Network pharmacology-guided discovery of avicularin from Euphorbia humifusa Willd. targeting IL-17 signaling in psoriasis This research demonstrates that Euphorbia humifusa Willd. extract and avicularin inhibit inflammation and abnormal keratinocyte proliferation in psoriasis.

This research demonstrates that #Euphorbia humifusa Willd. extract and avicularin inhibit inflammation and abnormal #keratinocyte proliferation in psoriasis.

#OpenAccess: amm-journal.org/index.php/20...

Autocrine IL-8 Contributes to Propionibacterium Acnes-induced Proliferation and Differentiation of HaCaT Cells via AKT/FOXO1/ Autophagy

This study demonstrates that P. acnes-induced #IL8 & the downstream AKT/#FOXO1 pathway regulate #Keratinocyte #Proliferation & #Differentiation in #AcneVulgaris, pointing to potential therapeutic targets for clinical application. #medsky
To read: doi.org/10.1007/s115...

Awesome story about #lamellar bodies, unique #keratinocyte #organelles secreted as the “mortar” of the #epidermis that prevents our #skin from drying out. We were ecstatic to play a small part. Especially cool since the organelle was discovered decades ago by Dr Odland at @uwdermatology.bsky.social.

Redirecting

New collab out with Jennifer Zhang & Amy Petty of @dukemedschool.bsky.social #Dermatology Department! #scRNAseq performed by #DukeMGC

'Insights into #Keratinocyte and Immunologic Landscape in #Cutaneous #Graft-Versus-Host Disease through #SingleCellTranscriptomics' 🧬💻

doi.org/10.1016/j.xj...

Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-versus-host Disease through Single Cell Transcriptomic Cutaneous manifestations are the most common presenting sign of chronic graft-versus-host disease (cGVHD) and the extent of cutaneous involvement is a…

Amy Petty, postdoc of Jennifer Zhang's lab, 2025 publication inspired the talk - 'Insights into complex #keratinocyte landscape in acute and chronic #cutaneous #GVHD through single cell RNA sequencing’: sciencedirect.com/science/arti...

IOB's latest as part of the special grouping:
#Regeneration and the #NervousSystem-

#Sensory nerve-secreted factors regulate basal
#keratinocyte function in vitro
Srivastava, Noble, Payne
doi.org/10.1093/iob/...

#proteomic #science #healing #inflammation #biology #organisms

A study published in Burns & Trauma has shed light on how inhibiting CYP24A1, an enzyme involved in vitamin D metabolism, affects keloid keratinocytes.
#Keloid #Keratinocyte
Details: doi.org/10.1093/burnst/tkae063

A study published in Burns & Trauma has shed light on how inhibiting CYP24A1, an enzyme involved in vitamin D metabolism, affects keloid keratinocytes.
#Keloid #Keratinocyte
Details: doi.org/10.1093/burnst/tkae063