This review examines the #Molecular hierarchy and roles of #SKP2 in #CellularHomeostasis, and maps current #therapeutic strategies, aiming to build a #Translational atlas that supports future SKP2-directed interventions for #Cancer and other disorders.
#OpenAccess: amm-journal.org/index.php/20...

World Health Day 2026: Together for health. AMM supports this mission by publishing high-impact research on drug delivery, molecular pharmacology, and traditional medicine to advance global health outcomes. #ScienceMatters
Go to: amm-journal.org

Network pharmacology-guided discovery of avicularin from Euphorbia humifusa Willd. targeting IL-17 signaling in psoriasis This research demonstrates that Euphorbia humifusa Willd. extract and avicularin inhibit inflammation and abnormal keratinocyte proliferation in psoriasis.

This research demonstrates that #Euphorbia humifusa Willd. extract and avicularin inhibit inflammation and abnormal #keratinocyte proliferation in psoriasis.

#OpenAccess: amm-journal.org/index.php/20...

DT-13 ameliorates LPS-induced acute lung injury via targeting NMMHC IIA to modulate the FOXO1/KLF2/SPHK1 pathway This study identifies NMMHC IIA as a key mediator of LPS-induced injury via regulation of the FOXO1/KLF2/SPHK1 pathway and demonstrates that DT-13 preserves endothelial barrier function

This study identifies #NMMHC IIA as a key mediator of LPS-induced injury via regulation of the #FOXO1/KLF2/SPHK1 pathway and demonstrates that #DT-13 preserves endothelial barrier function.

#OpenAccess: amm-journal.org/index.php/20...

Boosting pancreatic cancer chemotherapy via nerve–cancer crosstalk
www.scienceopen.com/hosted-docum...
#PancreaticCancer #Chemotherapy #TumorMicroenvironment #Neurobiology #CancerTherapeutics

Ferroptosis by nanomaterials targeting cancer stem cells
www.scienceopen.com/hosted-docum...
#Ferroptosis #Nanomaterials #CancerStemCells #TargetedTherapy #CancerResearch

Estrogen receptor-targeted agents in breast cancer
www.scienceopen.com/hosted-docum...
#BreastCancer #EstrogenReceptor #TargetedTherapy #HormoneTherapy #Oncology

Antineoplastic effects of icaritin
www.scienceopen.com/hosted-docum...
#Icaritin #Antineoplastic #NaturalCompounds #CancerTherapeutics #DrugDevelopment

Cuproptosis-related MTF1 in renal cancer
www.scienceopen.com/hosted-docum...
#Cuproptosis #MTF1 #RenalCancer #CellDeath #CancerTargets

STING pathway nano-strategies in cancer
www.scienceopen.com/hosted-docum...
#STINGPathway #Nanotherapy #Immunotherapy #CancerTargets #DrugDelivery

Aging and cancer hallmarks as therapeutic targets
www.scienceopen.com/hosted-docum...
#Aging #CancerHallmarks #TherapeuticTargets #CancerBiology #PrecisionMedicine

Submit your research to Acta Materia Medica
mc04.manuscriptcentral.com/ammed
#CallForPapers #CancerResearch #Oncology #PublishYourResearch

Exploring advances in Cancer Therapeutics, Targets & Resistance from Acta Materia Medica
Discover cutting-edge research: amm-journal.org
#CancerResearch #CancerTherapeutics #DrugResistance #Oncology

PROTACs improve selectivity for targeted proteins
www.scienceopen.com/hosted-docum...
#PROTAC #ProteinSelectivity #TargetedDegradation #DrugDesign #ChemicalBiology

Application of PROTACs in target identification and validation
www.scienceopen.com/hosted-docum...
#PROTAC #TargetIdentification #TargetValidation #DrugDiscovery #ChemicalBiology

PROTAC technology for prostate cancer treatment
www.scienceopen.com/hosted-docum...
#PROTAC #ProstateCancer #TargetedTherapy #ProteinDegradation #Oncology

PROTACs targeting epigenetic proteins
www.scienceopen.com/hosted-docum...
#PROTAC #Epigenetics #EpigeneticTargets #ProteinDegradation #CancerResearch

Multi-specific antiviral PROTAC modality
www.scienceopen.com/hosted-docum...
#PROTAC #Antiviral #TargetedDegradation #DrugDiscovery #ChemicalBiology

MDM2-BCL-XL PROTACs
www.scienceopen.com/hosted-docum...
#PROTAC #MDM2 #BCLXL #Apoptosis #ProteinDegradation

PROTAC degraders recruiting MDM2
www.scienceopen.com/hosted-docum...
#PROTAC #MDM2 #E3Ligase #TargetedDegradation #DrugDesign

Submit your research to Acta Materia Medica
mc04.manuscriptcentral.com/ammed
#DrugDiscovery #ChemicalBiology

Advancing PROTACs & Targeted Protein Degradation from Acta Materia Medica
Explore the latest research: amm-journal.org
#PROTAC #TargetedProteinDegradation #DrugDiscovery #ChemicalBiology

AI applied to Traditional Chinese Medicine—data-driven methods unlocking new therapeutic insights
www.scienceopen.com/hosted-docum...
#AI #TCM #DigitalHealth #ComputationalMedicine

New thinking in drug R&D tackling intractable scientific challenges—reshaping therapeutic innovation
www.scienceopen.com/hosted-docum...
#DrugDiscovery #R&D #PharmaInnovation #TranslationalScience

Response regression models advancing host-targeted antivirals—innovating beyond pathogen-focused approaches
www.scienceopen.com/hosted-docum...
#Antivirals #HostDirectedTherapy #ComputationalBiology #InfectiousDisease

Machine learning-powered aptamer modification—enhancing precision and therapeutic performance
www.scienceopen.com/hosted-docum...
#MachineLearning #Aptamers #Biotherapeutics #MolecularEngineering

AF2-mutation strategies expanding protein structure prediction—deepening AI’s role in therapeutic discovery
www.scienceopen.com/hosted-docum...
#AlphaFold #ProteinStructure #AIinBiology #StructuralBiology

Computational strategies accelerating PROTAC discovery—driving next-generation targeted therapeutics
www.scienceopen.com/hosted-docum...
#PROTAC #DrugDiscovery #ComputationalChemistry #TargetedDegradation

Submit your work on AI-driven drug discovery & therapeutic innovation to AMM
mc04.manuscriptcentral.com/ammed
#CallForPapers #Biotech #Pharma #AIResearch

AI-driven approaches are transforming drug discovery & therapeutic innovation—explore the latest research from @AMM_Journal
amm-journal.org
#AI #DrugDiscovery #TherapeuticInnovation #Biotech