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The raccoon raiding your garbage bin might just be solving a puzzle—for the fun of it Ever woken up to find that a crafty raccoon has overturned your garbage bin and spread the discarded contents of your life across the street? Raccoons—sometimes referred to as "trash pandas"—are renow...

The #raccoon raiding your garbage bin might just be solving a puzzle—for the fun of it
First, they have a high number of #neurons packed into a relatively small brain. Their #neuronal_density is more similar to that of #primates than other #carnivores.
phys.org/news/2026-03...

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2P-NucTag: On-demand phototagging for molecular analysis of functionally identified cortical neurons 2P-NucTag enables on-demand and stable two-photon phototagging of single neurons following in vivo functional imaging in behaving mice. It reveals unexpected gene expression differences between hippoc...

2P-NucTag: On-demand #phototagging for #molecular analysis of functionally identified #cortical #neurons: Neuron www.cell.com/neuron/fullt...

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#Neurons rely on molecular motors to deliver proteins to precise locations. Jiang, Ichinose, Hirokawa et al. show that #kinesin-2 motors form heterogeneous assemblies with distinct cargo preferences: A KIF3B-enriched assembly preferentially associates with TRIM46 rupress.org/jcb/article/...

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#Neurons rely on molecular motors to deliver proteins to precise locations. In @jcb.org, Jiang, Ichinose, Hirokawa et al. show that #kinesin-2 motors form heterogeneous assemblies w/ distinct cargo preferences: A KIF3B-enriched assembly preferentially associates w/ TRIM46 rupress.org/jcb/article/...

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#Neurons on chip play game. Not very well yet - learning.

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Quantum behaviour in brain neurons looks theoretically possible – Physics World A study probing quantum phenomena in brain neurons could provide fresh insight into how our brains function

#Quantum #behaviour in #brain #neurons looks #theoretically #possible. 17 Mar 2025 #Penrose #Hameroff #Ghose #neuroscience #experiments #consciousness #entanglement #physics #biology #Pinotsis #FitzHugh #Nagumo physicsworld.com/a/quantum-be...

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Intactis Bio Corp's Lab-Grown Neurons Achieve Milestone in Biohybrid Computing with Investment Boost Intactis Bio Corp has made headlines by using lab-grown neurons to perform complex math and communicate, backed by a $250K investment.

Intactis Bio Corp's Lab-Grown Neurons Achieve Milestone in Biohybrid Computing with Investment Boost #USA #Salt_Lake_City #Neurons #Intactis_Bio #Biohybrid_Computing

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🛣️ Cellular Highways

A field of LUHMES-derived #neurons stained for actin (gold) & microtubules (cyan)

🔬Scientific #artwork by Joe McKellar from @cnrs.fr, @umontpellier.bsky.social

Published a neurobiology paper in 2025/2026 citing ibidi?

Submit it here : zurl.co/fbbIO

#bioart

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#MeetTheSpeaker - Protein Synthesis Beyond the Cell Body with Erin Schuman
#MeetTheSpeaker - Protein Synthesis Beyond the Cell Body with Erin Schuman YouTube video by Human Technopole

🧠 How does the brain make #proteins exactly where they’re needed?

🎙️ @erin-schuman.bsky.social, Director at @mpibrain.bsky.social, shared how #neurons produce proteins locally at synapses, shaping plasticity and memory.

youtu.be/GFj__978bdg

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30 NEURONS, STRUCTURE AND FUNCTION OF THE NERVOUS MESSENGERS #50LAM_ANATOMY_ENG
30 NEURONS, STRUCTURE AND FUNCTION OF THE NERVOUS MESSENGERS #50LAM_ANATOMY_ENG YouTube video by 50 LIKE A MACHINE

30 NEURONS, STRUCTURE AND FUNCTION OF THE NERVOUS MESSENGERS #50LAM_ANATOMY_ENG
youtube.com/shorts/LjHpi...
#neurons #nervoussystem #neuronstructure #axon #dendrites #myelinsheath #synapse #neurotransmitters #sensoryneurons #motorneurons

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27 OVERVIEW OF THE NERVOUS SYSTEM, COMMAND CENTER OF THE BODY #50LAM_ANATOMY_ENG
27 OVERVIEW OF THE NERVOUS SYSTEM, COMMAND CENTER OF THE BODY #50LAM_ANATOMY_ENG YouTube video by 50 LIKE A MACHINE

27 OVERVIEW OF THE NERVOUS SYSTEM, COMMAND CENTER OF THE BODY #50LAM_ANATOMY_ENG
youtube.com/shorts/ERkbn...
#nervoussystem #brainandspinalcord #cns #pns #autonomicnervoussystem #neurons #neurotransmitters #nervoussystemanatomy #neuroscience #humananatomy

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Check out the latest #PhysiologyShort to hear from Dr. Emi Narai & Prof. Satoshi Koba as they take us behind their published paper, titled 'Orexinergic #neurons contribute to autonomic #cardiovascular regulation for locomotor exercise' 🧠 🫀

📹️ www.youtube.com/watch?v=71bZ...

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The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

Does #wakefulness induced by pharmacological or non-pharma routes involve different #neurons? This study of whole-brain activation patterns in mouse shows that solriamfetol, modafinil & non-pharma #arousal recruit overlapping but distinct subcortical populations @plosbiology.org 🧪 plos.io/4soFNVK

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The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

Does #wakefulness induced by pharmacological or non-pharma routes involve different #neurons? This study of whole-brain activation patterns in mouse shows that solriamfetol, modafinil & non-pharma #arousal recruit overlapping but distinct subcortical populations @plosbiology.org 🧪 plos.io/4soFNVK

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The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

The neuronal network of the wakefulness system activated by solriamfetol (Sol), modafinil (Mod) and non-pharmacological wakefulness (NW). Drawing showing many interconnected structures implicated in wakefulness, after Sol, and Mod injections and NW. The pink structures are significatively more activated by Sol than Mod and NW. Sol strongly activates a subset of structures less activated in non-pharmacological wakefulness (NW) and only weekly activated by Mod. The blue structures are activated by Sol, Mod and NW. The white ones are known to be implicated in the wake system, for the DRN, LC and TMN, their role is minor based on our results. Different neurotransmitters are involved in this system inhibiting or exciting wake structures, Like gamma-aminobutyric (GABA), glutamate (Glu), norepinephrine (NA), Histamine (Hist), acetylcholine (Ach), Orexin (Orx), dopamine (DA), serotonin (5HT), oxytocin (OT), vasopressin (VP), corticotropin-releasing hormone (CRH), and calcitonin gene-related peptide (CRGP). ACB: accumbens nucleus, BNSTOval: bed nucleus of the stria terminalis, anterior division, oval nucleus, CEAl: central amygdalar nucleus, lateral part, DRN: dorsal raphe nucleus, LC: locus coeruleus, LDT: laterodorsal tegmental nucleus, LH: lateral hypothalamus, LPBExt: lateral parabrachial nucleus, external part, LRN: lateral reticular nucleus, NTSc: nucleus of the solitary tract, caudal part, PSTN: parasubthalamic nucleus, PVN: paraventricular nucleus of the hypothalamus, PVT: paraventricular nucleus of the thalamus, SO: supraoptic nucleus, TMN: tuberomammillary nucleus, VLPO: ventrolateral preoptic area, VTA: ventral tegmental area. Created in BioRender. Team, S. (2026)

Does #wakefulness induced by pharmacological or non-pharma routes involve different #neurons? This study of whole-brain activation patterns in mouse shows that solriamfetol, modafinil & non-pharma #arousal recruit overlapping but distinct subcortical populations @plosbiology.org 🧪 plos.io/4soFNVK

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Stress can cause eczema to flare-up – now we know why Scientists have identified the neurons that worsen the condition during stress.

Researchers have identified the link between stress and #eczema. They identified a network of #neurons that respond to stress by activating #immune cells in the skin, causing eczema symptoms. #dermatology
www.nature.com/articles/d41...

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In this comparative study, Guanxiao Qi and colleagues from @fz-juelich.de investigate #transport-related effects on intrinsic and synaptic properties of human cortical #neurons 🧠 🧫

📜 Read the #Research featuring on the latest cover: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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Most animals except for sponges share fundamentally similar #neurons and #hormones due to their common evolutionary history. Jellyfish (and their microbiome) produce the same #dopamine and #serotonin as humans do.
theconversation.com/chemical-imb...

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Kicking off #BrainAwarenessWeek with a #MicroscopyMonday showing an adult fruit fly #brain imaged on a confocal microscope, sweet-sensing #neurons are seen in yellow, while magenta shows the neuronal connections. (Si Lab) 🧠 #BrainWeek

@danafoundation.bsky.social @brainfacts.org @sfn.org

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Awakari App

Learning to Build a Single Neuron Below is a cleaned, grammatically correct version of your paragraph while keeping your tone and intent the same. Continue reading on Medium »

#neurons #how-ai-works #llm-learning #machine-learning #ai-learning

Origin | Interest | Match

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Takaki Yahiro, Yoshiko Nakamura & Kazuhiro Nakamura from @en.nagoya-u.ac.jp
present a potential mechanism of chills, in that the pyrogenic mediator #prostaglandin E2 elicits warmth seeking via EP3 receptor-expressing parabrachial #neurons 🧠 🌡️

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

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1/19 During the non-mated phase when females were actively hunting and eating, they produced #high #levels of #neuropeptides, or small protein molecules used by #neurons to #communicate with each other that have been linked to feeding behavior in many animals.

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#Cholesterol in cell membranes plays a key role in controlling how #pain-sensing #neurons respond. Handlin et al. show that distinct cholesterol pools—OMD-associated & freely accessible cholesterol—differently influence HCN #IonChannels, which regulate nerve excitability. rupress.org/jgp/article/...

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#Cholesterol in cell membranes plays a key role in controlling how #pain-sensing #neurons respond. Handlin et al. show that distinct cholesterol pools—OMD-associated & freely accessible cholesterol—differently influence HCN #IonChannels, which regulate nerve excitability. rupress.org/jgp/article/...

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AC$\oplus$DC search: behind the winning solution to the FlyWire graph-matching challenge

Daniel Lee, Arie Matsliah, Lawrence K. Saul

Action editor: Giannis Nikolentzos

https://openreview.net/forum?id=8MjCOMyaDf

#neurons #graphs #optimizations

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Does This Fly Prove We're In a Simulation?
Does This Fly Prove We're In a Simulation? YouTube video by Matthew Berman

" #BrainEmulation: The fly's behavior is 91% accurate to its biological counterpart based on the mapped connections, excitatory/inhibitory #neurons, and firing rules" #AI #simulation

youtu.be/N2ccho6ug1w?...

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An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons This work introduces an open-source all-optical platform for functional phenotyping of human stem cell-derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and...

Publication alert! We built an #opensource platform for functional phenotyping of hiPSC-derived #neurons, combining calcium #imaging, #optogenetic stimulation, #automated acquisition and analysis into an accessible workflow. @fedegasparoli.bsky.social @sahinm.bsky.social @sciwhye23.bsky.social

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Huge congrats to Brian Joseph, postdoc in the lab, on his
NIH #K99 award—now official after a long wait! 🎉

Brian will study #RNA regulatory mechanisms to generate more mature #neurons in culture , creating improved models for adult-onset neurodegenerative diseases and accelerating drug discovery.

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LATEST COVER IMAGE 📸

The latest issue of JP features imagery from Guanxiao Qi and colleagues' study into transport-related effects on intrinsic and synaptic properties of human #cortical #neurons 🧠

📖 Read the issue: physoc.onlinelibrary.wiley.com/toc/14697793...

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Newly identified brain circuit and cells link prior experiences to appetite Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identifi...

⚡ Newly identified brain circuit and cells link prior experiences to appetite

medicalxpress.com/news/2026-02...

#brain #food #appetite #neurons #hunger #biology #behavior #memory

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