

https://mastodon.social/@cobrate/114132196272432613

enjeux politiques de […]

1 month left to submit your #Glia2027 symposium proposal!

Deadline: 8 April 2026, 12:00 p.m. CEST
Submit here: http://www.glia-meeting.eu

Join us in Bologna, Italy (7–10 Jul 2027) and shape the future of glial research!

#GlialCells #Astrocytes #Oligodendrocytes #Microglia #SchwannCells

Once Thought To Support Neurons, Astrocytes Turn Out To Be in Charge | Quanta Magazine New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial la...

New experiments reveal how #astrocytes tune neuronal activity to modulate our mental and emotional states. www.quantamagazine.org/once-thought-to-support-...

Once Thought To Support Neurons, Astrocytes Turn Out To Be in Charge | Quanta Magazine New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial la...

New experiments reveal how #astrocytes tune neuronal activity to modulate our mental and emotional states. www.quantamagazine.org/once-thought-to-support-...

#AIGS26 | Day 1 (Sept 16) 🧠

Session 2: "New Insights on Glial Cells in Neurodegeneration: A Focus on Metabolism".

Speakers:
🔬 Alberto Pascual @ibis-investigacion.bsky.social #microglia #metabolism
🔬 Maite Solas @unav.edu #astrocytes #alzheimers
🔬 Vanja @tepavcevicvanja.bsky.social #myelin #MS

This review by Isabel N. Christie from @fohsheffield.bsky.social summarises the evidence that #astrocytes are essential for homeostasis of the #respiratory gases in the brain, with a particular focus on oxygen homeostasis 🧠 ⚖️

🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Astrocytes, the fibrous bodies shown here, in a light micrograph of brain tissue. Image credit: Science Source/JOSE CALVO

Long thought to play a supporting role in the #brain, #astrocytes appear to coordinate #fear memories alongside neurons. In PNAS Journal Club: https://ow.ly/eW2a50YphmZ

#memory #amygdala #PTSD #anxiety #cognition

Achucarro International Glia School is back! #AIGS26

Registration period is already open, and the final programme accessible.

Looking forward to this edition in #Plentzia

www.achucarro.org/gl...

#astrocytes #microglia #oligodendrocytes #glialcells

Super‑resolution images of Epm2b−/− astrocytes matured in culture and of hippocampal astrocytes from 16‑month‑old Epm2b−/− mice. Both sets of images show GFAP‑positive astrocytes (red), glycogen‑positive PGBs (green), and DAPI‑stained nuclei (blue), with magnified insets highlighting the granular PGB structures.

Mireia Moreno-Estellés, Pascual Sanz & co improved their astrocytic model of #LaforaDisease by maturing #astrocytes, showing that they accumulate larger and granular PGBs (insoluble glycogen form), recapitulating key characteristics of the disease.
Read doi.org/10.1242/dmm....
@ibv-csic.bsky.social

Italian scientists have established a significant connection between the #LRRK2 G2019S mutation, often associated with late-onset familial Parkinson's disease, and higher levels of clusterin in #astrocytes. 🔎

Learn more about the LRRK2-clusterin relationship on the blog 📍 https://bit.ly/4aH91XZ

Vanessa Chiappini and co-authors present this scoping review into ultrastructure of #astrocytes using volume electron #microscopy 📜 🔬

🔗 Read the paper: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Astrocytes Discovered as Architects of Fear Memory - Neuroscience News Astrocytes, long thought to be support cells, are actually critical for encoding, recalling, and extinguishing fear memories in the amygdala.

#Astrocytes Discovered as Architects of #Fear Memory
#Neuroscience

Astrocytes, not just neurons, found to drive fear memory signals in the amygdala Picture a star-shaped cell in the brain, stretching its spindly arms out to cradle the neurons around it. That's an astrocyte, and for a long time, scientists thought its job was caretaking the brain,...

#Astrocytes, not just #neurons, found to drive fear #memory signals in the #amygdala
#Neuroscience

Scientists Reveal Secret Repair System in the Spinal Cord Scientists uncover hidden brain cells that repair spinal cord injuries, offering new hope for treating paralysis, stroke and multiple sclerosis.

Scientists discover hidden brain cells that repair spinal cord injuries, offering breakthrough hope for paralysis, stroke, and multiple sclerosis patients.
#SpinalCordInjury #Neuroscience #LesionRemoteAstrocytes #Astrocytes #BrainScience

Brain cells birth zombielike transport vesicles Shed from the surfaces of astrocytes, “zombosomes” flit between cells, carrying proteins linked to disease

#Brain #cells birth #zombielike transport #vesicles
#ExtracellularVesicles #EVs #SelfDrive #Biology #Comms #SatNav #BodyNav #ParkinsonsDisease #Zombosomes #Science #Nature #OrganComms #Astrocytes
www.science.org/content/arti...

Enhancing the Astrocytic Clearance of Amyloid Beta Astrocytic Sox9 promotes amyloid beta clearance and preserves cognition, revealing new astrocyte-driven therapeutic strategies for Alzheimer’s disease.

💫 Enhancing Sox9 in #astrocytes upregulates the MEGF10-mediated clearance of #AmyloidBeta plaques, safeguarding cognitive function in #neurodegenerative disease models.

Review the key findings from this study on the StressMarq blog ⭐ https://bit.ly/4qZ2Eq7

Choi et al. (2026) shows that boosting Sox9 in astrocytes clears amyloid plaques in Alzheimer's mouse models and protects brain function. Is this a new therapeutic target? #Alzheimers #Neuroscience #Astrocytes #Research.

Check out the video!
youtu.be/SbhwxGqNv1Q

Once Thought To Support Neurons, Astrocytes Turn Out To Be in Charge | Quanta Magazine New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial la...

Once #Thought To Support #Neurons, #Astrocytes Turn Out To Be in #Charge | #QuantaMagazine. Jan 30 2026. #Brain #Biology #ChangeofState #Sleep #Life #Death #GiveUp #Signals #Boss #Command #Override #Change #PriorityShift #Nature #Science #Evolution www.quantamagazine.org/once-thought...

Astrocytes were the background NPCs of neuroscience - they might be calling the shots in our moods. www.quantamagazine.o... #astrocytes #neuroscience #mentalhealth #scifi #STEM

🎉 #GLIA2025 Spotlight: Ignacio S. Pizarro (Univ. of Santiago de Chile) shows intranasal Probenecid reduces astrocyte inflammation & myelin loss in a preclinical MS model—microglia unaffected! #GliaResearch @ignaciospizarro.bluesky.social #Neuroinflammation #Astrocytes #MyelinRepair